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Vocabulary #8
Question | Answer |
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Steroidogenic acute regulatory protein (stAR) | a protein that mediates the transport of intracellular cholesterol across the inner mitochondrial membrane. |
Cushing's syndrome | excessive cortisol release from the adrenal cortex that is characterized by high blood glucose levels. |
Stressor | a chemical, biological or environmental agent that stimulated the release of stress hormones. |
Glucocorticoids | steroid hormones released from the zona fasciculata of the adrenal cortext such as cortisol that increase blood glucose levels during stress, prevent water loss from cells, and have anti-inflammatory activity. |
Mineralocorticoids | hormones released from the zona glomerulosa of the adrenal cortext such as aldosterone that regulate fluid and salt balance. |
Androgens | hormones released from the zona reticularis of the adrenal cortex such as dehydroepiandrosterone that act as neurosteroids and form the basis for production of sex steroids. |
Catecholamines | hormones produced by the adrenal medulla such as epinephrine, norepinephrine and dopamine that are released into blood in response to sympathetic stimulation. These hormones are produced by the chromaffin cells of the adrenal medulla using tyrosine. |
Addison’s disease | a dysfunction of the adrenal coretx resulting in decreased blood levels of mineralocorticoids and glucocorticoids |
Albumin | a plasma protein involved in transport of glucocorticoids. |
Corticosteroid-binding globulin (CBG) | synthesized in liver and utilized in transport of corticosteroid by binding to most of the cortisol and corticosterone in circulation; also called transcortin |
P450scc ( Cholesterol side-chain cleavege enzyme) | Is a mitochondrial enzyme that facilitates conversion of cholesterol to pregnenolone. |
Sex hormone-binding globulin (SHBG) | synthesized in liver, transport testosterone and estrogen through the blood |
Stress Response | the body's attempt to return to homeostasis in response to a stressor |