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Pharm def ch 18
HCC Pharm def Ch 18 - Adrenergic-Blocking Drugs
| Question | Answer |
|---|---|
| Agonists | Drugs with a specific receptor affinity that produce a "mimic" response, (p. 284) |
| Angina | Paroxysmal chest pain caused by myocardial ischemia,(p. 288) |
| Antagonists | Drugs that bind to adrenergic receptors and inhibit or block the action of neurotransmitters, (p. 284) |
| Cardioprotective | Term applied to P-blockers to inhibit stimulation of the heart by circulating catecholamines, (p. 288) |
| Cardioselective B-Blockers | Cardioselective B-blockers The B-blocking drugs that are selective for B1 adrenergic receptors. Also called B1-blocking drugs, (p. 287) |
| Dysrhythmias | Irregular heart rhythms; almost always called arrhythmias in clinical practice, (p. 288) |
| Extravasation | Leaking of fluid from the blood vessel into the surrounding tissues, as in the case of an infiltrated intravenous infusion, (p. 285) |
| Glycogenolysis | The production of glucose from glycogen in the liver, which is reduced by B-blockers. (p. 288) |
| Intrinsic sympathomimetic activity | Paradoxical action of some B-blocking drugs (e.g., acebutolol) that mimics the action of the sympathetic nervous system, (p. 288) |
| Lipophilicity | Chemical attraction of a substance (e.g., drug molecule) to lipid or fat molecules, (p. 288) |
| Nonselective B-blockers | The B-blocking drugs that block both B1- and B2-adrenergic receptors, (p. 287) |
| Orthostatic hypotension | Abnormally low blood pressure that occurs when a person assumes a standing position from a sitting or lying position, (p. 287) |
| Oxytocics | Drugs used to treat postpartum and postabortion bleeding caused by uterine relaxation and enlargement. They stimulate the smooth muscle of the uterus to contract, (p. 284) |
| Pheochromocytoma | A vascular adrenal gland tumor that is usually benign but secretes epinephrine and norepinephrine and thus often causes central nervous system stimulation and substantial blood pressure elevation, (p. 284) |
| Sympatholytics | Another name for adrenergic antagonists. (p. 284) |
| Vaughan Williams classification | System of classifying antidysrhythmic drugs, (p. 288) |