Save
Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't know (0)
Remaining cards (0)
Know (0)
0:00
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

PARASCI_L8

Endocrine Disorders

QuestionAnswer
complex syndrome involving metabolic dysfunction, sexual immaturity and growth retardation hypopituatarism
enlargement of thyroid gland goitre
thyroid hormone secretion insufficient for metabolic needs, thyroid gland enlarges to compensate, & overcome mild - moderate impairment simple goitre
affects regional groups of people where soil and food iodine are low enemic goitre
developing brain major target, crosses blood-brain barrier in foetal development, affects growth & development, metabolism, body temperature and heart rate triiodothyronine (t3)
regulates many of the body's metabolic functions, basal metabolic rate can increase by 60-100% when large amounts of T4 present, principle function to stimulate O2 consumption, generates body heat thyroxine (t4)
metabolic imbalance due to increased secretion of T4 and T3 stimulating protein, lipid and carb metabolism, Hyperthyroidism
Autoimmune disorder increasing t4 production manifesting as hyper-metabolism, toxic goitre, exopthalmos graves disease
extreme & life threatening form of graves disease, hyperthermia 41C<, tachycardia, heart failure, delirium, coma thyroid storm (thyrotoxic crisis)
hypothalamic, pituatary or thyroid insufficiency,/resistance to thyroid hormone. hypothyroidism
autoantibodies destroy thyroid gland tissue, can lead to goitre chronic autoimmune thyroiditis (Hashimotos thyroiditis)
severe adult hypothyroidism: non pitting oedema seen in facial puffiness and thick tongue Myxedema
untreated congenital hypothyroidism; thyroid gland non-funcitonal or absent cretinism
characteristic orange-peel skin with oedematous appearance pretibial myxedema
acute hypothyroidism causing hypotension, hypoglycaemia, hypothermia and LoC Myxedema coma
excessive glucocorticoids due to tumore or large amounts of glucorticoids administered in chronic inflammatory conditions cushing syndrome
deficiency in adrenocortical secretions addisons disease
secretes digestive juices acini
secretes hormones into blood islets of langerhans
secretes insulin and amylin beta cells
secretes glucagon alpha cells
promote glucose uptake by target cells & glucose storage, prevents fat & glycogen breakdown, inhibits gluconeogenesis insulin
maintains BGL between meals/fasting, exerts main action in liver, increases plasma glucose via glycogenolysis & gluconeogenesis glucagon
90-95% of sufferers, more common in younger people but can occur at any age Type 1A immune-mediated diabetes mellitus
much less common, no autoimmune involvement Type 1B idiopathic diabetes mellitus
hyperglycaemia with insulin resistance- no destruction of beta cells Type 2 diabetes mellitus
glucose intolerance during pregnancy of women with no history of diabetes gestational diabetes
excessive hunger polyphagia
excessive thirst polydipsia
excessive urination polyuria
sudden onset, cool, pale moist skin, normal RR, breath odour, weak rapid pulse, uncoordinated headache, irritable, poor conc. seizures hypoglycaemia
slower onset, warm, feverish, red & dry skin, deep and rapid breathing, possible kussmaul breathing, possible acetone breath, tachycardic, nausea & vomiting, abdo pain, hypotension, decreased LoC hyperglycaemia
insulin inhibits lipolysis, & release of free fatty acids, insufficient insulin -> hyperglycaemia and lipid mobilisation -> ketosis occurs fatty acids released and converted to ketones, diabetic ketoacidosis
hyperglycaemia pulling water from body cells (incl brain) hyperglycaemia hyperosmolar state
Kussmaul respiration, nausea & vomiting, abdo pain, fatigue, thirst, sweet smelling breath, confusion, drowsiness, hypotension, tachycardia Symptoms of DKA
Usually present dehydrated with stupor or in coma, unconscious, polyuria (weeks), profound dehydration, hypotension (later), tachycardia symptoms of HHS
disorder of water metabolism; deficient ADH secretion or renal resistance to ADH diabetes insipidus
deficiency of ADH acute onset neurogenic diabetes insipidus
resistance of renal tubules to ADH nephrogenic diabetes insipidus
caused by excessive fluid intake, primary polydipsia, psychogenic diabetes insipidus
metformin (glucophage), chloropropamide, Glycburide (diabeta), Glipizide (glucotriol) Oral meds for type 2 diabetes
actrapid (humalog/novalog), long acting (levemir/lantus), premixed (regular insulin + NPH) Insulin meds for type 1 diabetes
Created by: 1092422624234171
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards