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Side effects include muscular rigidity and cramping, a stiff or thick tongue with difficulty swallowing. usually occurs in the 1st week of treatment, in pt under 40yo, males, drugs involved Haloperidol & Thiothixene Dystonia
twisted head and neck torticollis
tightness in the entire body with the head back and an arched neck opisthotonus
eyes rolled back in a locked position oculogyric crisis
loss of coordination of muscles especially those of the extremities ataxia
what medications are used to treat Acute Dystonia IM benztropine mesylate or IM/IV diphenhydramine
intense need to move about akathisia
a potentially fatal idiosyncratic reaction to an antipsychotic drug. often occurs in the first 2 weeks of treatment or after a increase in dosage. Neuroleptic malignant syndrome
S/S rigidity, high fever, autonomic instability such as unstable BP, diaphoresis, pallor, delirium, and elevated levels of enzymes NMS neuroleptic malignant syndrome
TX immediate discontinuance of all antipsychotic medication and the institution of supportive medical care to treat dehydration and hyperthermia NMS neuroleptic malignant syndrome
S/S involuntary movement of the tongue, facial and neck muscles, upper/lower extremities. tongue thrusting & protruding, lip smacking, blinking, grimacing after it develops it is irreversible. Tx includes Atypical antipsychotic drugs Tardive dyskinesia
S/S stiff stooped posture, mask-like-facies, decreased arm swing, a shuffling, festinating gait (small steps), cogwheel rigidity (ratchet like movements of joints), drooling, tremor, bradycardia, pill rolling pseudoparkinsonism
ziprasidone is contraindicated in pt with a known HX of QT prolongation, recent MI, or uncompensated heart failure. it should not be used with other QT-prolonging drugs FYI
acute dystonia, pseudoparkinism, akathisia extrapyramidal symptoms
clients taking anticholinergic agents for EPS may have problems with anticholinergic side effects. Side effects usually decrease within 3-4 weeks but don't entirely remit FYI
this drug may cause agranulocytosis, which may not show up for 24 weeks after TX is started. It also causes pt to have a baseline WBC count & differential before initiation of TX and Q weekly for 6 months and 4 weeks after discontinuation Clozapine (Atypical antipsychotic)
Created by: jackie_ridley