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Drug profiles
Bumex, thiamine morphine, phenergan, valium
| Question | Answer |
|---|---|
| BUMETANIDE GENERIC NAME | BUMETANIDE |
| BUMETANIDE BRAND NAME | Bumex |
| BUMETANIDE CLASS | Loop diuretic |
| BUMETANIDE MECHANISM OF ACTION | Inhibits electrolyte reabsorption. |
| BUMETANIDE INDICATIONS | Pulmonary edema, CHF |
| BUMETANIDE CONTRAINDICATIONS | Hypersensitivity, Anuria, Electrolyte deficiencies, Hepatic coma. |
| BUMETANIDE ADVERSE REACTIONS | Dizziness , headache, Hypotension, ECG changes, N/V, ringing in the ears. |
| BUMETANIDE INCOMPATABILITIES/DRUG INTERACTIONS | Lithium toxicity may be potentiated by electrolyte depletion. Potentiates effects of various antihypertensive drugs |
| BUMETANIDE DOSE/ROUTE Adult | 0.5 to 1.0 mg IV slowly over 1 to 2 minutes, or IM |
| BUMETANIDE ONSET OF ACTION | IV Immediate |
| BUMETANIDE PEAK EFFECTS | IV 15-30 minutes |
| BUMETANIDE DURATION OF ACTION | 2-4 hours |
| BUMETANIDE AZ DRUG BOX SUPPLY RANGE | 4mg |
| Promethazine GENERIC NAME | Promethazine |
| Promethazine BRAND NAME | Phenergan, |
| Promethazine CLASS | Antiemetics, antihistamine, sedative/hypnotics |
| Promethazine MECHANISM OF ACTION | Decreases N/V by antagonizing H1 receptors |
| Promethazine INDICATIONS | Treatment and prevention of N/V |
| Promethazine CONTRAINDICATIONS | Narrow-angle glaucoma, children less then 2yr. |
| Promethazine ADVERSE REACTIONS | Confusion, disorientation, sedation, dizziness, nervousness. Blurred vision, diplopia. |
| Promethazine INCOMPATABILITIES/DRUG INTERACTIONS | Potentiates other CNS depressants, Potentiates other drugs possessing anticholinergic properties. |
| Promethazine DOSE/ROUTE Adult antihistamine IV | 25mg, may repeat in 2hr. |
| Promethazine DOSE/ROUTE Adult antiemetic IV | 25mg Q4hr PRN. |
| Promethazine DOSE/ROUTE Peds antihistamine IV | Not recommended |
| Promethazine DOSE/ROUTE Peds antiemetic IV | 0.25-0.5 mg/kg q 4-6 hours |
| Promethazine ONSET OF ACTION | IV 5 minutes |
| Promethazine PEAK EFFECTS | Unknown |
| Promethazine DURATION OF ACTION | 12 hours |
| Promethazine AZ DRUG BOX SUPPLY RANGE | Not carried |
| Thiamine GENERIC NAME | None |
| Thiamine BRAND NAME | Thiamine |
| Thiamine CLASS | Vitamin B1 |
| Thiamine MECHANISM OF ACTION | Combines with ATP to form thiamine pyrophosphate coenzyme, a necessary component for carbohydrate metabolism. Thiamine INDICATIONS |
| Thiamine CONTRAINDICATIONS | None |
| Thiamine ADVERSE REACTIONS | Hypotension from to rapid of an injection or to high of a dose, diaphoresis, N/V. |
| Thiamine INCOMPATABILITIES/DRUG INTERACTIONS | Give thiamine before glucose under all circumstances. |
| Thiamine DOSE/ROUTE Adult | 100mg slow IV, or IM |
| Thiamine DOSE/ROUTE Pediatric | 25mg slow IV, or IM |
| Thiamine ONSET OF ACTION | Rapid |
| Thiamine PEAK EFFECTS | Variable |
| Thiamine DURATION OF ACTION | Variable |
| Thiamine AZ DRUG BOX SUPPLY RANGE | 100mg |
| Diazepam GENERIC NAME | Diazepam |
| Diazepam BRAND NAME | Valium |
| Diazepam CLASS | Benzodiazepine, sedative hypnotic, anticonvulsant |
| Diazepam MECHANISM OF ACTION | Potentiates effects of inhibitory neurotransmitters. Raises seizure threshold. Induces amnesia and sedation. |
| Diazepam INDICATIONS | anxiety, alcohol withdrawal, muscle relaxant, seizure activity, agitation. Analgesia for medical procedures. |
| Diazepam CONTRAINDICATIONS | glaucoma, coma, shock, substance abuse, head injury |
| Diazepam ADVERSE REACTIONS | Respiratory depression, hypotension. Drowsiness, nausea, confusion, |
| Diazepam INCOMPATABILITIES/DRUG INTERACTIONS | Incompatible with most drugs, fluids. |
| Diazepam DOSE/ROUTE Adult, seizure activity | 5-10mg IV q 10-15 minutes prn. Max dose 30mg. |
| Diazepam DOSE/ROUTE Adult, cardioversion sedation | 5-15mg IV over 5-10 minutes prior to cardioversion. |
| Diazepam DOSE/ROUTE Pediatric, seizure activity | 0.2-0.5mg slowly q 2-5 minutes up to 5mg. max dose 10mg/kg. |
| Diazepam DOSE/ROUTE Pediatric, rectally | 0.5 mg/kg via 2’’ rectal catheter and flush with 2-3ml of air after administration. |
| Diazepam ONSET OF ACTION | 5 minutes |
| Diazepam PEAK EFFECTS | minutes |
| Diazepam DURATION OF ACTION | 50 minutes |
| Diazepam AZ DRUG BOX SUPPLY RANGE | 20mg. Rectal 20mg (optional) |
| Morphine GENERIC NAME | Morphine Sulfate |
| Morphine BRAND NAME | Astramorph/pf |
| Morphine CLASS | Opioid analgesic (schedule II narcotic) |
| Morphine MECHANISM OF ACTION | Alleviates pain through CNS action, Suppresses fear and anxiety centers in brain |
| Morphine INDICATIONS | CHF, pulmonary edema, chest pain associated with acute MI, analgesia for pain |
| Morphine CONTRAINDICATIONS | depressed respiratory drive, hypotension, undiagnosed abdominal pain, decreased LOC, Shock, |
| Morphine ADVERSE REACTIONS | Respiratory depression, hypotension, decreased LOC, N/V, Bradycardia, tachycardia, syncope |
| Morphine INCOMPATABILITIES/DRUG INTERACTIONS | CNS depressant may potentiate effects of morphine. MAOIs may cause paradoxical excitation. |
| Morphine DOSE/ROUTE Adult Initial dose | 2-4 mg IV. |
| Morphine DOSE/ROUTE Repeat dose | 2-8 mg at 5-15 minute intervals. |
| Morphine DOSE/ROUTE Pediatric | .1-.2 mg/kg per dose via IV. IO. IM, or SC; Maximum dose of 5mg. |
| Morphine ONSET OF ACTION | Immediate |
| Morphine PEAK EFFECTS | 20 minutes |
| Morphine DURATION OF ACTION | 7 hours |
| Morphine AZ DRUG BOX SUPPLY RANGE | 20mg |
Created by:
klindley
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