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DNA Virus(sect 3.1)

Viral Hepatitis

QuestionAnswer
Hepadnavirus both dbl and sgl stranded DNA, show a decided tropism for the liver, enveloped
Hepatitis Inflammation of the liver, producing swelling, tenderness and sometimes perminent damage.
Cause of Hepatitis by at least 6 different Hepadnaviruses; HAV, HBV,HDV, HEV, HGV, and there could be more.
Non-viral Hepatitis may be caused by chemicals, drugs or alcohol. Every year, more than 600K Americans become newly infected with viral hepatitis, only 10% of these cases are reported.
Describe the Liver Located behind lower ribs on right side.*weighs 3lbs, roughly the size of a football, *All blood leaving the stomach & intestine passes through the live before going to the rest of the body.
Filtering Functions of the Liver Removes and destroys toxins. Stores vitamins, minerals, and sugars. Manufactures proteins involved in clotting, immunity, etc.
Are HAV, HBV, and HCV related to each other NO
Characteristics of HAV Viral Agent: Picornaviridae; non-enveloped icosahedron, ssRNA. Tans: Fecal or Oral. Vaccine: Inactivated & attenuated vacc. available & immune globulin. Mildest form and can not become Chronic
Characteristics of HBV Viral Agent: Hepadnaviridae, enveloped icosahedral dsDNA. Tansmission: Blood, ses, can be spread to fetus. Vaccine: Recombinant vacc. produced by yeast. Can become chronic 10% of the time and 90% before the age of 1.
Characteristics of HCV Viral Agent: Flavivirdae, enveloped icosahedron ssRNA. Transmission: Mainly blood, not easily spread through sex or fetus. Vaccine: NONE, Can become Chronic 80% of the time.
HAV Prevention Handwashing, inactivated and attenuated vaccine available, immune globulin
Created by: mdnlght
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