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Immunity
study set
| Term | Definition |
|---|---|
| Inate immunity involves what..... | -Chemical -Processes -Receptor -Barriers cells |
| TLR | Toll -like receptor |
| PAMPs | pathogen associated molecular pattern |
| DAMPs | Damage associated molecular pattern |
| Defense mechanism | Keeps the microbe out of the body through external barriers |
| Non specific defense mechanism | INTERNAL defense that combat all invading microbes (inate) |
| Adaptive mechanism | Directly assaults an immune response against specific microbes |
| Inate immunity | non specific defense - LACK MEMORY (0 to 12 hrs response time) |
| Acute phase reactants | produced by tissue macrophages act on cell close to origin chemokine production |
| Chemokine | recruit WBC to site |
| what are the four chemokine families? | C, CC, CXC, CX3C |
| Granulocytes are..... | -Neutrophil -Eosinophil -Basophil -Mast cell |
| Neutrophil | Most abundant leukocyte -Phagocyte - releases substance in blood |
| Eosinophil | 2-4% leukocyte -kills parasites -phagocytic |
| Basophils | 0-1% leukocytes -release inflamatory response |
| Mast cells | < 1% leukocyte release histamine allergic response |
| Lympocytes are........ | adaptive immunity ------- NK cells |
| NK cells are considered to be what | Inate immunity |
| Arangulocytes | Monocyte macrophage dentritic cells NKC |
| Monocytes | in the blood -phagocytic macrophage when moves to tissues |
| macrophages | -tissue type -phagocytic -APC's antigen presenting cells |
| Dentritic cells | collect antigen from tissues - bring to lympocytes -APC's |
| NKC | natural killer cells |
| Ruber | Red |
| Calor | heat |
| Dolor | pain |
| tumor | swell |