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UTA NURS 4581 Meds 1

UTA NURS 4581 Adults with Complex Needs Exam 1 Meds

QuestionAnswer
atorvastatin (Lipitor) classification and use HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
fluvastatin (Lescol) classification and use HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
lovastatin (Mevacor) classification and use HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
pitavastatin (Livalo) classification and use HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
pravastatin (Pravachol) classification and use HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
simvastatin (Zocor) classification and use HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
rosuvastatin (Crestor) classification and use HMG-CoA Reductase Inhibitor (Statin); used to treat hyperlipidemia by restricting lipoprotein production
niacin (Nicobid, Niaspan) classification and use Niacin; used to treat hyperlipidemia by restricting lipoprotein production
nicotinic acid (Slo-Niacin, Novo-Niacin) classification and use Niacin; used to treat hyperlipidemia by restricting lipoprotein production
fenofibrate (TriCor) classification and use Fibric Acid Derivative; used to treat hyperlipidemia by restricting lipoprotein production
gemfibrozil (Lopid) classification and use Fibric Acid Derivative; used to treat hyperlipidemia by restricting lipoprotein production
cholestyramine (Questran) classification and use Bile-Acid Sequestrant; used to treat hyperlipidemia by increasing lipoprotein removal
colesevelam (WelChol) classification and use Bile-Acid Sequestrant; used to treat hyperlipidemia by increasing lipoprotein removal
colestipol (Colestid) classification and use Bile-Acid Sequestrant; used to treat hyperlipidemia by increasing lipoprotein removal
ezetimibe (Zetia) classification and use Cholesterol Absorption Inhibitor; used to treat hyperlipidemia by decreasing cholesterol absorption
HMG-CoA Reductase Inhibitors (Statins) Mechanism of Action and Effects Block synthesis of cholesterol and increase LDL receptors in liver, ↓ LDL, ↓ Triglycerides, ↑ HDL
HMG-CoA Reductase Inhibitors (Statins) Nursing Considerations Well tolerated with few side effects. Monitor liver enzymes and creatine kinase (if muscle weakness or pain occurs).
Niacin Mechanism of Action and Effects Inhibits synthesis and secretion of VLDL and LDL, ↓ LDL, ↓ Triglycerides, ↑ HDL
Niacin Nursing Considerations Most side effects subside with time; decreased liver function may occur with high doses. Taking aspirin or NSAID 30 min before drug may prevent flushing; take drug with food. Treat elevated homocysteine levels with folic acid.
Fibric Acid Derivatives Mechanism of Action and Effects Decrease hepatic synthesis and secretion of VLDL; ↓ LDL; ↓ Triglycerides; ↑ HDL
Fibric Acid Derivatives Nursing Considerations May ↑ effects of warfarin (Coumadin) and some antihyperglycemic drugs. When used in combination with statins, may increase adverse effects of statins, especially myopathy.
Bile-Acid Sequestrants Mechanism of Action and Effects Bind with bile acids in intestine, forming insoluble complex and excreted in feces, resulting in removal of LDL and cholesterol; ↓ LDL
Bile-Acid Sequestrants Nursing Considerations Effective and safe for long-term use; side effects diminish with time. Interfere with absorption of many drugs (e.g., digoxin, thiazide diuretics, warfarin, some antibiotics [e.g., penicillins]).
Cholesterol Absorption Inhibitor Mechanism of Action and Effects Inhibits the intestinal absorption of cholesterol; ↓ LDL; ↑ HDL
Cholesterol Absorption Inhibitor Nursing Considerations When used with a statin, LDL is further reduced. Should not be used by patients with liver impairment.
Simvastatin (Zocor) Drug Alert Increased risk for rhabdomyolysis when also used with gemfibrozil (Lopid) or niacin. Signs of rhabdomyolysis: ↑ creatine kinase levels, muscle tenderness.
Niacin (Niaspan) Drug Alert Instruct patient that flushing (especially of face and neck) may occur within 20 minutes after taking drug and may last for 30 to 60 minutes. Can premedicate with aspirin or NSAID 30 minutes before to reduce flushing.
Gemfibrozil (Lopid) Drug Alert May increase the risk of bleeding in patients taking warfarin (Coumadin). May increase the effects of antihyperglycemic drugs (e.g., repaglinide [Prandin]).
