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Cofactors

Cofactors, coenzymes and prosthetic groups

QuestionAnswer
What is Zinc (Zn2+) needed for? Needed to make Carbonic Anhydrase, necessary for insulin to work.
What is Iron (Fe3+) needed for? Haem group for Haemoglobin, haem group for Catalase (also prosthetic group)
What is Cobalamin needed for? Coenzyme for Vitamin B12
What is Tetrahydrofolate needed for? Coenzyme for Folic acid
What is NAD/NADP needed for? Coenzyme for Vitamin B3
What is a coenzyme? They are small, organic, non-protein molecules that bind temporarily to the active site of an enzyme, they are chemically changed during the reaction.
What is a prosthetic group? A cofactor that is permenantly bound to the enzyme by covalent bonds.
What are co-substrates? Cofactors that form together with the substrate. They are complimentary to the active site.
Created by: katieappleton