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Med Surg 2 Immune
Final Review
| Question | Answer |
|---|---|
| 5 Types of WBC | Neutrophil, Lymphocyte, monocyte, eosinophil, basophil |
| what is cell mediated response | cell to cell combat with bacteria, involves T cells |
| what is humoral response | involves B cells and complement system, associated with antibodies w/ viruses |
| two types of B cells | plasma cells, memory cells |
| job of plasma cell | produce antibodies |
| job of memory cell | memorize an antigen or foreign substances in the body- when activated they accumulate in the lymph tissue (swollen lympnodes) |
| 3 types of T cells | helper T, cytotoxic T, suppressor T |
| job of helper T cell (CD4) | fight infection, stimulates antibodies |
| job of suppressor T cell | turns off immune system response when antigen is eliminated |
| job of cytotoxic T cell (killer T) | combats directly with antigen, stims cytokines, promote T&B cell maturation |
| describe the complement system | proteins coat an antigen that makes it detectable by phagocytes, antigen goes through lysis |
| basophils are responsible for what response | allergic response- stores and releases histamine |
| eosinophls are responsible for what response | calming down an allergic response |
| two types of phagocytes | monocytes, neutrophils |
| name lymph tissues in the body | thymus, tonsils/adenoids, spleen, lymph nodes |
| function of thymus | mature T cells |
| function of spleen | filter bacteria and old, damaged RBC |
| function of lymph nodes | filter lymph |
| NK cells- natural killer | 2nd line of defense-virus and cancer cells, react fast but no memory of antigen |
| 5 types of antibodies | IgA, IgE, IgD, IgG, IgM |
| 2 cytokines | interleukins, interferons |
| interleukins do what | promote fever and inflammation- grow and activate NK cell |
| interferons do what | protect from viral invasion, slows viral growth, stim NK activity |
| ex. direct infection immunity | Natural Aquired Active |
| ex. immunization immunity | Artificially Acquired Active |
| ex. mother to newborn, breastmilk immunity | Naturally Acquired Passive |
| ex. ready-made antibodies, injected | Artificially Acquired Passive |
| what is sensitization | first exposure to an allergen |
| Types of Immediate Hypersenstivity | Anaphylactic, Cytotoxic, Immune Complex, Delayed |
| What happens in Anaphylactic sensitivity | minutes onset, vasodilation, angioedema, hypotension, WHEEZING |
| what happens in cytotoxic sensitivity (ABO incompatibility) | minutes to hours onset, FLANK PAIN, hematuria, fever, chills, impending doom |
| what happens in immune complex sensitivity | within 6 hours, inflammatory reactions... Lupus |
| what happens in delayed sensitivity | hours to days onset, no antibody production, unexplained fever, anemia- ex. TB skin test, organ rejection |
| what medication is administered during anaphylaxis | epi- mast cells |
| scratch test | skin scraped and multiple liquid antigen on skin- results in 20 min |
| patch test | one substance with occlusive dressing- results in 48 hour |
| main side effect of diphenhyrdamine | drowsiness, dry mouth |
| what is a contraindication of anithistamine | hx of LR d/o (COPD)- can make it difficult to expectorate |
| what is an autoimmune d/o | killer T and autoantibodies attack "self" cells |
| Lupus is a AI of what part of the body | connective tissue |
| Lupus symptoms | BUTTERFLY RASH, joint swelling, Raynaud's |
| Diagnostic test for Lupus | Antinuclear Antibody Titer (ANA)- should be - but 90% of lupus pt are + |
Created by:
torrieb3
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