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What is the trade name for calcium? Apo-cal 500
What is the generic name for Apo-cal 500 Calcium
What is the classification for Calcium (Apo-cal 500) Antacid, Calcium supplement
What is the mechanism of action for Calcium? Neutralizes gastric acidity
What is the pharmacokinetics for Calcium? 1/3 dose absorbed by small intestine, excreted by urine & fees, crosses placenta, must have adequate vitamin D for absorption
What are the indications/uses for Calcium? Antacid, calcium supplement; unlabeled uses: duodenal ulcer, PMS, stress gastritis
What are some side effects of Calcium? GI-> constipation, anorexia, nausea, vomiting, diarrhea, rebound hyperacidity GU-> calculi, hypercalciuria
What are some contraindications of Calcium? hypersensitivity, hypercalcemia precautions; pregnancy, breastfeeding, geriatric pt's, fluid restriction, GI obstruction, dehydration, renal disease, hyperparathyroidism, bone tumours
What is the dosage/route of administration for Calcium? 500mg (1 tablet) PO TID (3x a day)
What are the nursing implications for Calcium? assessing for constipation, hypercalcemia, headache, nausea, vomiting, confusion, hypocalcemia, parasthesia, twitching, colic, dysrhythmias, Chvostek's sign, Trousseau's sign, evaluating for absence of pain, decreased activity
What is the generic name for Cyanocobalamin? Vitamin B-12
What is the trade name for Vitamin B-12? Cyanocobalamin
What is the classification of Vitamin B-12? Vitamin B-12, water soluble vitamin
What is the mechanism of action for Vitamin B-12? Needed for adequate nerve functioning, protein and carb metabolism, normal growth, RBC development, cell reproduction
What is the pharmacokinetics of Vitamin B-12? Gastric intrinsic factor must be present for absorption to occur; stored in liver, kidneys, stomach; 50-90% excreted in urine, crosses placenta, excreted in breast milk
What are the indications/uses for Vitamin B-12? Vitamine B-12 deficiency, pernicuous anemia, vit b-12 malabsorption syndrome, schilling test, increased requirements w pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, renal/hepatic disease, nutritional supplementation
What are the side effects of Vitamin B-12? CNS-> flushing, optic nerve atrophy CV-> CHF, peripheral vascular thrombosis, pulmonary edema GI-> diarrhea INTEG-> itching, rash, pain at inj site META-> hypokalemia SYST-> anaphylactic shock
What are the contraindications of Vitamin B-12? Hypersensitivity to this product, cobalt, benzyl alcohol, optic nerve atrophy; precautions: pregnancy, breast feeding, children, renal/hepatic disease, folic acid-iron deficiency, anemia, infection
What is the dosage/route of administration for Vitamin B-12? 1,000 mg (1 tablet) PO daily
What are the nursing implications for Vitamin-B12? Assess vit b-12 deficiency (red, beefy tongue) psychosis,pallor neuropathy,diarrhea,constipation, pulmonary edema,worsening or CHF in cardiac pt's,evaluate decreased anorexia,dyspnea on exertion,palpitations,paresthesias,psychosis, visual disturbances
Want is the generic name for Dabigatran? Pradaxa
What is the trade name for Pradaxa? Dabigatran
What is the classification of Pradaxa? Anticoagulant, thrombin inhibitor
What is the mechanism of action for Pradaxa? direct thrombin inhibitor that inhibits both free and clot-bound thrombin, prevents thrombin-induced platelet aggregation and thrombus formation by preventing conversion of fibrinogen to fibrin
What is the pharmacokinetics of Pradaxa? Protein binding 35%, half life 12-17 hours (extended in renal disease), peak 1 hour, high-fat meal delays peak
What are the indications/uses of Pradaxa? Stroke/systemic embolism prophylaxis w nonvalvular atrial fibrillation, DVT, pulmonary embolism in hip placement
What are the side effects of Pradaxa? intrancranial bleeding, myocardial infarction, abdominal pain, dyspepsia, peptic ulcer, esophagitis, GERD, gastritis, GI bleeding, bleeding anywhere, hemorrhagic erosive gastritis, rash, pruritus, anaphylaxis
What are the contraindications of Pradaxa? hypersensitivity, bleeding, prothetic heart valves; precautions- pregnancy, labor, obstetric delivery, breastfeeding, children, geriatric pt's, abrupt discontinuation, anticoagulant therapy, renal disease, surgery
