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Brain tumors

Tumors inside brain substance Gliomas and vascular tumors
Tumors outside brain substance Meningiomas and cranial nerve tumors
Malignancy of astrocytomas Moderately malignant grades I and II (glia cells and astrocytes)
Malignancy of glioblastomas Highly malignant and invasive grade III and IV(primitive stem cell)
What is a meningioma? endothelial cells, 20% tumors, benign and encapsulated
What is a neuroma? 5% tumors, benign or low-grade malignancy, encapsulated
What is a vascular tumor? 3% tumors, benign, overgrowth of arteries and veins
What is a pituatary adenoma? 10% tumors, benign
What are the local destructive effects of a tumor? accumulation of metabolites, displacement of structures, obstruction of CSF flow and effects of edema and ICP on cerebral function
Symptoms of frontal lobe tumor memory deficit, personality and judgment changes, visual disturbances, seizures
Symptoms of parietal lobe tumor speech disturbances (if on dominant hemisphere), inability to write, spatial disorders
Symptoms of occipital lobe tumor seizures, blindness
Symptoms of temporal lobe tumor seizures, dysphagia
Symptoms of metastatic tumors headache, n/v
Symptoms of thalamus tumor headache, nausea, vision disturbances, papilledema, nystagmus, DI
Symptoms of cerebellopontine tumors tinnitus, vertigo, deafness
Symptoms of brainstem tumor headache, drowsiness, vomiting, ataxic gait, facial muscle weakness, hearing loss, dysphagia, crossed eyes, hemiparesis
Symptoms of a spinal cord tumor depends on nerve
Diagnosis of brain tumor MRI, CT, PET, LP, EEG, brain scan, cerebral angiography, myelogram
Pharmacologic treatment BCNU, methotrexate, corticosteroids
Side effects of cranial surgery seizures, DI, increased ICP, CSF leak
Temozolamide (Temodar) 1st oral chemotherapeutic agent that crosses blood/brain barrier
Created by: leigh_86us