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Cofactors
Cofactors, coenzymes and prosthetic groups
Question | Answer |
---|---|
What is Zinc (Zn2+) needed for? | Needed to make Carbonic Anhydrase, necessary for insulin to work. |
What is Iron (Fe3+) needed for? | Haem group for Haemoglobin, haem group for Catalase (also prosthetic group) |
What is Cobalamin needed for? | Coenzyme for Vitamin B12 |
What is Tetrahydrofolate needed for? | Coenzyme for Folic acid |
What is NAD/NADP needed for? | Coenzyme for Vitamin B3 |
What is a coenzyme? | They are small, organic, non-protein molecules that bind temporarily to the active site of an enzyme, they are chemically changed during the reaction. |
What is a prosthetic group? | A cofactor that is permenantly bound to the enzyme by covalent bonds. |
What are co-substrates? | Cofactors that form together with the substrate. They are complimentary to the active site. |