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Respiratory

Burkholderia Species

QuestionAnswer
Why is Burkholderia cepacia actively sought out in patients with CF? Once this organism is in their system the patients life span is significantly shortened and severity of disease is increased, they have to isolated from the other CF community, and they are taken off the lung transplant list.
What does Burkholderia cepacia colonies look like? Non-wrinkled, yellow pigmented colonies
What agars should be used to best recover Burkholdria cepacia? and in what enviromental conditions? Pseudomonas cepacia (PC), Oxidative-fermentative Base, polymixin B, Bacitracin, Lactose (OFPBL), Burkholderia cepacia selective agar (BCSA) Grows best at 30*C (slow grower) 4 or more days
What disease does burkholderia pseudomallei cause? and what do its colonies look like? Melioidosis or a glanders-like disease, an aggressive granulomatous pulmonary disease A wrinkled colony with earthy odor, lactose + to differentiate from P. stutzeri
what other disease can Burkholderia cepacia cause? and in what population does this mostly effect? Foot rot- especially in the diabetic population
What disease does Burkholderia mallei cause? Is this organism cause for concern in humans? Glanders disease- a disease of horses, mules, and donkeys, not a problem in humans unless close contact with infected animal. Human infections rare. Considered a potential bioterrorist agent
What Burkholderia organism can be mistaken for Burkholderia cepacia? and what are its colonies characteristics? Burkholderia gladioli- plant pathogen mistaken for cepacia. Produces a yellow pigment and more susceptible to antibiotics then cepacia
Created by: Cgover7