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VIrus Module Set 7
| Question | Answer |
|---|---|
| host cell damage and cell death: | inhibition of host DNA, RNA, and protein synthesis |
| host cell damage and cell death by lysosome damage | causes release of hydrolytic enzymes into cell |
| host cell damage and cell death by alteration of plasma membrane can lead to | attack of host cell by immune system cell fusion, forming syncytium |
| host cell damage and cell death by toxicity from | high concentrations of viral proteins |
| host cell damage and cell death by formation of | inclusion bodies, which can disrupt cell structure |
| host cell damage and cell death by chromosomal | disruptions |
| host cell damage and cell death by transformation of | host cell into malignant cell |
| acute infections: | rapid onset and relatively short duration |
| persistent infections: | can last many years |
| chronic virus infection: virus... | almost ALWAYS detectable |
| chronic virus infection: during latency... | symptoms, antivirus-antibodies, and viruses are NOT detectable |
| cause of persistent infections by integration of | viral genome into host genome |
| cause of persistent infections by decrease in | antigenicity of virus |
| cause of persistent infections by mutation to | less virulent and slower reproducing form |
| defective interfering (DI) particle: | deletion mutant that CANNOT reproduce and slows reproduction of normal virus |