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Anemia Drugs
Pharmacology
| Question | Answer |
|---|---|
| What are adverse effects of oral iron supplements? | GI disturbances, staining of teeth (liquid), and toxicity |
| What are S/S of iron toxicity? | N/V, diarrhea, and shock; acidosis, gastric necrosis, hepatic failure, pulmonary edema, and vasomotor collapse |
| What are drug interactions with PO iron? | Antacids (inhibits absorption), vitamin C (promotes absorption), and tetracycline (creates mass in GI tract) |
| What are adverse effects of iron dextran? | Anaphylaxis, hypotension, headache, urticaria, and arthralgia |
| What is the IV form of iron supplementation? | Iron dextran |
| What should you do before administering the ordered dose of iron dextran? | Give a small test dose |
| What should be included in patient education about PO iron? | That it will cause black, tarry stools; not to crush it; and that it may cause nausea |
| What symptom is associated with vitamin B12 deficiency? | Red, beefy tongue |
| What is vitamin B12 necessary for? | Synthesis of DNA |
| What can a folic acid deficiency cause in a pregnant woman? | Fetal neural tube defects, cleft palate and lip |
| Which preparation of folic acid is used most commonly? | Inactive |
| Which is excreted faster: Vitamin B12 or folic acid? | Folic acid |
| Which deficiency does neurologic damage occur with: Vitamin B12 or folic acid? | Vitamin B12 |
| True or False: Hematologic effects of Vitamin B12 deficiency can be reversed with large doses of folic acid. | True |
| What is a possible adverse reaction to Cyanocobalamin? | Hypokalemia |