Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove ads
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Thromboembolic Drugs


What are the two steps of hemostasis? Platelet plug formation and coagulation
What are the two pathways of coagulation? Intrinsic and extrinsic
What is the action of anticoagulants? Reduce the formation of fibrin
What are the three major groups of thromboembolic drugs? Anticoagulants, antiplateletes, and thrombolytics
Is the half-life of heparin short or long? Short
How can heparin be administered? Only by IV or subQ injection
Where is the optimal site for subQ heparin injection? In the abdomen, two inches from the umbilicus
What are the adverse effects of heparin? Hemorrhage, spinal/epidural hematoma, and heparin-induced thrombocytopenia
What is the primary treatment for heparin induced thrombocytopenia? Stopping the use of heparin
When is heparin contraindicated? In patients with thrombocytopenia; uncontrollable bleeding; immediately after brain, eye, or spinal cord surgery
What are the labs that must be monitored with heparin use? aPTT and INR
What is the normal range for aPTT? 25-38 seconds
What is the normal INR range? 2-3 seconds
Does heparin increase or decrease aPTT time? Increases to 60-80 seconds
How often should the aPTT be monitored in a patient on heparin? Every 4-6 hours
What should you assess for in patients on heparin? S/S of blood loss: Hypotension, tachycardia, bruises, hematomas, headache or syncope, discolored urine. Also assess mental status and mucous membranes
What is the antidote for heparin overdose? Protamine sulfate
Describe the action of protamine sulfate. Has immediate action and last 2 hours.
How is protamine sulfate administered? Usually by IV
What are the advantages of Lovenox? It can be given at home, while heparin cannot..
What patient should never receive Lovenox? Patient in kidney failure (assess creatinine and BUN levels).
True or False: Warfarin has a delayed onset. True
How is warfarin administered? PO
What are the therapeutic uses of warfarin? Prevention of thrombus in atrial fibrillation and as prophylaxis in patients with prosthetic heart valves.
What is the antidote for warfarin overdose? Vitamin K
What should be included in patient teaching for warfarin? Use a soft bristled toothbrush
What labs should be monitored with warfarin? PT and INR
What is a normal PT range? 11-14 seconds
Does warfarin increase or decrease PT range? Increase
Should warfarin be used during pregnancy? No
What are the advantages of direct thrombin inhibitors? No anticoagulation monitoring and usually the same dose is used for all patients
Do the direct thrombin inhibitors have a reversal agent? No
What is the therapeutic use for eliquis? Prevention of stroke and systemic embolism in patient with nonvalvular atrial fibrillation
What is an example of an antiplatelet drug? Aspirin
What are the thrombolytic drugs used for? Acute MI, acute ischemic stroke, and acute massive PE
What drugs are also known as clot busters? Thrombolytic drugs
What are the 3 thrombolytic drugs available in the US? Alteplase, Reteplase, and Tenecteplase
Created by: shrewsburysd