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Actions on Body 2

Chap. 35

QuestionAnswer
THE TRANSPORTATION OF A DRUG FROM ITS SITE OF ABSORPTION TO ITS SITE OF ACTION DISTRIBUTION
WHEN A DRUG ENTERS THE BLOODSTREAM, IT IS FIRST CARRIED WHERE? TO THE MOST VASCULAR ORGANS --LIVER, KIDNEYS, AND BRAIN
BIOTRANSFORMATION IS ALSO CALLED.. DETOXIFICATION OR METABOLISM
A PROCESS BY WHICH A DRUG IS CONVERTED TO A LESS ACTIVE FORM BIOTRANSFORMATION
MOST BIOTRANSFORMATION TAKES PLACE WHERE? IN THE LIVER
WHEN MAY BIOTRANSFORMATION BE ALTERED IF A PERSON IS VERY YOUNG, IS OLDER, OR HAS AN UNHEALTHY LIVER
THE PROCESS BY WHICH METABOLITES AND DRUGS ARE ELIMINATED FROM THE BODY EXCRETION
MOST METABOLITES ARE ELIMINATED BY... THE KIDNEYS IN THE URINE
OTHER ROUTES BY WHICH METABOLITES ARE ELIMINATED ARE: FECES, THE BREATH, PERSPIRATION, SALIVA, AND BREAST MILK, AND SOME DRUGS ARE EXCRETED IN AN UNCHANGED FORM VIA THE RESPIRATORY TRACT
WHAT FACTOR DIMINISHES THE EFFICIENCY IN WHICH DRUGS ARE EXCRETED? AGE
TRUE OR FALSE. OLDER PEOPLE REQUIRE A MUCH LARGER DOSE OF A DRUG THAN A YOUNGER ADULT? FALSE. REQUIRE A MUCH SMALLER DOSE
WHY WOULD AN OLDER PERSON REQUIRE A SMALLER DOSE OF A DRUG THAN A YOUNGER PERSON? BECAUSE THE DRUG AND IT'S METABOLITES MAY ACCUMULATE IN THE BODY
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