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Cardio Drugs SE
Side Effects of Cardio Drugs
| Question | Answer |
|---|---|
| Bile Acid Binding Resins | SE: bloating, dyspepsia, constipation |
| Statins | SE: Myopathy (dose related, drugs interactions involved), hepatotoxic |
| Cholesterol Absorption Blockers | SE: RARE allergic rxn |
| Niacin (Nicotinic Acid) | SE: Flushing, hepatotoxic, insulin-resistance, gout, GI |
| Nitrates | SE: headache (everyone gets, will go away), flushing, hypotension |
| B-adrenergic Blockers | SE: cardiac effects, bronchoconstriction, lethargy, fatigue, mental depression, nightmares, hypoglycemia |
| Ca Channel Blockers | SE: headache, dizzy, flushing, hypotension, leg edema, V = constipation and nausea |
| Ranolazine | SE (rare): dizzy, headache, constipation, nausea |
| Aspirin | SE: risk of bleeding, allergy in some |
| ADP Inhibitors | SE: neutropenia, thrombotic thrombocytopenic purpura, GI bleed (less than aspirin) |
| GP IIb/IIIa Receptor Inhibitor | SE: thrombocytopenia, bleeding |
| Heparin | SE: bleeding, thrombocytopenia (less is LMWH) |
| Fondaparinux | SE: bleeding (less than Heparin) |
| Direct Thrombin Inhib | SE: bleeding, unlikely to cause thrombocytopenia (low platelet #) |
| Fibrinolytic (TPA) | SE: bleeding, stroke (esp w/heparin) |
| Analgesics | SE: hypotension, resp depression, vomiting |
| Renin Angiotensin Inhib | SE: hypotension, cough (ACEI), angioedema (ACEI, rare) |
| Oral X-Coags | SE: bleeding, skin necrosis, MANY drug interactions |
| Loop Diuretics | SE: volume and K (can get lethal arrhythmias) depletion, metabolic alkalosis |
| Thiazide Diuretics | SE: volume depletion, K depletion, increase uric acid and glucose (make gout and diabetes worse, not cause them) |
| K+ Sparing Diuretics | SE: Hyperkalemia (good @ stopping loss of K), GI |
| Aldosterone Antagonists | SE: hyperkalemia, gynecomastia, impotence (spironolactone) and menstrual irregularities(spironolactone) |
| Renin Angiotensin Inhibitors (HF) | SE: hypotension, cough (ACEI) and angioedema (ACEI, rare) ARB have less SE |
| Direct Arterial Vasodilators | SE: headache, dizzy, tachy, edema |
| Digoxin | SE: anorexia, nausea, vomit, blurry, arryths |
| B agonists | SE: tachy, aryth |
| Phosphodiesterase Inhibs | SE: hypotense, arrhyth (less so than digoxin) |
| Nesiritide | SE: hypotense, increased plasma creatine |
| Aliskiren | SE: mild, short lived, diarrhea in some, allergic rx rare but need withdrawal, Not in preggers |