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RNA Virus(sect.2.3)

Influenza Virus-The Avian Flu (The Bird Flu)

QuestionAnswer
The Avian (Bird) Flu H5N1 (Avian flu)
First cases of Avian Flu March-1997, (H5N1) first detected in HK chickens and 6,800 birds died. May 19, 1997; 3-yr-old boy hospitalized with (H5N1). 18 total cases, 6 deaths, reported
Public health risk from (H5N1) Avian Flu Reassormnt could link high trans. =high mortality & cause of pandemic. H5N1 first surfaced in HK in 97-jumped species barrier, killing 6. H5N1 is widespread in ducks in S. China. Has become more lethal to mice between 99-02. Can infect pigs & cats.
Why hasn't a reassortment of H5N1 taken place yet? Avian flu-reassortment studies show: *Mix H5N1 and human influenza in the lab helps determine how dangerous a hybride would be. *Infect vero cells w/bothH5N1 and a currently circulating human strain (H3N2 & H1N1).
Why hasn't a reassortment of H5N1 taken place yet? (Cont.) Any viable hybrid would be inoculated into mice. *Those cause disease would be inoculated into ferrets, (simular to human subsept.). *Any strain that is pathogenic in ferrets/and also spreads from sick animal to healthy animal could be pandemic strain.
Controversy of Avian Flu vaccine Could create a pandemic strain that escapes into the world and used for terriorism.
The National Strategy for Pandemic Influenza Guides our preparedness and response to an influenza pandemic.
What is the first guide for prepardness and response to an influenza pandemic. Stopping, slowing or otherwise limiting the spread of a pandemic in U.S.
What is the second guide for prepardness and response to an influenza pandemic. Limiting the domestic spread of a pandemic, and mitigating diesease, suffering and death.
What is the third guide for prepardness and response to an influenza pandemic. Sustaining infrastructure and mitigating impact to the economy and the funtioning of society.
Created by: mdnlght
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