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med knowledge 2

hydrochlorothiazide/ Microzide thiazide-effects: increase Ca2+, cholesterol, uric acid (hyperuricemia); decrease K+, Na+, mag, phosphate, hypovolemia; SJS , *hypokalemia*; glaucoma, myopia; hyperglycemia, typical diuretic --lethargy, weak, drowsiness, dizziness, hypotension, cramping;
Microzide action: inhibits Na+ reabsorption in distal tubule (excrete Na+ & water). excretion of chloride, K+, magnesium, bicarbonate
hydrochlorothiazide Microzide, Oretic
hydrochlorothiazide indications: HTN, edema associated w/ HF, renal dysfunction, cirrhosis, glucocorticoids, estrogen therapy
hydrochlorothiazide/Microzide (Oretic) contraindications: hypersensitivity (cross sensitivity w/ thiazides or sulfonamides); some products contain tartrazine; Anuria; lactation
furosemide Lasix
furosemide/Lasix diuretic (loop)
furosemide/Lasix indications: edema due to HF, hepatic, or renal disease; HTN
furosemide action: increase renal excretion of water, Na, Cl, magnesium, K+, Ca2+; effective in impaired renal fx; inhibits reabsorption of Na & Cl from loop of Henele & distal tubule
Lasix therapeutic effect: diuresis; decrease BP
furosemide/Lasix; diuretic contraindications: sensitivity to thiazides & sulfonamides may occur; hepatic coma or anuria; some products contain alcohol
furosemide/Lasix: diuretic adverse reactions: *dehydration, hypocalcemia, hypochloremia, hypokalemia, hypomgnesemia, hyponatremia, hypovolemia, met alkalosis*; APLASTIC ANEMIA, AGRANULOCYTOSIS, SJS, TOXIC EPIDERMAL NECROLYSIS, ERTHYEMA MULTIFORME; fever, blurred vision, hearing loss, tinnitus,
bumetanide/Bumex loop diuretic
bumetanide side effects SJS, toxic epidermal necrolysis; dehydration, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, hypovolemia, metabolic acidosis
mannitol Osmitrol
mannitol/Osmitrol side effects CV: transient volume expansion mannitol draws fluid from extravascular space into vascular. causes transient volume expansion & may cause pulmonary edema if renal is compromised. If renal status good, extra fluid is excreted
mannitol/Osmitrol therapeutic effect mobilizes excess fluid in oliguria renal failure or edema. ↓ intraocular or intracranial pressures. ↑ urinary excretion of toxic materials. ↓ hemolysis when used as irrigant after transuretheral prostatic resection
spironolactone Aldactone
mannitol/Osmitrol diuretic (osmotic)
spironolactone/ Aldactone diuretic- K+ sparing
spironolactone/ Aldactone side effects SJS, toxic epidermal necrolysis; hyperkalemia; breast tenderness, gynecomastia, irregular menses, deepening of voice
oxybutnynin Ditropan
oxybutynin/Detrol urinary tract antispasmodic (anticholinergic)
oxybutynin side effects urinary retention; anaphylaxis, angioedema; chest pain, tachycardia; cant see, cant pee, cant spit, cant shit; teach: ↓ ability to perspire; notify if urinary retention, persistant constipation, or plans for pregnancy; t
tolterodine Detrol
tolterodine/ Detrol urinary tract antispasmodic (anticholinergic)
tolterodine side effects headache, dizziness, dry mouth, SJS; anaphylaxis, angioedema, blurred vision, dyspepsia
bethnechol Urecholine
bethanechol/Urecholine urinary tract stimulant (cholinergic
bethanechol/Urecholine indications neurogenic bladder retention; nonobstructive bladder retention
bethanechol/Urecholine side effects heart block, syncope/cardiac arrest, bradycardia, abdominal discomfort, diarrhea, nausea, salivation, vomiting. GU: urgency; MISC: flushing, sweating, hypothermia
phenazopyridine Pyridium
phenazopyridine/ Pyridium nonopioid analgesic
phenazopyridine side effects hepatotoxicity; bright-orange urine; renal failure; rash, hemolytic anemia, methemoglobinemia
trimethoprim-sulfamethoxazole Bactrim
timethoprim-sulfamethoxazole anti infective; anti protozoal
bactrim indications: bronchitis, Shigella, ottitis media, pneumocystiis jirovecii pneumonia, UTI, traveler's diarrhea
trimethopriim-sulfamethoxazole side effects C. difficile, hepatic necrosis, nausea, vomiting, erythema multiforme, SJS/ TEN, rash, agranulocytosis, aplastic anemia, phlebitis at IV site; kericterus in neonate; cholesttic jaundice, pancreatitis
epoetin Epogen (Procrit)
epoetin/ Epogen (Procrit) antianemics; hormone
epoetin indications anemia r/t CKD; anemia secondary to AZT therapy (HIV)
epoetin/ Epogen side effects seizures, h/a, HF, MI, stroke, thromboembolic events (esp if Hgb >11); restored fertility & menses; ↑mortality & ↑ tumor growth (in cancer)
postassium chloride K-Dur
potassium chloride/K-Dur indications prevent or treat K+ deficiency
potassium chloride side effects confusion, restlessness, weakness, arrhythmias, ECG changes, abd probs—diarrhea etc; paralysis, paresthesia
Created by: vmcfarla