Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Toxicology Introduct

Introductory material for toxicology final

QuestionAnswer
"Toxicology" Study of Toxins
"Toxicant" Any poison
"Toxin" Poison made by living thing
"Toxcitity" Inherant biologic properties
"Hazard" Toxicity + Environment
"Toxicosis" Toxicant induced disease
"Xenobiotic Agent" Foreign substance
"Bioactivity" Metabolism to toxic agent
LD50 Less usefull than LD5. Only works in parallel curves.
Acute Treatment (1-3) 1. Get info (what, quantity, when, poison control for toxic profile). 2. Vomit (ipecac, mustard powder unless in coma, seizures, STRONG acid or base, petroleum distillates, heart disease, pregnancy or strychnine). 3. Absorbants: activated charcoal
Acute Treatment (4-5) 4. Decontaminate skin and eyes. 5. Get help
Professional Acute Treatment (0-1) 0. Emergency (coma, excess activation, arrythmias, metabolic acidosis, seizures, GI) 1. Initial exam (get specimen, physical exam)
Professional Acute Treatment (2-3) 2. Remove unabsorbed toxin via emesis (ipecac oral or apomorphine IV, gastric lavage (tube), cathartic (Na2SO4 and Mg2SO4 to increase elimination from GI), Absorb (activated charcoal)) 3. Antidotes (inverse graph between plasma concentration and time)
Professional Acute Treatment (4) 4. Support (most important, respiratory, circulatory (shock), temperature, pain)
Professional Acute Treatment (5) 5. Increase elimination (forced diuresis : increased fluid volume, change urinary pH : ion trapping = WA increase pH : NaHCO3, WB decrease pH : Na4Cl2, peritoneal dialysis : ion trapping, fluid into peritoneum, hemodialysis : slow elimination : small MW)
Determinants of Damage Dose, nature, tissue and cell characteristics (metabolic enzymes, protecitve mechanisms : GSH, antioxidants, functional reserve, regenerative abilities, rate, progress : inflammation)
Created by: chavezc3