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Cardio Drugs SE

Side Effects of Cardio Drugs

QuestionAnswer
Bile Acid Binding Resins SE: bloating, dyspepsia, constipation
Statins SE: Myopathy (dose related, drugs interactions involved), hepatotoxic
Cholesterol Absorption Blockers SE: RARE allergic rxn
Niacin (Nicotinic Acid) SE: Flushing, hepatotoxic, insulin-resistance, gout, GI
Nitrates SE: headache (everyone gets, will go away), flushing, hypotension
B-adrenergic Blockers SE: cardiac effects, bronchoconstriction, lethargy, fatigue, mental depression, nightmares, hypoglycemia
Ca Channel Blockers SE: headache, dizzy, flushing, hypotension, leg edema, V = constipation and nausea
Ranolazine SE (rare): dizzy, headache, constipation, nausea
Aspirin SE: risk of bleeding, allergy in some
ADP Inhibitors SE: neutropenia, thrombotic thrombocytopenic purpura, GI bleed (less than aspirin)
GP IIb/IIIa Receptor Inhibitor SE: thrombocytopenia, bleeding
Heparin SE: bleeding, thrombocytopenia (less is LMWH)
Fondaparinux SE: bleeding (less than Heparin)
Direct Thrombin Inhib SE: bleeding, unlikely to cause thrombocytopenia (low platelet #)
Fibrinolytic (TPA) SE: bleeding, stroke (esp w/heparin)
Analgesics SE: hypotension, resp depression, vomiting
Renin Angiotensin Inhib SE: hypotension, cough (ACEI), angioedema (ACEI, rare)
Oral X-Coags SE: bleeding, skin necrosis, MANY drug interactions
Loop Diuretics SE: volume and K (can get lethal arrhythmias) depletion, metabolic alkalosis
Thiazide Diuretics SE: volume depletion, K depletion, increase uric acid and glucose (make gout and diabetes worse, not cause them)
K+ Sparing Diuretics SE: Hyperkalemia (good @ stopping loss of K), GI
Aldosterone Antagonists SE: hyperkalemia, gynecomastia, impotence (spironolactone) and menstrual irregularities(spironolactone)
Renin Angiotensin Inhibitors (HF) SE: hypotension, cough (ACEI) and angioedema (ACEI, rare) ARB have less SE
Direct Arterial Vasodilators SE: headache, dizzy, tachy, edema
Digoxin SE: anorexia, nausea, vomit, blurry, arryths
B agonists SE: tachy, aryth
Phosphodiesterase Inhibs SE: hypotense, arrhyth (less so than digoxin)
Nesiritide SE: hypotense, increased plasma creatine
Aliskiren SE: mild, short lived, diarrhea in some, allergic rx rare but need withdrawal, Not in preggers
Created by: chavezc3