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FINAL - Viruses

Final cumulative virus review

Viral FamilyEnveloped?DNA/RNA structure?Key virusesAssociated diseases
Parvovirus No ssDNA (linear) THE SMALLEST DNA VIRUS B19 virus aplastic crisis in sickle cell, erythema infectiosum (5th disease) - slap cheek - may be referred to as erythrovirus in this case), hydrops fetalis
Papovavirus No DS - Circular HPV, JC Virus HPV - Warts, CIN, Cervical cancer.JC - Progressive multifocal leukoencephalopathy (PML) in HIV pt
Poxvirus Yes dsDNA, Linear (largest DNA virus) Poxvirus Smallpox (eradicated), vaccinia - cowpox (milkmaid blisters), Molluscum contagiosium
Picornaviruses No (+)ssRNA with icosahedral capsule Poliovirus, Echovirus, Rhinovirus, Coxsackie, HAV Poliovirus (salk vaccine injection(oral sabin is no longer used). Echovirus - Asepetic meningitis, Rhinovirus - common cold, Coxsackie virus - Asepetic meningitis, herpangina (febrile pharyngitis), HAND FOOT AND MOUTH DISEASE, and myocarditis. HAV - Hep A
Calciviruses No Linear (+)ssRNA Icosahedral capsule HEV and Norwalk virus HEV: Hep E; Norwalk virus: viral gastroenteritis
Reoviruses No dsRNA, Linear, Segmented. Icosahedral Rotavirus, reovirus Rotavirus: - #1 viral dirrhea (sometimes fatal) in children <2 and in the elderly.Reovirus: Colorado tick fever
Flavivirus Yes (+)ssRNA, Linear, Icosahedral HCV, flavivirus HCV - Hep C. Flavivirus: Yellow fever, dengue, St. Louis encephalitis, West nile.
Togavirus Yes (+)ssRNA, Linear, icosahedral Togavirus Rubella, Eastern equine encephalitis, western equine encephalitis
Retroviruses Yes (+)ssRNA, Linear, Icosahedral HIV, HTLV HIV - AIDS, HTLV - T-cell leukemia. These viruses contain reverse transcriptase
Coronavirus Yes (+)ssRNA, Linear, HELICAL Corona virus Common cold and SARS
Orthomyxovirus Yes (-)ssRNA, Linar segmented (compare to paramyxo which is NOT segmented), helical capsule Influenza virus Influenza A and B
Paramyxovirus Yes (-) ssRNA, Linear, NON-SEGMENTED (compare to ortho which is segmented), helical Parainfluenza, RSV PaRaMyxovirus:Parainfluenza - croup, RSV - bronchiolitis in babies, (rx=ribavirin), measles, mumps.
Rhabdoviruses Yes (-)ssRNA, Linear, helical, Rabies virus Rabies
Filovirus Yes (-)ssRNA, Linear, Helical Filovirus Ebola/marburg hemorrhagic fever
Arenavirus Yes (-)ssRNA, CIRCULAR, Helical LCV Lymphocytic choriomeningitis and mice-borne viral meningitis
Bunyavirus Yes (-)ssRNA, CIRCULAR, helical Bunyavirus, Hantavirus California enchephalitis, sand fly / rift valley fever, crimmean-congo hemorrhagic fever. HANTAVIRUS - Hemorrhagic fever, pneumonia
Deltavirus Yes (-)ssRNA, Circular, helical HDV Hep D
Hepadnavirus Yes DS - Partial circular HBV : Acute / chronic hepatitis. Vaccine available. NOT A RETROVIRUS BUT CONTAINS REVERSE XCRIPTASE
Herpesvirus Yes DS - Linear HSV-1, HSV-2, VZV, EBV, CMV HSV-1 - Oral lesions, keratoconjunctivitis.HSV-2 Genital lesionsVZV - Chicken pox, zoster, shinglesEBV - Mono, burkits lymphomaCMV - Immunosupressed pt, xplant recip. Congenital defects
Adenovirus No DS - Linear Adenovirus Febrile pharyngitis (sore throat), pneumonia, Conjunctivitis (pink eye)
Created by: Semester4