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Immunopathology

QuestionAnswer
How does mycobacterium evade the immune system? Modifies the phagosome surface so it doesn't fuse with lysosomes
Sepsis can be caused from what, on a G-ve bacterium? Lipopolysaccharide layer
How do non allergic people react to allergens? Respond weakly with IgG
How do allergic people respond to allergens? Produce lots of IgE
What are recruited (& from where) in the delayed response to allergens? Eosinophils from the bone marrow
What is the heritable factor in autoimmunity HLA / MHC presenting self antigen
What is left to complete chance in autoimmunity? A BCR/TCR that can recognise self antigens
What can a microbial attack cause in autoimmunity? Molecular mimicry of self antigens
What cells does multiple sclerosis(MS) affect? Oligodendrocytes
What does myasthenia gravis do? Antibodies block the acetylcholine receptors on the dendrites of neurons
Why is HIV difficult to cure in people? High mutation rate means the genome is always changing
Created by: Jake_Bark