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Cogs17 Course Review

Cogs17 Vocab

QuestionAnswer
Connecting to the SAME side vs. connecting to the OPPOSITE side Ipsilateral / Contralateral
Towards the sides vs. toward the middle Lateral / Medial
Towards the stomach or the bottom of the human head vs. towards the back or the top of the human head Ventral / Dorsal
A structure above another vs. one below another Superior / Inferior
Planes through head as seen from the front vs. the side vs. above Coronal / Saggital / Horizontal
Division of the Forebrain that ultimately becomes the Thalamus, Hypothalamus and the eye Diencephalon
Division of the Forebrain that ultimately becomes the Cerebral Cortex, Basal Ganglia, Limbic System, etc. Telencephaon
Hindbrain structure, controls vital reflexes Medulla
Hindbrain structure, acts as bridge between Hindbrain and higher centers Pons
Hindbrain structure, involved primarily with guided, timed movements Cerebellum
Network of cells moving through hind- and mid-brain, involved in arousal Reticular Formation
Core strip of cells through hind-and mid-brain, involved in sleep Raphe System
Midbrain structure involved in motor processes Tegmentum
Midbrain structure involved in sensory processes, includes Superior (visual) and Inferior (auditory) Colliculi Tectum
Forebrain structure, oversees 4Fs, temperature, clock; communicates with and through the endrocrine system Hypothalamus
Forebrain structure, "Master Gland", stimulated by Hypothalamus Pituitary Gland
Forebrain structure, a principal stop along most sensory pathways Thalamus
A set of forebrain structures involved in motivation and emotional expression Limbic System
Forebrain structure, involved in the formation of new memories Hippocampus
Forebrain structure, associated especially with anger and fear Amygdala
Forebrain structure, layer mediating between cortex and lower systems, especially for socio-emotional evaluation Cingulate Gyrus
Forebrain structure, receives smell info from olfactory receptors Olfactory Bulb
Forebrain structure including Caudate Nucleus, Putamen & Globus Pallidus, involved in control of movement Basal Ganglia
Forebrain structure including Nucleus Basalis, involved in arousal and attention Basal Forebrain
Forebrain structure, outer "bark" of brain, 6-layered, highly convoluted Cerebral Cortex
Set of axons connecting the two cerebral hemispheres Corpus Callosum
Lobe of the cortex, posterior, primarily involved in visual processing, including V1 (Striate Cortex) Occipital Lobe
Lobe of the cortex, lateral, primarily involved in auditory processing (e.g. A1 and Wernicke's) and higher visual (IT) Temporal Lobe
Lobe of the cortex posterior to the Central Sulcus, primarily involved in somatosensory and visio-spatial maps Parietal Lobe
Lobe of the cortex anterior to Central Sulcus, motor control including Broca's Area and, in Prefrontal Area,strategy & self control Frontal Lobe
Part of the CNS other than the brain Spinal Cord
Part of the Spinal Cord through which sensory info enters. vs. through which motor info exits Dorsal Root / Ventral Root
"Law" governing above directions of information flow Bell-Magendie Law
Area of the Spinal Cord (as seen in cross-section) consisting of soma vs. of myelinated axons Grey / White Matter
Tube through core of Spinal Cord containing fluid Central Canal
Four hollow chambers (plus aqueducts) in brain that produce the fluid that feeds, cleans and cushions brain Ventricles
Fluid, produced by ventricles, found within Spinal Cord and in covering surrounding CNS Cerebral Spinal Fluid (CSF)
Three-layered (Dura-, Fluid-filled Arachnoid- and Pia-Mater) protective covering that surrounds CNS Meninges
Semi-permeable barrier, controls what chemicals enter brain, created by closing gaps between capillaries' endothelial cells Blood Brain Barrier
That part of the PNS that is responsible for the body's interaction with the environment Somatic Nervous System
That part of the PNS that is responsible for assessing and maintaining the body's internal environment Autonomic Nervous System
That part of the ANS that produces the "fight or flight" response vs. that which facilitates relaxation and replenishment Sympathetic / Parasympathetic NS
Extreme compensatory response of one system to extreme activation of the other - can lead to fainting, ulcers, voodoo death Parasympathetic Rebound
