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Anti-platelet
aspirin,plavix,pletal
| Question | Answer |
|---|---|
| How do anti-platelet medication work | prevent platelets from sticking together and that prevents clots from forming in the arteries |
| Anti-platelets work mainly in the | arteries |
| What is the prototype drug for anti-platelet drugs | aspirin (ecotrin) |
| Commonly used anti-platelet drugs include | aspirin,plavix,pletal |
| Aspirin dosage related to heart attack is usually | 81mg & enteric coated |
| Aspirin dosage related to stroke is usually | 325mg & enteric coated |
| If a patient is having symptoms of acute MI they should take | 325mg aspirin |
| The anti-platelet Pletal (cilostazol)is mainly used for | intermitten claudication b/c of its vasodilation effects |
| Intermitten claudication is | leg pain and cramps with activity that goes away with rest |
| Anti-platelets (aspirin) are mainly used for | prevention of acute MI, reinfarction after MI, prevention of ischemic stroke. |
| The anti-platelets ReoPro & Aggrastat are use to treat | acute coronary syndromes |
| Side effects of anti-platelets (aspirin) are | GI bleeding, hemorrhagic stroke, ototoxicity |
| what is hemorrhagic stroke | bleeding in the brain |
| What is ototoxicity | ear infection |
| What is the 1st sign of ototoxicity | ringing in the ears |
| To decrease risk of GI bleeding advise patients taking aspirin (Anti-platelet) to | use enteric coated aspirin and take with food |
| If GI symptoms are sever patient may need to take | a protron pump inhibitor with aspirin |
| When should Aspirin (anti-platelet) not be taken | 3rd trimester of pregnancy, bleeding disorders, thrombocytopenia |
| Caution should be used when giving anti-platelets to patients with | peptic ulcer disease,renal disorders, hepatic disorders |
| What medications when taken with aspirin increase the risk for bleeding | heparin, warfarin, NSAID'S & some herbs |
| Which herbal products when taken with aspirin increase risk of bleeding | don quai, fever few, garlic, ginkgo |
| Taking a low dose aspirin (81mg)may prevent | strokes, acute MI, and reinfarction |
| How long after stopping anti-platelet therapy will the drug remain in the system | 7 days |