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MHC16 Antipsych Dose

Typical maintenance dosages of antipsychotics for MHC16 class

Drug NameStandard Dose
Chlorpromazine / Thorazine (t) 75–300 mg daily (but up to 1 g daily may be required in psychoses) IM (for relief of acute symptoms), 25–50 mg every 6–8 hours
Fluphenazine / Prolaxin, Modecate (t) 1-5 mg PO/IM divided q6-8hr; not to exceed 40 mg/day IM 12.5–100 mg repeated at intervals of 14–35 days, adjusted according to response
Haloperidol / Haldol (t) (Schizophrenia, psychoses, mania and hypomania, organic brain damage) 1–3 mg three times daily adjusted according to response (max. 20 mg daily in divided doses)
Clozapine / Clozaril (a) (Schizophrenia) usual dose 200–450 mg daily (max. 900 mg daily)
Olanzapine / Zyprexal (a) Schizophrenia, combination therapy for mania, preventing recurrence in bipolar disorder; usual range of 5–20 mg daily. Monotherapy for mania; usual range of 5–20 mg daily. IM; initially 5–10 mg single dose followed by 5–10 mg after 2 hours if necessary
Quetiapine / Seroquel (a) Schizophrenia; , usual range 300–450 mg daily in 2 divided doses; max. 750 mg daily. Bipolar disorder; usual range 300–800 mg in 2 divided doses (adjust to lowest effective dose)
Risperidone / Risperdal (a) Psychosis: usual dose range 4–6 mg daily; doses above 10 mg daily only if benefit considered to outweigh risk (max. 16 mg daily) Mania: usual dose range 1–6 mg daily
Created by: JMHC16