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Pathology 1 lecture

Eight major pathologic categories/processes into which disease can be placed Inflammation, neoplasia, hemodynamic/vascular, environmental/nutritional/ genetic/development, infectious, immunologic, endocrine/metabolic
List the 3 main mechanisms ( underlying cause) of cell injury and desribe deficiency and examples of it. Deficiency, Intoxication, and Trauma. 1. Deficiency –lack of necessary substance (nutrition, air, ect) Ex O2 hypoxia (state when cell is without O2) or ischemia (oxygen deprivation due to lack of blood flow)
List the 3 main mechanisms ( underlying cause) of cell injury and desribe Intoxication and examples of it. 2. Intoxication – Overabundance of something. (nutrition, water, ect) Interferes with cell function. Endogenous (metabolite, genetic defect) or exogenous (infectous agent, chemicals, drugs). Too much O2 can kill anaerobic cells ect.
List the 3 main mechanisms ( underlying cause) of cell injury and desribe trauma and examples of it. 3. Trauma – Loss of structural integrity. Hypothermia, hyperthermia (denature proteins) Infections rupture or lyse the cell. Ex. Bacteria that can lyse cells, or physical breaking of cells in injury.
What are the 6 morphologically recognizable ways that cells may respond to non lethal injury. 1. Atrophy 2. Hypertrophy 3. Hyperplasia 4. Metaplasia 5. Dysplasia 6. Intracellular Storage
Define atrophy Atrophy – lose of blood to area, or inadequate nutrition.
Hypertrophy 2. Hypertrophy – Mechanical stimulus (lifting weights) growth factor (puberty)
Created by: cwj6