Cells in the Nervous System responsible for information transmission Neurons
Cells in the Nervous System responsible for support, feeding, recycling, development, etc Glial cells
Organelles in a cell that are the site of protein production, crucial to much neural functioning Ribosomes
Organelles in a cell that are the source of energy (ATP) to power active (vs. passive) funcitons in cell Mitochondria
Processes (branches) of a neuron that receive the incoming message vs. the one that releases the outgoing message Dendrites / Axon
Difference in the amount of a given chemical inside/outside a cell vs. a difference in charge inside/outside a cell Concentration / Electical Gradient
Symbols for 4 key chemical elements in neural functioning - including 3 positive ions, 1 negative ion Na+, K+, Ca++, Cl-
Name for and amount of difference in charge inside/outside cell, in millivolts (mV), in a polarized cell ready to fire Resting Potential (-70mV)
Energy-requiring pump that helps restore membrane potential after cell fires Sodium-Potassium Pump
A sequence of depolarization that moves along an axon, resulting in the all-or-nothing release of NT Action Potential
Section of axon where depolarization sequence begins Axon Hillock
A greater or lesser change in the polarity of a neuron that results in a greater or lesser release of NT Graded Potential
Propagation of info down an axon by way of chemical gates opening/closing vs. by flow of electrons Ionic / Electrical Conduction
"Jumping" electrical conduction that occurs in myelinated axons Saltatory Conduction
Glia cells wrapping around sections of an axon to insulate it and speed its information transmission Myelination
Gaps between myelin sheaths on an axon Nodes of Ranvier
Disease that destroys myelin; no ion gates under sheath so neuron cannot fire Multiple Sclerosis (MS)
Period following an Action Potential during which the cell cannot (or is more difficult to) fire Refractory Period
The event in which one cell releases NT and that NT affects another cell Synapse
The gap between cells across which NT passively floats Synaptic Cleft
The cell that releases the NT vs. the cell that receives the NT Pre- / Post Synaptic Cell
The end of the axon from which NT is released, also called "button" or "end bulb" Pre-Synaptic Terminal
Packets of NT released by a neuron Vesicles
The release of NT into cleft via its packet opening at a Fusion Pore in the cell's membrane Exocytosis
Area, usually on a dendrite, that is specialized for the attachment of NT Receptor Site
An increase vs. a decrease in a cell's likelihood of releasing neurotransmitter EPSP / IPSP
Less polarized, less difference between inside of cell and outside of cell vs. more difference Hyper / Hypo-Polarization
Cumulative effect of the activity of multiple Presynaptic cells; Can be temporal or spatial Summation
When NT has direct effect on ion channels in Postsynaptic cell vs. indirect effects via internal metabolic processes Ionotropic / Metabotropic
Chemical in Postsynaptic cell involved in energy-requiring processes (including altering ion channels) triggered by NT Second Messenger
Chemicals released by Presynaptic cells that directly affect local Postsynaptic cells vs. ones that widely influence neural activity Neuro-transmitters / -modulators
Chemical (endogenous or man-made) that acts to facilitate (via imitation or enhancement) vs. to block the effects of specific NTs Agonist / Antagonist
Process by which NTs or their components re-enter the Presynaptic cell for re-use. Reuptake
Enzyme in cleft that breaks down Acetylcholine Acetylcholinesterase
Site on Presynaptic terminal that reacts to that cell's own NT, usually acting to turn off/down that cell's further NT release Auto-Receptors
Synapses at Presynaptic terminal that reacts to NT from other cell, excitatory or inhibitory Axoaxonic Synapses
Epinepherine (Adrenalin), Testosterone, Estrogen, Oxytocin, Insulin, Cortisol 6 Hormones
Acetylcholine ACh Acetylcholine
Dopamine DA Dopamine
Serotonin 5-HT Serotonin
Norepinepherin NE Norepinepherin
Adrenalin Epinepherine
Glutamate Glutamate
GABA GABA
Substance P Substance P
Endorphins Endorphins
In the new embryo, the outermost layer of cells - becomes the nervous system and skin Ectoderm
In the growing (wormlike) embryo, the surface along the back that thickens and hardens Neural Plate
A pair of ridges all along the above that begin to curl towards each other Neural Folds
