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tricyclic antidepressants

TCAs: prototype Amytriptyline others: imipramine, doxepin, nortriptyline, amoxapine, trimipramine, desipramine, clomipramine TX: depression, depressive episodes of bipolar disorders other uses: neyropathic pain, fibromyalgia, anxiety disorders, OCD, insomnia, ADHD
TCAs complications Orthostatic hypotention, anticholiergic effects, sedation, toxicity, decreased seizure threshold, excessive sweating
anticholinergic effects dry mouth, blurred vision, photophobia, urinary hesitancy or retention, constipation, tachycardia.
TCAs contraindications/precautions don't give to clients w/seizures disorder or w/ myocardial infarction. cautious w/elderly or clients w/CAD, diabetes, liver, kidney, or resp. disorders, urinary retention or obstruction, angle-closure glaucoma, benighn hyperplasia, hyperthyroidism. preg
TCAs interactions avoid concurrent use w/MAOIs, St. John's Wort (can lead to serotonin syndrome), antihistamines, other anticholinergic agents, epinephrine dopamine, ephedrine amphetamine, alcohol, opioids, benzodiazepines
Created by: gdimanche