Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

GI regulation

Med 1

ThingAbout Thing
CCK I cells of small intestine (CCKa receptors); stimulated by: peptides, AA, and FA; action: contraction of gallbladder and relaxation of sphincter of Oddi, increase pancreatic enzyme/ HCO3, inhibits gastric emptying
Secretin S cells of duodenum; stimulated by: H+ and FA in duodenum; action: increases pancreatic and biliary HCO3, decreases gastric H+
GIP K cells of small intestine; stimulated by: FA, AA, and oral glucose; action: increase insulin secretion, decrease H+
Ach Vagus; action: M3 receptor—> Gq—> IP3/ Ca++—> H+; pumps up ECL; blocked by atropine
Gastrin G cells of stomach antrum (circulation); stimulated by: peptides and AA, stomach distention via ACh, vagus via GRP; action: CCKb receptor —> Gq—> IP3/ Ca++—> H+; activates ECL more powerfully; increases gastric mucosa
Histamine ECL cells; action: H2 receptor—> Gs—> cAMP—> H+; blocked by cimetidine
Somatostatin D cells, action: Diffusion—> Gi—> cAMP—> stop H+; inhibits ECL and G cells
Prostaglandins action: Diffusion—> Gi—> cAMP—> stop H+; inhibits ECL cells; stimulates mucus production
VIP Parasym gangs in sphincters, gallbladder, small intestine; stimulated by: distention and vagus; action: relaxation of intestinal smooth muscle (NO relaxes too)
Intrinsic factor Parietal cells of stomach fundus; stimulated by: Gastrin and Histamine via G and ECL cell, vagus via ACH; action: Vit B12 absorption in terminal ileum
Pepsin chief cells of stomach (fundus) mucous cells (antrum) as pepsinogen, stimulated by: Vagus, action: Protein digestion
Created by: JustinCo