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membranes
week 6
| Question | Answer |
|---|---|
| Three forms of active transport | ATP driven, coupled, light |
| Describe ATP driven transport | Hydrolysis of ATP to ADP releases large amounts of energy which can be harnessed to drive thermodynamically unfavourable reactions |
| Describe coupled transport | co-transported with a molecule that is moving down concentration gradient-net effect is favourable |
| The two main types of membrane protein transporters | Carriers and channels |
| Describe carrier transport proteins | Substrate molecule binds on one side of the membrane, the carrier undergoes conformational change and releases the substrate on the other side of the membrane |
| Describe channel transport proteins | Form a hydrophilic pore within the membrane which can open or close, allowing passage of molecules through pore. Discriminates on basis of size and e- charge |
| What is a carbohydrate layer? | A layer of sugar residues, including polysaccharide portions of proteoglycans and oligosaccharides attached to protein or lipid molecules, on the noncytosolic side of the membrane |
| Give examples of amphiphatic molecules | phosphatidylcholine, phospholipids, sterol, glycolipids |
| Three ways in which proteins are imported into organelles | Transport through nuclear pores, transport across membranes, transport by vesicles |
| Describe the constitutive exocytosis pathway | Steady stream of vesicles that bud from the trans Golgi network and fuse with plasma membrane; supplying newly made lipids and proteins to membrane |
| Describe the role of chaperones and where they are found | Class of proteins that recognise misfolding of proteins, which are directed to the cytoplasm for degradation. Chaperones are found in the ER. |