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PharmCh18
| Question | Answer |
|---|---|
| Whan a Pt. has experienced infiltration of a peripheral infusion of dopamine, the nurse knows that injectingthe a - blocker phentolamine (regitine) will result in | local vasodialation |
| which statement is most correct for a Pt. taking b- blocker? | weaning off the medication is necessary to prevent rebound hypertension |
| has a new prescription for b1 blockers will keep in mind that those drugs may result in ? | bradycardia |
| A Pt. who has had a recent MI may be placed on which of the following drugs for its cardioprotective effects? | metoprolol ( lepressor) |
| adrenergic sympatomometic = | positive everyting |
| adrenergic beta blockers = | negative everything |
| what will happen if if b- blocker medications are discontinued abruptly? | rebound hypertension or chest pain |
| what should a Pt. report to their physician on b- blocking drugs? | weight gain more than 2 lbs a day or 5 lb. within 1 week |
| what medications should be avoided because of possible interactions? | OTC |
| what med should be titrated? | coreg |
| alpha- blockers may percipitate ? | hypotension |
| beta blockers may percipitate? | bradycardia, hypotension, heart block, HF |
| What med is a alpha 2 adrenergic agonists? | clonidine (catapres) |
| What med are used to treat gluacoma? | betaxolol, cartelol, timolol |
| what meds are anti arrhythmic agents? | acetbutolol( sectral), esmolol ( brevibloc), sotalol ( betapace) |
| what prevents MI ? | atenolol, metaprolol, timolol |
| what med is most popular in post MI Pt.? | metaprolol ( lopressor) |
| what med is used to to help with hypertension and and CHF? | carvediol ( coreg) |
| which beta blocker med was the prototype? | propanolol ( inderal) |
| what does propanolol helo with? | decrease hr, decrease cardiac output, decreases tremors, help with migraines |
| what should be done with Pt. who overdose on b- blockers? | empty stomach - induce emesis or gastric lavage |
| what is the reversal agent of b- blocker meds? | atropine |
| ADE of beta- blockers? | dry mouth, rash, alopecia, mental depression, av blocker |
| beta blockers that block both beta1 and beta 2 receptors? | nonspecific Beta Blockers |
| located primarily on smooth muscle of bronchioles and blood vessels? | beta 2 receptors |
| what receptor is located in primarily in the heart ? | beta 1 receptors |
| what do beta blockers do ? | block stimulation of beta- receptors in the SNS |
| what is the action of beta 1 ? | reduces SNS stimulation of the heart, decreases HR |
| what was alpha- adrenergic blockers used for ? | HTN, BPH, peripheral vascular conditions, migraines |
| ADE of alpha blocker ? | palpatations, edema tachycardia, orthostatic hypotension |
| what do alpha adrenergic blockers do? | prevent norepinephrine, from producing sympathetic responses |
| what are adrenergic blockers also known as? | adrenergic antagonists, sympatholytics |
| why are they called sympatolytics? | because they "lyse" or inhibit SNS stimulation |
| drugs with a specific receptor affinity that produce a "mimic" response | agonists |
| paroxysmal chest pain caused by myocardial ischemia | angina |
| drugs that bind to adrenergic receptors and inhibit or block the action of neurotransmitters | antagonists |
| term applied to b- blockers to inhibit stimulation of the heart by circulating catecholamines | cardioprotective |
| b-blocking drugs that are selective for b1 - adrenergic receptors | cardioselective b- blockers |
| irregular heart rythms almost always called arrhythmias in clinical practice | dysrhythmias |
| leaking of fluid from the blood vessels into the surrounding tissue as in the case of an infiltrated IV fusion | extravastion |
| the production of glucose from glycogen in the liver which is reduced by b- blockers | glycogenolysis |
| paradoxical action of soe b- blocking drugs that mimics the action of the SNS | intrinsic sympatomimetic activity |
| chemical attraction of a substance to lipid or fat molecules | lipophilicity |
| b-blocking drugs that block both b1 and b2 adrenergic receptors | nonselective b-blockers |
| abnormally low BP that occurs when a person assumes a standing position from sitting or lying position | orthostatic hypotension |
| drugs used to treat postpartum and postabortion bleeding caused by uterine relaxation and enlargement | oxytocics |
| another name for adrenergic antagonists | sympatholytics |
| system classifying antidysrhytmic drugs | Vaughn williams classification |
| what do alpha-adrenergic cause? | vasodilation, lowers BP, miosis, supressed ejaculation |
| what do you do when overdose has happened from alpha-blockers? | emppty stomach, and give activated charcoal to bind with drug |
| treatment in in angina does what? | decreases myocardial contractility, decrease cardiac output, decrease heart rate |
| treatment in hypertension does what? | reduces cardiac output, inhibits production of renin |
| treatment in MI does what? | decrease mortatlity rate |