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Pharmacology 3041
Representative Drugs
| Term | Definition |
|---|---|
| Bethanechol | Cholinergic: increases detrusor muscle tone and GI motility. Adverse Reactions: bronchospasm, hypotension, tachycardia, seizures |
| Atropine | Anticholinergic: preanesthetic; treatment of bradycardia, biliary colic, intestinal hypertonicity & muscarinic agonist poisoning. Adverse Reactions: glaucoma, tachycardia, severe bradycardia, gastric outlet obstruction, urinary retention, heat stroke. |
| Neostigmine | Cholinesterase Inhibitor: used in treatment of neuromuscular disorders such as Myasthenia Gravis Adverse Reactions: arrhythmias, bradycardia, AV block, cardiac arrest, syncope, severe hypotension, respiratory arrest/depression, bronchospasm, seizures. |
| Physostigmine | Cholinesterase Inhibitor: Adverse Reactions: cholinergic crisis, bradycardia, AV block, arrhythmias, severe hypotension, syncope, cardiac arrest, bronchospasm, respiratory depression/arrest, pulmonary edema, paralysis, seizures, hallucinations |
| Echothiophate | Cholinesterase Inhibitor: binds irreversibly to acetylcholine binding site on pseudocholinesterase; treatment of glaucoma and incr. IOP. |
| Pralidoxime | Antidote to inhibition of cholinesterase in organophosphate toxicity (reactivates cholinesterase). Adverse Reactions: cholinergic sx exacerbation |
| Edrophonium | Reversible cholinesterase inhibitor: anesthesia adjunct; neuromuscular disorders; given as challenge dose to differential diagnosis of myasthenic crisis vs. cholinergic crisis. Adverse Reactions: cholinergic rxn, arrhythmias, bradycardia, hypotension, |
| Atracurium | Neuromuscular Blocker: competitive, non-depolarizing nm blocker. Antagonizes ACh receptors on motor endplate. Adverse Reactions: Respiratory depression, apnea, malignant hyperthermia, seizures, bronchospasm, hypotension, cardiac arrest, arrhythmias |
| Pancuronium | |
| Succinylcholine | |
| Dantrolene | |
| Epinephrine | |
| Albuterol | |
| Prazosin | |
| Propanolol | |
| Baclofen | |
| Diazepam | |
| Clonidine | |
| Methyldopa | |
| Resperine | |
| Levodopa/Carbidopa | |
| Amantadine | |
| Pramipexole | |
| Bromocriptine | |
| Entacapone | |
| Selegiline | |
| Donepezil | |
| Memantine | |
| Interferon Beta | |
| Dimethyl Fumarate | |
| Mitoxantrone | |
| Phenytoin | |
| Carbamazepine | |
| Valproic Acid | |
| Phenobarbital | |
| Morphine | |
| Pentazocine | |
| Naloxone |
Created by:
JuliePritchard
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