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MUA M2B2 IDR Tcells

Tcell pathways

1. Th2 differentiated by GATA3 transcription factor
2. Treg differentiated by FoxP3 transcription factor
3. Th2 produces IL4, IL5, IL6, IL10, IL13, TGF-B
4. Th1 differentiated by T-Bet transcription factor
5. Th17 differentiated by RORyT transcription factor
6. Treg produces TGF-B, IL-35, IL-10
7. Th17 produces IL17, IL21, IL22
8. Th1produces IL2, IFNy, TNFa
9. Th0 is stimulated into Th17 by TGF-B, IL6
10. Th0 is stimulated into Th1 by IL12, IFNy
11. Th0 is stimulated into Treg by TGF-B, IL12
12. Th0 is stimulated into Th2 by IL4, IL2
13. Cell mediated immunity and inflammation is done by Th1
14. Antibody mediated immunity, allergies and parasites is done by Th2
15. Immune tolerance is done by Treg
16. Fungi , extracellular immunity, neutrophil enhancement is done by Th17
Created by: splashgreen