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Pharm
| Drug | Indication | Side effect | Teaching | Brand name |
|---|---|---|---|---|
| Methylergovine | Causes uterine contraction to prevent hemorrhage | Seizures, htn, chest pain, toxemia, urinary retention, blurred vision, hand/foot tingling | Use gloves when administering, wait 12 hrs after last dose to breast feed, monitor bp and pulse | Methergine |
| Tamsulosin | Given for BPH | Angina, floppy iris syndrome, hypotension, dizziness, headache, rhinitis | Monitor urine, BP, liver function tests NO ST JOHNS WORT Do not crush, chew, open Give 1 hr before or 2 hrs after meal Rise slowly due to risk of hypotension | Flomax |
| Oxytocin | Increases uterine contraction Stop post partum hemorrhage | Seizures, coma, anxiety, sub-arachnoid hemorrhage, hypotension, tachycardia, uterine rupture, dysrhythmias | Monitor vital signs, fetal heart rate, and uterine tone | Pitocin |
| Oxybutynin | Treatment of overactive or neurogenic bladder | Dry mouth, drowsiness, confusion, agitation, blurred visio , diarrhea | Avoid prolonged hot weather | Ditropan |
| Regular insulin | Lowers blood glucose | Anaphylaxis, erythema, edema, hypoglycemia | Monitor potassium levels and glucose levels Onset 30 to 60 min Monitor weighr | Humulin R Novolin R |
| NPH insulin | Lowers blood glucose | Hypoglycemia, pruritis, erythema, swelling, anaphylaxis | Monitor I&O, weight, glucose Do not mix with other insulin Do not use if cloudy | Humalin N |
| Lactulose | Decreases ammonia levels in patients with liver disease | Belching, cramps, flatulence, diarrhea | Normal ammonia level 15-45 Assess abdomen and bowel function Monitor electrolytes Take with full glass of water | |
| Digoxin | Makes heart contract stronger and slower | Dizziness, confusion, depression, anxiety, n/v/d, rash, bradycardia, ARRHYTHMIAS | Monitor apical pulse for 1 full min Hold if pulse <60 Monitor serum electrolytes (K+, Mg, Ca), Renal and Hepatic functions Lasix and thiazides may cause toxicity (blurred vision, yellow/green visual disturbances, halo) ANTIDOTE=Digibind | Lanoxin |
| Ramipril | Decreases BP Reduce risk of MI, stroke | Dizziness, drowsiness, fatigue, headache, insomnia, vertigo, dyspnea, chest pain, pruritus, angioedema, myalgia | Monitor bp and weight Assess for fluid overload, chf, angiodema Labs- bun, creatinine, K+, cbc, ast, alt Avoid salt substitutes and high K+ food Report dry cough | Altace |
| Epoetin alfa | Treatment for anemia RBC deficiency (stimulates RBC production) | Htn, headache, cva, tia, mi, stroke, nausea, diarrhea, edema | Monitor BP, PTT, INR Do not shake May give prior to blood transfusion IV or SQ May decrease bleeding time Seizure precautions for rapid increase in hematocrit Supplement iron | Procrit Epogen |
| Vancomycin | Treats c diff, staph infections | tachycardia, red man syndrome (face flushing, hypotension, rash),anaphylaxis | Mix with No less than 250 ml of NaCl Adminsiter over 60 min Monitor BP and trough levels Assess 8th cranial nerve function | Vancocin |
| Dopamine | Given for shock and tachyarrhythmias Increases BP Renal dilation | Headache, anxiety, hypotension, tachycardia, n/v, palpitations, hyperglycemia, dyspnea, anaphylaxis, asthmatic episodes | Monitor VS, ECG, urinary output Assess for chest pain, numbness, tingling, or burning of extremities | Intropin |
| Indomethacin | Rheumatoid Arthritis Osteoarthritis Bursitis Tendonitis Gouty Arthritis | Abdominal pain, GI bleed, insomnia, headaches, dizziness, somnolence | Assess for GI bleeding Photosensitivity | |
| Mafenide Acetate | Antimicrobial for burns or bacterial infection | Blisters, tachypnea, n/v, diarrhea, headache, dark urine, weakness, abdominal pain,anaphylaxis | Monitor acid base, bun, creatinine, cbc | |
| Spironolactone | Potassium sparing diuretic Chf Ascites secondary to cirrhosis | Hyperkalemia, gynecomastia, muscle cramps, arrhythmia | Monitor I&O and daily wt Monitor K+ level, BP Avoid salt substitutes | Aldactone |
| Methotrexate | Rheumatoid Arthritis Breast cancer Leukemia Lymphoma | Anorexia, hepatotoxicity, n/v, stomatitis, anemia, leukopenia, nephropathy Do not touch with bare skin | Monitor vs, daily weight, liver and renal functions Report mouth lesions, dyspnea, dysuria | Rheumatrex |
| Sodium polystyrene sulfonate | Hyperkelemia to decrease k+ | N/v, constipation, anorexia, gastric irritation, hypokalemia (muscle weakness, fatigue) | Monitor k+ level (3.5-5.2) Low sodium diet No potassium rich foods (melons, bananas, oj, potatoes) | Kayexelate |
| Ritonavir | Treats HIV in combination with other antiretrovirals | Abdominal pain, anorexia, n/v/d, weakness, decreased bone density, liver toxicity | Administer with meals Monitor glucose, cholesterol, wt, liver function Monitor for liver toxicity. Avoid illness exposure. Increase wt bearing exercise Monitor for fat redistribution (thin extremities, increase abd fat, buffalo hump | Norvir |
| Metronidazole | Trichomoniasis C diff Amebiasis | Metallic taste, headache, dark urine, peripheral neuropathy, insomnia, dry mouth, GI distress | Give on empty stomach Neuro checks, weight, fluid volume balance Avoid alcohol for 24hrs after treatment | Flagyl |
| Clopidogrel | Decreases MI and stroke Inhibits platelet aggregation | Diarrhea, rash, itching, abd pain, headache, chest pain, dizziness, muscle aches, liver failure | Report fever, chills, sore throat, bleeding Report blood in stool Monitor for uri NO GARLIC, GINGER, GINGKO | Plavix |