What is the dosage/route of administration for Pradaxa? 150mg (1capsule) PO q12h
What are the nursing implications for Pradaxa? assess blood in urine or emesis, dark tarry stools, lower back pain, caution w catheter, monitor VS, bleeding, swelling, pain, redness, difficulty breathing, chest pain, tachypnea, coughing blood, cyanosis, itching/tingling, swelling, skin discoloration
What is the generic name for Diltiazem? Cardizem
What is the trade name for Cardizem? Diltiazem
What is the classification for Cardizem? calcium channel blocker, anti arrhythmic class IV, antihypertensive, benzothiazepine
What is the mechanism of action for Cardizem? Inhibits calcium ion influx across cell membrane during cardiac depolarization; produces relaxation of coronary vascular smooth muscle, dilates coronary arteries, slows SA/AV node conduction times, dilates peripheral arteries
What is the pharmacokinetics of Cardizem? Onset 30-60 minutes; peak 2-3 hours, immediate release, 10-14 hour extended release, 11-18 hr sustained release; half life 3.5-9hour, metabolized by liver, excreted in urine (96% as metabolites)
What are the indications/uses of Cardizem? Motion sickness, nausea, vomiting, vertigo; Unlabeled Uses: hyperemesis gravidarum, Meniere's syndrome
What are the side effects of Cardizem? headache, fatigue, drowsiness, dizziness, depression, weakness, insomnia, tremor, paresthesia, dyrhythmia, edema, CHS, bradychardia, hypotension, palpitations, heart block, nausea, vomiting, diarrhea, gastric upset, constipation, increased LFTs,polyuria..
What are the contraindications of Cardizem? sick sinus syndrome, AV heart block, hypotension <90 systolic, acute MI, pulmonary congestion, cariogenic shock precautions: pregnancy, breast feeding, children, geriatric puts, CHF, aortic stenosis, bradycardia, GERD, hepatic disease, hiatal hernia...
What is the dosage/route of administration of Cardizem? 360mg (2 capsules) PO daily
What are the nursing implications for Cardizem? Assess CHF(Dyspnea, weight gain, deem, jugular venous distention, ratles), monitor I&O ratios daily, weight; gain, dysrhythmias(cardiac stats,BP,pulse, rest, ECG and intervals), evaluate therapeutic response,decreased anginal pain, decreased BP
What is the generic name for Docusate Sodium (OTC) Colace
What is the trade name for Colace? Docusate Sodium (OTC)
What is the classification for Colace? laxative, emollient; stool softener, anionic surfactant
What is the mechanism of action for Colace? increases water, fat penetration in intestine, allows for easier passage of stool
What is the pharmacokinetics for Colace? onset 12-72 hours
What are the indications/uses for Colace? prevention of dry, hard stools
What are the side effects of Colace? bitter taste, throat irritation, nausea, anorexia, cramps, diarrhea, rash
What are the contraindications of Colace? hypersensitivity, obstruction, fecal impaction, nausea/vomiting precautions: pregnancy, breastfeeding
What is the dosage/route of administration for Colace? 100mg (1 capsule) PO BID - AM & HS
What are the nursing implications for Colace? assess if fluids, bulk or exercise is missing from lifestyle, constipating products, cramping, rectal bleeding, nausea, vomiting; if these occur should be discontinued, evaluate therapeutic response: decrease in constipation
What is the trade name for Femara? Letrozole (Rx)
What is the generic name for Letrozole (Rx) Femara
What is the classification of Femara? antineoplastic, non-steroidal aromatase inhibitor
What is the mechanism of action for Femara? Binds to the heme group of aromatase; inhibits conversion of androgens to estrogens to reduce plasma estrogen levels
What is the pharmacokinetics for Femara? Metabolized in liver, excreted in urine, peak 2 days, terminal half-life 48 hours, steady state 2-6 weeks
What are in the indications/uses for Femara? early, advanced, or metastatic breast cancer in postmenopausal women who are hormone receptor positive; unlabeled uses: infertility, idiopathic short stature, constitutional delayed puberty
What are the side effects of Femara? headache, lethargy, sombolence, dizziness, depression, anxiety, angina, MI, CVA, thromboembolic events, hypertension, peripheral edema, nausea, vomiting, anorexia, constipation, heartburn, diarhea, rash, pruritus, hot flashes, dyspnea, cough, myalgia...
