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Psych meds
| Question | Answer |
|---|---|
| Lab test for clozapine (Clozaril) | WBC due to agranulocytosis |
| irreversible involuntary movements (face, lips, tongue, arms, legs) | tardive dyskinesia |
| muscle rigidity, hyperpyrexia, agitation, tachycardia, hypotension, diaphoresis; extreme cases---coma and death | serotonin syndrome |
| fluphenazine (Prolixin) | 1st generation antipsychotic |
| T or F? A client who takes an SSRI with an MAOI is at risk for hypertensive crisis? | false; at risk for serotonin syndrome |
| methylphenidate drug class | ADHD stimulant |
| disulfiram (Antabuse) | alchohol antagonist |
| buspirone drug class | nonbenzo anxiolytic |
| lithium drug class | anti-manic |
| rigidity, hyperpyrexia, unstable/elevated BP, diaphoresis, pallor, delirium | NMS |
| neurotransmitter: complex movements, motivation, cognition, regulation of emotional responses | dopamine |
| neurotransmitter: mood, sleep, sex, temperature regulation | serotonin |
| neurotransmitter for: attention, learning, memory | norepinephrine |
| haloperidol (Haldol) drug class | 1st generation antipsychotic |
| aripiprazole (Abilify) drug class | 3rd generation antipsychotic |
| clozapine (Clozaril) drug class | 2nd generation antipsychotic |
| doxepin (Sinequan) | TCA |
| What time of day does pt take: TCAs? SSRIs? | TCA=HS, SSRI=AM |
| fluphenazine (Prolixin) | 1st generation antipsychotic |
| lurasidone (Latuda) | 2nd generation antipsychotic |
| olanzapine (Zyprexa) | 2nd generation antipsychotic |
| quetiapine (Seroquel) | 2nd generation antipsychotic |
| ziprasidone (Geodon) | 2nd generation antipsychotic |
| risperidone (Risperdal) | 2nd generation antipsychotic |
| chlorpromazine (Thorazine) | 1st generation antipsychotic |
| fluoxetine (Prozac) | SSRI |
| citalopram (Celexa) | SSRI |
| paroxetine (Paxil) | SSRI |
| sertraline (Zoloft) | SSRI |
| venlafaxine (Effexor) | SSNRI |
| duloxetine (Cymbalta) | SSNRI |
| foods that may affect lithium | caffeine-may lower lithium level; sodium-avoid major changes in salt intake (no sudden increase/decrease) |
| St John's Wort | herbal for depression |
| foods to avoid with St. John's Wort | tyramine foods; can cause hypertensive crisis |
| alprazolam (Xanax) | benzodiazepine anxiolytic |
| lorazepam (Ativan) | benzodiazepine anxiolytic |
| chlordiazepoxide (Librium) | benzodiazepine anxiolytic |
| clonazepam (Klonopin) | benzodiazepine anxiolytic |
| buspirone (Buspar) | nonbenzodiazepine anxiolytic |
| methylphenidate (Ritalin) | ADHD stimulant |
| amphetamine mixture (Adderall) | ADHD stimulant |
| foods to avoid with ADHD | caffeine, sugar, chocolate |
| tacrine (Cognex) | anti-dementia (mild to moderate dementia) |
| lab test for Cognex | LFTs (usually every 1-2 weeks d/t med increases liver enzymes; rarely prescribed) |
| donepezil (Aricept) | anti-Alzheimer's (early to moderate Alzheimers) |
| mamatine (Namenda) | anti-Alzheimer's (moderate to severe Alzheimer's) |
| varenicline (Chantix) | nicotine receptor agonist |
| disulfiram (Antabuse) | alcohol antagonist |
| methadone | opioid agonist |
| naloxone (Narcan) | opioid antagonist |
| valerian | herbal used for insomnia, ADHD, anxiety, depression |
| foods to avoid with MAOIs | tyramine foods; can cause hypertensive crisis |
| nortriptyline (Pamelor) | TCA |
| dry mouth, constipation, urinary hesitancy or retention | anticholinergic effects |
| EPS | acute dystonia, pseudoparkinsonism, akathisia |
| acute muscular rigidity and cramping, a stiff or thick tongue with difficulty swallowing, and, in severe cases, laryngospasm and respiratory difficulties | acute dystonia |
| shuffling gait, mask-like faces, muscle stiffness (continuous) or cogwheeling rigidity (ratchet-like movements of joints), drooling, and akinesia (slowness and difficulty initiating movement) | pseudoparkinsonism |
| intense need to move about; characterized by restless movement, pacing, inability to remain still, and the client’s report of inner restlessness | akathisia |
| treatment for EPS | lowering the dosage of the antipsychotic, changing to a different antipsychotic, or administering anticholinergic medication or Benadryl |
| A decrease in which neurotransmitter has been implicated in seizure disorders? | GABA |
| disulfiram (antabuse) used concurrently with alcohol will cause what? | acetaldehyde syndrome |
| N/V, weakness, sweating, palpitations, hypotension; can progress to resp. depression, CV suppression, seizures, death | acetaldehyde syndrome symptoms |
| action of antipsychotic meds | block dopamine |
| 1st gen antipsychotics affect positive or negative symptoms? | positive |
| 2nd gen antipsychotics affect positive and/or negative symptoms? | positive and negative |
| 3rd gen antipsychotics affect positive and/or negative symptoms? | positive and negative; can also improve cognitive functioning |
| 3 or more of these symptoms are criteria for metabolic syndrome | obesity, HTN, hyperglycemia, hyperlipidemia |
| action of TCAs? | blocks serotonin and norepinephrine |
| action of SSRIs? | blocks serotonin reuptake |
| action of SSNRIs? | blocks serotonin and norepinephrine |
| action of benzos? | mediation of GABA |
| action of Buspar? | partial agonist activity at serotonin receptors |