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Env Toxicology
Question | Answer |
---|---|
Define pharmacology. | The study of drug action. |
Define toxicology. | The study of chemicals which exert adverse effects from unintentional exposure. |
What is a drug? | A chemical which exerts a usually beneficial effect on a living organism. |
Dose is usually expressed as what in environmental toxicology? | Exposure. |
Define toxicodynamics. | The site and mechanism of the toxic effect. |
Define toxicokinetics. | The movement of the toxic chemical. Includes: 1. Adsorption 2. Distribution 3. Storage 4. Metabolization 5. Excretion |
What are xenobiotics? | Chemicals foreign to the ecosystem, which are usually artificial. |
Who was Paracelsus? | The father of toxicology |
Summary of the pre-paracelsus era. | Characterization and cataloguing. |
Summary of the paracelsus era. | Dose concept; good and bad effects not always related; scientific method. |
What post-paracelsus event led to the formation of environmental toxicology? | the silent spring caused by DDT in 1962. |
What is a descriptive toxicologist? | They do dose testing |
What is a mechanistic toxicologist? | They study the mechanisms of toxic effects |
What is a regulatory toxicologist? | They use descriptive and mechanistic toxicology to manage risks |
What is a phytotoxin? | A toxin from a plant |
Give an example of a phytotoxin. | Yew trees produce taxol, which inhibits microtubule breakdown therefore stopping cell replication |
What is a mycotoxin? | A fungal toxin |
Give an example of a mycotoxin. | psilocybin from shrooms |
What is a zootoxin? | A toxin from an animal |
Differentiate between the two types of zootoxins. | Venom is for attack and poison is for defense |
What is a bacteriotoxin? | A toxin from a bacterium. |
Give an example of a bacteriotoxin. | Clostridium botulinum |
Give two examples of xenobiotics | DDT and TCE |
What does DDT stand for | dichlorodiphenyltrichloroethane |