What are the contraindications of Femara? pregnancy, premenopausal females, hypersensitivity; precautions: respiratory/hepatic disease, osteoporosis
What is the dosage/route of administration for Femara? 2.5mg (1 tablet) PO daily (don't crush, chew, open unless approved)
What is the nursing implications for Femara? Assess hepatic studies before, during therapy (bilirubin, AST, ALT, LDH) as needed or monthly, evaluate therapeutic response (decrease in size of tumour)
What is the generic name for Levothyroxine? Eltroxin
What is the trade name for Eltroxin? Levothyroxine
What is the classification for Eltroxin? Thyroid hormone, Levoisomer of thyroxine
What is the mechanism of action for Eltroxin? Increases metabolic rate, controls protein synthesis, increases cardiac output, renal blood flow, O2 consumption, body temp, blood volume, growth, development at cellular level via action on thyroid hormone receptors
What is the pharmacokinetics for Eltroxin? half-life euthyroid 6-7 days, hypothyroid 9-10 days, hyperthyroid 3-4 days, distributed throughout body tissues; PO: onset 24 hours
What are the indications/uses for Eltroxin? Hypothyroidism, myxedema coma, thyroid hormone replacement, thyrotoxicosis, congential hypothyroidism, some types of thyroid cancer, pituitary TSH suppression
What are the side effects of Eltroxin? anxiety, insomnia, tremors, headache, tachycardia, palpitations, gain, hypertension, dysrhythmias, nausea, diarrhea, increase/decreased appetite, cramps, weight loss, sweating, fever, alopecia, menstrual irregularities, decreased bone mineral density....
What are the contraindications for Eltroxin? adrenal insufficiency, recent MI, thyrotoxicosis, hypersensitivity to beef, alcohol intolerance (in only)
What is the dosage/route of administration for Eltroxin? 75mg (1tablet) PO daily @ 0700 (take on empty stomach)
What are the nursing implications for Eltroxin?
What is the trade name for Actonel? Risedronate (Rx)
What is the generic name for Risedronate (Rx)? Actonel
What is the classification for Actonel? Bone resorption inhibitor, biphosphonate
What is the mechanism of action of Actonel? Inhibits bone resorption, absorbs calcium phosphate crystal in bone, and may directly block dissolution of hydroxyapatite crystals of bone
What is the pharmacokinetics for Actonel? Rapidly cleared from circulation, taken up mainly by bones (50%), eliminated primarily through kidneys, absorption, decreased by food, terminal half-life 230 hours
What are the indications/uses for Actonel? Paget's disease prevention, treatment of osteoporosis in postmenopausal women; glucocorticoid-induced osteoporosis, osteoporosis in en; unlabeled uses osteolytic metastases
What are the side effects of Acontel? Dizziness, headache, depression, asthenia, insomnia, weakness, chest pain, hypertension, atrial fibrillation, abdominal pain, diarrhea, nausea, constipation, esophagitis, rash, UTI, pharyngitis, hypocalcemia, increase PTH, osteonecrosis of jaw..
What are the contraindications for Actonel? Hypersensitivity to biphosphonates, inability to stand or sit upright for >30 min, esophageal stricture, achalasia, hypocalcemia precautions: pregnancy,children, renal disease, active upper GI disorders, dental disease, Vit D deficiency, asthma ...
What is the dosage/route of administration for Actonel?
