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HTN meds

Classification MedUse of medSEImportant
Avoid K+ ACE inhibitors “Pril” drugs Prevent conversion of angiotensin 1 to angiotensin ll. Prevents vasoconstriction Dry persistent cough Changes in taste Dizziness Fatigue NSAIDs/aspirin decrease effectiveness African Americans do not respond well Do not use wit k+ sparing diuretic Avoid k+ substitutes Rebound HTN in non compliant
ARBS “Sartan” Blocks aldosterone Blocks angiotensin ll from AT1 receptor Dizziness Fatigue Insomnia *no dry cough Less effective in African Americans Watch renal function
*P Beta blockers “Lol” Inhibits SNS Vasodilator Decrease BP Insomnia Depression Nightmares Fatigue sexual dysfunction Do not use in pts with asthma/COPD Take apical pulse before giving Rebound HTN if not compliant DM= masks hypoglycemia
Calcium channel blockers Diltiazem Verapamil Amlodipine Nifedipine Inhibits Ca across cell membrane resulting in vasodilation Decrease HR Flush Dizziness Ankle edema Bradycardia May work better for African Americans Do NOT ingest grapefruit Watch for bradycardia
Increase K+ Diuretic (loop) Furosemide Bumetanide Torsemide Promotes NaCl & H2O excretion Orthostatic hypotension Electrolyte abnormalities Usually used first Not for pts with renal issues Watch lithium levels Increase potassium intake Photosensitive
Increase K+ Diuretic (thiazides) Metolazone Hydrochlorothiazide Promotes NaCl & H2O excretion Orthostatic hypotension Hypokalemia NSAIDs can decrease effectiveness Not for pts with renal issues Watch lithium levels Increase potassium intake Photosensitive
Potassium sparing diuretic Spironolactone Trimaterene Reduces excretion of K+ Not for renal failure pts Avoid k+ Use cautiously with ACE/ ARBS
*P Cardiac glycoside Digoxin Makes heart beat stronger Dig toxicity- Anorexia N/V Diarrhea Blurred vision Decreased HR Confusion Take pulse before giving If less than 60 hold and call DR Monitor K+ Dig toxicity use digibond
Entresto Hypotension Hyperkalemia Cough Dizziness Can’t take with ACE inhibitors Must wait 36 hrs
Vasodilator Nitrates Sodium nitro Nesiritide
Relaxing smooth muscle of blood vessels Tachycardia Palpitations Edema Dizziness Restless Pts shouldn’t take nitroglycerin with viagara
Created by: Britemp