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anticoagulant
coumadin
| Question | Answer |
|---|---|
| What is the prototype for oral anticoagulants | Coumadin (warfin) |
| What are the most common oral anticoagulants | Coumadin (warfin), dicumarol |
| What are some common uses for oral anticoagulants (Coumadin) | prevention of venous thrombosis, atrial fibrillation prosthetic heart valves |
| What is the antidote to Coumadin | vitamin K |
| What is the normal value for PT | 1.5 - 2 X base or 18-24 seconds |
| What is the normal value for INR | 2 -3 |
| When should Coumadin NOT be used | pregnancy, low platelets |
| Why should alcoholics not use Coumadin | there is an increased risk of bleeding |
| Why can’t Coumadin (oral anticoagulant) be used during pregnancy | if crosses the placenta |
| Use caution when giving Coumadin to patients with | hemophilia, dissecting aneurysm, peptic ulcer disease, sever HTN |
| What Foods should not be eaten when taking Coumadin and why | foods high in vitamin K, b/c they can decrease anticoagulant effects |
| List foods high in Vitamin K | green leafy vegetables, cauliflower, and cabbage |
| Which drugs when taken with Coumadin will promote bleeding | heparin, aspirin, acetaminophen, sulfonamides, and parenteral cephalosporins? |
| Which drugs when taken with Coumadin will decrease the anticoagulant action | Phenobarbital, carbamezepine, dilantin, Oral contraceptives, & vitamin K supplements |
| How does smoking effect anticoagulant therapy | increases drug metabolism, so it is eliminated faster & this make pt more likely to clot |
| How long after a patient stops anticoagulants does the drug remain in the system | 5 days |
| Any time a patient on anticoagulant therapy adds/stops a drug you should | monitor PT & INR levels b/c they could change |
| Coumadin binds to | protein |
| Important client teaching for Coumadin includes | reason for continued heparin use, continued Coumadin effects 5 days after ending therapy, avoid alcohol, OTC, & herbal therapies, wear medical alert bracelet, notify all health care of use. |
| What should be monitored on patients receiving oral anticoagulants | V/S, bleeding, PT, & INR |
| What is the action of oral anticoagulants (coumadin) | inhibits synthesis of vitamin K and effect certian clotting factors |