Nitrates mechanism of action Promote peripheral vasodilation, decreasing preload and afterload. Coronary artery vasodilation.
β-Adrenergic blocker mechanism of action Inhibit sympathetic nervous stimulation of the heart. Reduce heart rate, contractility, and blood pressure. Decrease afterload.
Calcium channel blockers Prevent calcium entry into vascular smooth muscle cells and myocytes (cardiac cells). Coronary and peripheral vasodilation. Reduce heart rate, contractility, and blood pressure.
ACE Inhibitor mechanism of action Prevent conversion of angiotensin I to angiotensin II resulting in vasodilation. Decrease endothelial dysfunction. Useful with heart failure, tachycardia, MI, hypertension, diabetes, and chronic kidney disease
Sublingual nitroglycerin (Nitrostat, NitroQuick) classification and use Nitrate; used to treat chronic stable angina and acute coronary syndrome
Translingual spray nitroglycerin (Nitrolingual) classification and use Nitrate; used to treat chronic stable angina and acute coronary syndrome
Nitroglycerin ointment (Nitro-Bid, Nitrol) classification and use Nitrate; used to treat chronic stable angina and acute coronary syndrome
Transdermal nitroglycerin (Transderm-Nitro, Minitran) classification and use Nitrate; used to treat chronic stable angina and acute coronary syndrome
Extended-release buccal tablets (Nitrogard) classification and use Nitrate; used to treat chronic stable angina and acute coronary syndrome
Isosorbide dinitrate (Isordil, Sorbitrate) classification and use Nitrate; used to treat chronic stable angina and acute coronary syndrome
IV nitroglycerin (Nitro-Bid IV, Tridil) classification and use Nitrate; used to treat chronic stable angina and acute coronary syndrome
atenolol (Tenormin) classification and use β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary syndrome
carvedilol (Coreg) classification and use β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary syndrome
esmolol (Brevibloc) classification and use β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary syndrome
metoprolol (Lopressor) classification and use β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary syndrome
nadolol (Corgard) classification and use β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary syndrome
propranolol (Inderal) classification and use β-Adrenergic Blockers; used to treat chronic stable angina and acute coronary syndrome
amlodipine (Norvasc) classification and use Calcium Channel Blocker; used to treat chronic stable angina and acute coronary syndrome
diltiazem (Cardizem) classification and use Calcium Channel Blocker; used to treat chronic stable angina and acute coronary syndrome
felodipine (Plendil) classification and use Calcium Channel Blocker; used to treat chronic stable angina and acute coronary syndrome
nifedipine (Procardia) classification and use Calcium Channel Blocker; used to treat chronic stable angina and acute coronary syndrome
nicardipine (Cardene) classification and use Calcium Channel Blocker; used to treat chronic stable angina and acute coronary syndrome
verapamil (Calan, Isoptin) classification and use Calcium Channel Blocker; used to treat chronic stable angina and acute coronary syndrome
captopril (Capoten) classification and use ACE Inhibitor; used to treat chronic stable angina and acute coronary syndrome
enalapril (Vasotec) classification and use ACE Inhibitor; used to treat chronic stable angina and acute coronary syndrome
Nitroglycerin Drug Alert Tablet or spray needs to be administered under the tongue. Instruct patient not to combine with drugs used for erectile dysfunction (e.g., sildenafil [Viagra]). Monitor for orthostatic hypotension because it may occur after administration.
recombinant plasminogen activator (rPA; reteplase [Retavase]) classification and use fibrinolytic therapy; used in ST-segement-elevation MI (STEMI) to break up fibrin meshwork in clots
tissue plasminogen activator (tPA; alteplase [Activase]) classification and use fibrinolytic therapy; used in ST-segement-elevation MI (STEMI) to break up fibrin meshwork in clots
TNK-tPA (tenecteplase [TNKase]) classification and use fibrinolytic therapy; used in ST-segement-elevation MI (STEMI) to break up fibrin meshwork in clots
Fibrinolytic Drug Alert If signs and symptoms of major bleeding occur (e.g., drop in BP, an increase in HR, a sudden change in the patient's level of consciousness, blood in the urine or stool), stop the therapy and notify the physician.
Created by: CocoDiva