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GBCN Pharm Ch 19

Frandsen, G., & Pennington Abrams' clinical drug therapy: CH 19

TermDefinition
Concentration-dependent bactericidal effect elation of bactericidal ability of a drug to its concentration the greater the concentration of the drug, the faster and the more extensive the killing of the bacteria. The goal is to maximize concentration of the drug.
Extended-interval dosing dosing regimen that provides once-daily administration of an aminoglycoside with demonstrated decreased nephrotoxicity and ototoxicity while maintaining therapeutic efficacy also called pulse dosing
Ototoxicity adverse effects on the structures of the ear, especially the cochlea and auditory nerve
Postantibiotic effect persistent effect of an antimicrobial on bacterial growth after brief exposure of the organisms to a drug
Created by: shenderson36
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