What are the nursing implications for Actonel? Assess for Paget's disease (headache,bone pain,increased head circumference), osteoporosis, hypocalcemia, serious skin reactions, dental health, evaluate therapeutic response: increased bone mass, absence of fractures
What is the generic name for Acetaminophen? Tylenol
What is the trade name for Tylenol? Acetaminophen
What is the classification for Tylenol? Non-opiod analgesic, antipyretic, nonsalicylate, paraaminophenol derivative
What is the mechanism of action for Tylenol? May block pain impulses peripherally that occur in response to inhibition of prostaglandin synthesis; does not possess inflammatory properties; antipyretic action results from inhibition of prostaglandins in the CNS (hypothalamic heat-regulating centre)
What is the pharmacokinetics of Tylenol? 85-90% metabolized by liver, excreted by kidneys, metabolites may be toxic if overdose occurs; widely distributed; crosses placenta in low concentrations; excreted in breast milk; half life 1-4hours
What are the indications/uses for Tylenol? Mild to moderate pain or fever, arthralgia, dental pain, dysmenorrhea, headache, myalgia, osteoarthritis; unlabeled used -> migraine
What are the side effects of Tylenol? Nausea, vomiting, abdominal pain, hepatoxicity, hepatic seizures (overdose), GI bleeding, renal failure (high, prolonged doses), leukopenia, neutropenia, hemolytic anemia, rash, inj site pain, Stevens-Johnson syndrome, cyanosis, anemia, jaundice ...
What are the contraindications for Tylenol? Hypersensitivity to this product or phenacetin; precautions: pregnancy, breastfeeding, geriatric pt's, anemia, renal/hepatic disease, chronic alcoholism
What is the dosage/route of administration for Tylenol? 325mg caplet (1-2 tabs) PO q4h PRN (for temp > 37.5 or pain< recommended max 4gm/day, 2gm/day of on Warfarin)
What are the nursing implications for Tylenol? Asses hepatic studies (AST, ALT,bilirubin, creatinine before therapy if long-term therapy is anticipated; may cause hepatic toxicity at doses >4g a day w chronic use, renal studies (BUN,urine creatinine,albumin,occult blood), blood studies..
What is the generic name for Bisacodyl? Dulcolax
What is the trade name fro Dulcolax? Bisacodyl
What is the classification of Dulcolax? Laxative, stimulant, diphenylmethane
What is the mechanism of action for Dulcolax? Acts directly on intestine by increasing motor activity; thought to irritate colonic intramural plexus
What is the pharmacokinetics for Dulcolax? Small amounts absorbed/metabolized by liver, excreted in urine, bile, faces, breast milk; PO (onset 6-10hrs), RECT (onset 15-60min)
What are the indications/uses for Dulcolax? short-term treatment of constipation, bowel or rectal preparation for surgery, examination
What are the side effects of Dulcolax? muscle weakness, nausea, vomiting, anorexia, cramps, diarrhea, rectal burning(Supps), protein-losing enteropathy, alkalosis, hypokalemia, tetany; electrolyte fluid imbalances
What are the contraindications for Dulcolax? hypersensitivity, abdominal pain, nausea, vomiting, appendicitis, acute surgical abdomen, ulcerated hemorrhoids, acute hepatitis, fecal impaction, intestinal/biliary tract obstruction; precautions: pregnancy, breast feeding, rectal fissures, severe CVdise
What is the dosage/route of administration for Dulcolax? 10mg (1supp) PR daily PRN
What are the nursing implications for Dulcolax? Assess blood, urine electrolytes if product is used often by pt, I&O ratio is identify fluid loss, cause of constipation, GI symptoms. Evaluate therapeutic response (decrease in constipation)
What is the generic name for Lactulose? Lactulose, Lactulax, Acilac
What is the trade name for Lactulose? Lactulose
What is the classification for Lactulose? laxative, ammonia detoxicant (hyperosmotic), lactose synthetic derivative
What is the mechanism of action for Lactulose? Prevents absorption of ammonia in colon by acidifying stool; increases water, softens stool
What is the pharmacokinetics for Lactulose? Metabolized in colon, onset 1-2 days, peak unknown, duration unknown
What are the indications/uses for Lactulose? Chronic constipation, portal systemic encephalopathy in pt's w hepatic disease
What are the side effects for Lactulose? nausea, vomiting, anorexia, abdominal cramps, diarrhea, flatulence, distention, belching, hypernatremia
What are the contraindications for Lactulose? hypersensitivity, low-galactose diet; precautions: pregnancy, breastfeeding, geriatric pt, debilitated pt, diabetes mellitus
What is the dosage/route of administration for Lactulose? 30ml PO daily PRN
What are the nursing implications for Lactulose? Assess stool, cause of constipation, blood, urine electrolytes, I&O ratio to identify fluid loss, replace any loss, cramping/rectal bleed/nausea,vomiting should be dscontd, evaluate therapeutic response (decrease constipation, decreased bloodammonialeve .
Created by: breannekwasny