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Analgesics
Pharmacology
| Question | Answer |
|---|---|
| What are drugs that relieve pain without causing loss of consciousness? | Analgesics |
| Which opioid receptor is associated with physical dependence? | Mu receptor |
| What are examples of pure opioid agonists? | Morphine and codeine |
| What are the general adverse effects associated with opioids? | Respiratory depression, constipation, and sedation |
| What is the most commonly used opioid antagonist? | Narcan |
| What drug is used to treat opioid-induced constipation? | Methylnatrexone |
| What can happen if an agonist-antagonist opioid is administered with a pure opioid agonist? | It can antagonize analgesia |
| What is the source of morphine? | Seedpod of poppy plant |
| Confusion | |
| What is the onset time of respiratory depression after morphine is administered? | 7 minutes IV and 30 minutes IM |
| How long can respiratory depression caused by morphine last? | 4-5 hours |
| What is an effect of morphine that is useful in surgery? | Cough suppression |
| What is an adverse effect of narcan? | Seizures |
| What are common signs of morphine toxicity? | Miosis, coma, and respiratory depression |
| How long does it take for abstinence syndrome from morphine take to occur? | 10 hours after the last dose |
| How long can abstinence syndrome from morphine last if untreated? | 7-10 days |
| What should you always do before administering an opioid? | Assess V/S |
| What is Embeda? | Morphine combined with narcan; used to prevent abuse |
| Should you give morphine on a fixed schedule or PRN? | Fixed |
| True or False: You should wear gloves when handling Duragesic. | True |
| What is the drug of choice for opioid addiction? | Methadone |
| What is the trade name for hydromorphone? | Dilaudid |
| How much of a codeine dose converts to morphine in the liver? | 10% |
| Does narcan work with Buprenorphine? | No |
| Should you give Buprenorphine to a patient with hypotension? | No |
| What is the most widely prescribed drug in the US? | Hydrocodone |
| When should you assess pain when giving an opioid? | Before giving an 1 hour after if given PO; 30 minutes after if given IV |
| What is the drug of choice for MI? | Morphine |
| What drug is used for reversal of neonatal respiratory depression? | Narcan |
| What is an adverse effect of tramadol? | Suicide risk |