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bio test 3
| Question | Answer |
|---|---|
| What is necessary to normal growth, development, and repair of the body? | cell division |
| What is thee sequence of steps that a cell undergoes in order to divide? | the cell cycle |
| What are the stages of the cell cycle? | interphase, mitosis, and cytokenisis |
| Mitosis | the segregation and separation of duplicated chromosomes during cell division |
| Cytokinesis | physical division of a cell into two daughter cells |
| What phase does mitosis take place in? | several phases, each is important to properly segregate chromosomes |
| What ensures accurate progression through the cell cycle? | cell cycle checkpoints |
| What do cell cycle checkpoints do? | fix mistakes that occur such as DNA damage |
| What happens if there aren't proper checkpoints? | cells can get DNA damage during cell division and pass these defects to daughter cells |
| What can unregulated cell division cause? | cancer |
| What do cancer cells lose the ability to do? | regulate cell division, reproduce uncontrollably, and then sometimes form tumors |
| How does chemo work? | interfering with parts of the cell cycle |
| How does taxol work? | interfering with separation of sister chromatids by microtubules during mitosis |
| metastasis | spread of cancer form one location in body to another |
| tumor | mass of cells resulting from uncontrolled cell division |
| apoptosis | programmed cell death, cellular suicide |
| interphase | stage of cell cycle when cells spend time preparing for cell division |
| DNA is replicated when in the cell cycle? | S |
| DUring what stage of the cell cycle do sister chromatids seperate from each other? | anaphase |
| During what stage of the cell cycle are sister chromatids initially produced? | S phase |
| Which checkpoint prevents a normal cell from completing its cell cycle if it doesn't accurately replicate its DNA? | interphase (G2-M) |
| mutation | change in nucleotide sequence of DNA |
| germ-line mutation | mutation occuring in gametes, passed on to offspring |
| somatic mutation | mutation occurs in a body (nongamete) cell, not passed to offspring |
| functional protein | this protein regulates cell cycle |
| nonfunctional protein | has an altered shape making it dysfunctional and unable to regulate the cell cycle, cancer can result |
| mutagen | physical or chemical agents that cause mutations |
| carcinogen | any chemical agent that causes cancer by damaging DNA |
| proto-oncogene | gene that codes for a protein that helps cells divide normally |
| tumor suppressor gene | gene that codes for proteins that check cell cycle progression |
| oncogene | mutated and over active form of a proto-ocogene, drive cells to continually divide |
| benign tumor | noncancerous tumor that won't spread |
| malignant tumor | cancerous tumor that spreads through body |
| Are mutations that occur in somatic (body) cells inherited by offspring? | no |
| Are mutations that occur in germ (sperm or egg) cells inherited by offspring? | yes |
| BRCA mutations in women | mean they have a higher risk of developing cancer from an earlier age |
| diploid | having two copies of every chromosome |
| homologous chromosomes | pair of chromosomes both containing the same gene |
| phenotype | visible features of an individual |
| genotype | the particular genetic makeup of an individual |
| gametes | specialized reproductive cells that carry one copy of each chromosome |
| haploid | having one copy of each chromosome |
| meiosis | specialized nuclear division that generates genetically unique haploid gametes |
| zygote | cell that is capable of developing into adult organism, formed when an egg is fertilized by a sperm |
| embryo | when a zygote undergoes cell division to form a multicellular structure |
| recombination | an event in meiosis when maternal and paternal chromosomes pair and physically exchange DNA segments |
| independent assortment | alleles of different genes are distributed independently of one another during meiosis |
| recessive allele | allele that reveals itself in the phenotype only if a masking dominant allele is not present |
| heterozygous | having two different alleles |
| homozygous | having two identical alleles |
| carrier | someone who is heterozygous and can pass recessive genes without showing any of its effects |
| Are humans diploid or haploid? | diploid, we have two copies of nearly every gene in our body cells |
| What are different versions of the same gene called? | alleles |
| How do alleles occur? | they arise from mutations that change the nucleotide sequence of the gene |
| What is the genotype of a person with CF? | homozygous recessive |
| antibiotics | chemicals that either kill bacteria or slow their growth by interfering with the function of essential bacterial cell structures |
| binary fission | type of asexual reproduction in which one parental cell divides into two |
| evolution | change in allele frequencies in a population over time |
| fitness | relative ability of an organism to survive and reproduce in particular environment |
| natural selection | differential survival and reproduction of individuals in response to environmental pressure that leads tochange in allele frequencies in population |
| adaption | process where populations become better suited to environment |
| directional selection | type of natural selection where organisms on one end of spectrum are favored by environment |
| stabilizing selection | type of natural selection where organisms in middle of spectrum are favored by the environment |
| diversifying selection | type of natural selections where organisms at both ends of the spectrum are favored by the environment |
| How do bacterial populations, that reproduce asexually, acquire genetic variation? | by mutation and gene transfer |
| How do populations of sexually reproducing organisms acquire genetic variation? | by mutation and meiosis and fusion of gametes |
| Genetic variation in a population gives rise to what in a population? | corresponding phenotypic variation |