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Biology Chapter 3

Study Activities for Antimicrobial MCB2010

QuestionAnswer
The ______ the therapeutic index the better the drug. higher
This chemotherapeutic agent acts to inhibit protein synthesis by binding to the 30S ribosomal subunit and inhibiting amino acyl t-RNA binding. Tetracycline
Name the 2 chemotherapeutic agents which act upon transpeptidization to inhibit cell wall synthesis. Penicillin & Cephalosporin
These 2 chemotherapeutic agents disrupt the plasma membrane by acting on ergosterol in fungal cells. Nystatin & Amphotericin B
The region surrounding a paper disk impregnated with the antibiotic, where the bacteria are not growing. Zone of Inhibition
This chemotherapeutic agent acts to inhibit nucleic acid synthesis by binding to RNA Polymerase and blocking transcription. Rifamycin
What is the major component of penicillin that makes it active? Beta-lactam ring
What are the 2 anti-fungals that are systemic treatments? Amphotericin B & Flucytosine
_____ spectrum drugs are effective against a wide range of pathogens. Broad
Another name for the disk diffusion method to test antimicrobials using paper filter disks. Kirby Bauer Test
Name the 2 chemotherapeutic agents which inhibit linear peptidoglycan formation, which inhibits cell wall synthesis. Vancomycin & Bacitracin
The lowest concentration required to kill the microbe. Minimal Bactericial Concentration
The term for agents which slow or limit the growth of the pathogen. Bacteristatic
When a drug kills the infectious agent with low or no side effects to the host, it is said to be _____. Selectively Toxic
This anti-viral drug is a Thymine analog which is used to treat HIV patients. AZT
A superficial anti-fungal is _____. Miconazole
The term for agents which kill the pathogen. Bactericidal
_____ spectrum drugs are effective against a limited range of pathogens. Narrow
The lowest concentration required to limit the growth of the microbe. Minimal Inhibitory Concentration
This anti-viral drug works to prevent Influenza A infections. Amantadine
These chemotherapeutic agents work to block folic acid synthesis, thus inhibiting a key enzymatic process. Sulfonamides
Streptomycin, Spectinomycin, Chlormaphenicol, Clindimycin, Erythromycin, Gentamycin, Tetracycline 7 drugs to Inhibit Protein Synthesis
What is the main sterol component in fungal plasma membranes? Ergosterol
This chemotherapeutic agent acts to inhibit nucleic acid synthesis by inhibiting DNA Gyrase. Quinolones
This chemotherapeutic agent disrupts the plasma membrane by acting as a surfactant. Polymyxin
The _______ measures the toxic dose over the therapeutic dose. Therapeutic Index
This anti-viral drug is a Guanine analog which is used to treat genital herpes patients. Acyclovir
What is another name for penicillinase? Beta-lactamase
This chemotherapeutic agent acts to inhibit protein synthesis by inhibiting peptidyl transferase, by binding to the 50S ribosomal subunit. Chloramphenicol
Another name for 6-amino penicillanic acid? Penicillin
This chemotherapeutic agents acts to inhibit protein synthesis by binding to the 30S ribosomal subunit, causing mis-reading of the mRNA. Streptomycin
What is the main sterol component in animal cell plasma membranes? Cholesterol
Created by: mikec35-pbsc
 

 



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