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ONCOLOGY-1400

Oncology-Cancers of the Blood-Alison Miles

QuestionAnswer
Leukemia any malignant blood disorder in which leukocytes (WBC), usually in an immature form, proliferate (grow) unregulated; often with decreased erythrocytes (RBC) and platelets
4 Types of Leukemia ALL, CLL, AML, CML
ALL (Acute Lymphocytic Leukemia) onset usually younger than 5, rarely over 15; increased lymphocytes, decrease RBC and platelets
CLL (Chronic Lymphocytic Leukemia) onset older than 40; increased lymphocytes, normal or low RBC and platelets; most common type in adults
AML (Acute Myelogenous Leukemia) all age ranges; decrease in myeloid formed cells (monocytes, granulocytes, RBC and platelets)
CML (Chronic Myelogenous Leukemia) onset older than 20, increasing with age; genetic link, same as AML but greater number of normal cells
Leukemia signs and symptoms fatigue from anemia (low RBC, tired, pale, fragile, cold, low o2); infections (low/immature WBC); bruising (low platelets); spleen & lymph enlargement (from infection); nose bleeding, mouth and GI tract (low platelets)
Leukemia treatment chemotherapy, bone marrow transplant, stem cell transplant
Multiple Myeloma malignancy involving plasma cells or B-lymphocyte cells in the bone marrow; poor prognosis w/estimated survival of 1-5 years
Multiple Myeloma treated by steroids/chemo, bone marrow transplants; treatment doesn't cure, but prolongs life
Multiple Myeloma Pathophysiology osteoclast breaks down bone cells, abnormal plasma cells release osteoclast, release proteins that damage kidneys and reduce production of antibodies
Created by: txladybug70