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Equation Review

FA Important Equations

QuestionAnswer
Volume of distribution (Vd) (amount of drug in the body) =------------------------------------ (plasma drug concentration)
Half-life (t 1/2) (0.7 x Vd) = ---------------- ( CL)
Drug clearance (CL) ( rate of elimination of drug) = -------------------------------------- ( plasma drug concentration)
Drug clearance (CL) = (Vd x Ke) (Ke is the elimination constant)
Loading dose (LD) (Cp x Vd) = ---------------- F
Maintenance dose (D) (Cp x CLx t) = ------------------- F
Sensitivity TP = --------------- (TP + FN)
Specificity TN = ------------------ (TN + FP)
Positive Predictive Value (PPV) TP = -------------- (TP + FP)
Negative Predictive Value (NPV) TN = -------------- (FN + TN)
Odds ratio (for case control studies) (OR) a/c ad = ------- ==> --------------- b/c bc
Created by: rakomi
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