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Rheumatoid Arthritis
| Term | Definition |
|---|---|
| What is RA? | A common connective tissue disease Chronic, Progressive, Systemic inflammatory autoimmune disease, affects primarily synovial joints Transformed autoantibodies (rheumatoid factors IgG IgM types) form and attack healthy tissue causing inflammation |
| Early signs | Joint stiffness, Swelling, Pain, Fatigue, Weakness, Anorexia, Paresthesias |
| Late signs | Deformities, Moderate to severe pain, Morning stiffness, Anemia, Weight loss, Severe fatigue, Subcutaneous nodules, Peripheral neuropathy, Vasculitits, Pericarditis, Periungual lesions, |
| Sjogren's Syndrome | Dry eyes, Dry mouth, Dry vagina |
| Labs | Rheumatoid factor, Antinuclear antibody titer, ESR, Serum complement (C3 and C4), Serum protein electrophoresis, Serum immunoglobins |
| Diagnostic Screenings | X-ray, CT, Arthrocentesis, Bone scan |
| What are the priority collorative problems for patients with RA? | *Chronic inflammation and pain *Potential for decreased mobility *Potential for decreased self-esteem image |
| Managing chronic inflammation and pain | DMARDs -Disease Modifying Antirheumatic Drugs NSAIDs BRMs - Biological response Modifiers Glucocorticoids Immunosuppresive agents |
| DMARDs | Disease Modifying Antirheumatic Drugs Methotrexate - Cytotoxic Immunosuppressant |
| BRMs | Biological Response Modifiers - reduce signals for the immune system to cause inflammation |
| Nonphamacologic pain management interventions | Adequate rest Proper positioning Ice/Heat Self-management/Autonomy Management of fatigue Enhance body image |