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Drug profiles

Bumex, thiamine morphine, phenergan, valium

QuestionAnswer
BUMETANIDE GENERIC NAME BUMETANIDE
BUMETANIDE BRAND NAME Bumex
BUMETANIDE CLASS Loop diuretic
BUMETANIDE MECHANISM OF ACTION Inhibits electrolyte reabsorption.
BUMETANIDE INDICATIONS Pulmonary edema, CHF
BUMETANIDE CONTRAINDICATIONS Hypersensitivity, Anuria, Electrolyte deficiencies, Hepatic coma.
BUMETANIDE ADVERSE REACTIONS Dizziness , headache, Hypotension, ECG changes, N/V, ringing in the ears.
BUMETANIDE INCOMPATABILITIES/DRUG INTERACTIONS Lithium toxicity may be potentiated by electrolyte depletion. Potentiates effects of various antihypertensive drugs
BUMETANIDE DOSE/ROUTE Adult 0.5 to 1.0 mg IV slowly over 1 to 2 minutes, or IM
BUMETANIDE ONSET OF ACTION IV Immediate
BUMETANIDE PEAK EFFECTS IV 15-30 minutes
BUMETANIDE DURATION OF ACTION 2-4 hours
BUMETANIDE AZ DRUG BOX SUPPLY RANGE 4mg
Promethazine GENERIC NAME Promethazine
Promethazine BRAND NAME Phenergan,
Promethazine CLASS Antiemetics, antihistamine, sedative/hypnotics
Promethazine MECHANISM OF ACTION Decreases N/V by antagonizing H1 receptors
Promethazine INDICATIONS Treatment and prevention of N/V
Promethazine CONTRAINDICATIONS Narrow-angle glaucoma, children less then 2yr.
Promethazine ADVERSE REACTIONS Confusion, disorientation, sedation, dizziness, nervousness. Blurred vision, diplopia.
Promethazine INCOMPATABILITIES/DRUG INTERACTIONS Potentiates other CNS depressants, Potentiates other drugs possessing anticholinergic properties.
Promethazine DOSE/ROUTE Adult antihistamine IV 25mg, may repeat in 2hr.
Promethazine DOSE/ROUTE Adult antiemetic IV 25mg Q4hr PRN.
Promethazine DOSE/ROUTE Peds antihistamine IV Not recommended
Promethazine DOSE/ROUTE Peds antiemetic IV 0.25-0.5 mg/kg q 4-6 hours
Promethazine ONSET OF ACTION IV 5 minutes
Promethazine PEAK EFFECTS Unknown
Promethazine DURATION OF ACTION 12 hours
Promethazine AZ DRUG BOX SUPPLY RANGE Not carried
Thiamine GENERIC NAME None
Thiamine BRAND NAME Thiamine
Thiamine CLASS Vitamin B1
Thiamine MECHANISM OF ACTION Combines with ATP to form thiamine pyrophosphate coenzyme, a necessary component for carbohydrate metabolism. Thiamine INDICATIONS
Thiamine CONTRAINDICATIONS None
Thiamine ADVERSE REACTIONS Hypotension from to rapid of an injection or to high of a dose, diaphoresis, N/V.
Thiamine INCOMPATABILITIES/DRUG INTERACTIONS Give thiamine before glucose under all circumstances.
Thiamine DOSE/ROUTE Adult 100mg slow IV, or IM
Thiamine DOSE/ROUTE Pediatric 25mg slow IV, or IM
Thiamine ONSET OF ACTION Rapid
Thiamine PEAK EFFECTS Variable
Thiamine DURATION OF ACTION Variable
Thiamine AZ DRUG BOX SUPPLY RANGE 100mg
Diazepam GENERIC NAME Diazepam
Diazepam BRAND NAME Valium
Diazepam CLASS Benzodiazepine, sedative hypnotic, anticonvulsant
Diazepam MECHANISM OF ACTION Potentiates effects of inhibitory neurotransmitters. Raises seizure threshold. Induces amnesia and sedation.
Diazepam INDICATIONS anxiety, alcohol withdrawal, muscle relaxant, seizure activity, agitation. Analgesia for medical procedures.
Diazepam CONTRAINDICATIONS glaucoma, coma, shock, substance abuse, head injury
Diazepam ADVERSE REACTIONS Respiratory depression, hypotension. Drowsiness, nausea, confusion,
Diazepam INCOMPATABILITIES/DRUG INTERACTIONS Incompatible with most drugs, fluids.
Diazepam DOSE/ROUTE Adult, seizure activity 5-10mg IV q 10-15 minutes prn. Max dose 30mg.
Diazepam DOSE/ROUTE Adult, cardioversion sedation 5-15mg IV over 5-10 minutes prior to cardioversion.
Diazepam DOSE/ROUTE Pediatric, seizure activity 0.2-0.5mg slowly q 2-5 minutes up to 5mg. max dose 10mg/kg.
Diazepam DOSE/ROUTE Pediatric, rectally 0.5 mg/kg via 2’’ rectal catheter and flush with 2-3ml of air after administration.
Diazepam ONSET OF ACTION 5 minutes
Diazepam PEAK EFFECTS minutes
Diazepam DURATION OF ACTION 50 minutes
Diazepam AZ DRUG BOX SUPPLY RANGE 20mg. Rectal 20mg (optional)
Morphine GENERIC NAME Morphine Sulfate
Morphine BRAND NAME Astramorph/pf
Morphine CLASS Opioid analgesic (schedule II narcotic)
Morphine MECHANISM OF ACTION Alleviates pain through CNS action, Suppresses fear and anxiety centers in brain
Morphine INDICATIONS CHF, pulmonary edema, chest pain associated with acute MI, analgesia for pain
Morphine CONTRAINDICATIONS depressed respiratory drive, hypotension, undiagnosed abdominal pain, decreased LOC, Shock,
Morphine ADVERSE REACTIONS Respiratory depression, hypotension, decreased LOC, N/V, Bradycardia, tachycardia, syncope
Morphine INCOMPATABILITIES/DRUG INTERACTIONS CNS depressant may potentiate effects of morphine. MAOIs may cause paradoxical excitation.
Morphine DOSE/ROUTE Adult Initial dose 2-4 mg IV.
Morphine DOSE/ROUTE Repeat dose 2-8 mg at 5-15 minute intervals.
Morphine DOSE/ROUTE Pediatric .1-.2 mg/kg per dose via IV. IO. IM, or SC; Maximum dose of 5mg.
Morphine ONSET OF ACTION Immediate
Morphine PEAK EFFECTS 20 minutes
Morphine DURATION OF ACTION 7 hours
Morphine AZ DRUG BOX SUPPLY RANGE 20mg
Created by: klindley