The long hollow chamber that is formed when the above meet and fuse, inner surface becomes the CNS Neural Tube
Outer surface of the above ridges that separate off and become the PNS Neural Crest
A pathological condition involving a failure of the edges above to completely fuse, leading to birth defects or death Spina Bifida
The original type of cells in this area that undergo division to populate nervous system Stem Cells
Cell division that produces two identical offspring vs. produces one identical and one new (neuron or glial) cell Symmetrical / Asymmetrical Division
An early type of glial cell that extends its processes out like wheel spokes for the developing neurons to migrate along Radial Glia
Glia cells that are positioned to direct growing axons towards their target cells Guidepost cells
Cell Death as determined by "suicide genes" that cause developing neurons to package their contents & destroy themselves Apotosis
Chemicals that attract/repel Axon growth, help prevent cell death, and/or promote Axonal branching Neurotrophins
One type of the above, from muscles & organs, that promotes survival and growth of axons in the brain and Sympathetic NS Nerve Growth Factor (NGF)
Newly formed axonal branch that replaces another (that has died off) at a synapse Collateral sprout
New outgrowths on, or subdividing of, the processes that receive NT, in response to an enriched enviornment, learning, etc. Dendritic spines / branching
The production of new cells Proliferation
The movement of cells from their place of origin to their later position Migration
The formation of new synapses Synaptogenesis
A mnemonic for the rule that co-activated cells tend to be strengthened in their connectivity and out-compete neighboring cells Fire together > Wire together
The production of new cells Proliferation
The movement of cells from their place of origin to their later position Migration
The formation of new synapses Synaptogenesis
A mnemonic for the rule that co-activated cells tend to be strengthened in their connectivity and out-compete neighboring cells Fire together > Wire together
Convergence (or Summation) When multiple pre-synaptic cells all communicate to one post-synaptic cell
Divergence When one presynaptic cell communicates to many post-synaptic cells
Receptive Field Set of receptors whose actitvity influences the activity of target cell
Excitatory Center- Inhibitory Surround Type of above: stimulating center increases target response, non-center decreases it
Topological Type of map that preserves spatial relaitonships (as along a sensory surface)
Magnification In cortex, disproportionate enlargement of the rep. of a sensory area of low convergence
Module An area of the brain specialized for processing one particular type of information
The Binding Problem The problem posed by having several of the above, and yet perceiving wholes
Retina Rear layers of neurons in the eyeball
Receptors (Rods & Cones) Cells that respond to light; show spontaneous, graded release of inhibitory NT
Rods Above that are convergent, sensitive to motion & low light, mainly in periphery
Cones Above that connect few:1, sensitive to color & detail, dispersed plus conc'd in center
Fovea Central area of above receptor types only, connected 1:1 for highest acuity
Bipolars Next cell in pathway, spontaneous, graded potentials, release excitatory NT
Horizontals Inter-neurons that modify reaction of above, implicated in color opponency
Ganglions Next cell in pathway, action potentials, release excitatory NT
Optic Nerve Formed of axons of the above
Optic Disc Place where above leaves eye for brain, also called "Blind Spot"
Amacrines Inter-neurons that modify reaction of above, implicated in contrast effects
Dim Level of light (bright vs. dim?) that results in greatest release of NT from receptors
Bright Level of light (bright vs. dim?) that results in greatest release of NT from bipolars
Acuity High-detail discrimination, as from low convergence, that retains info on diffs
Sensitivity High likelihood of detection, as from high convergence that crosses next cell's threshold
Lateral Inhibition Cell activity resulting in release of inhibitory NT to cells orthogonal to info pathway
Simultaneous Contrast Illusion created by above that alters perception of central grey depending on its surround
Uni-directional Direction of inhibition (uni- or bi-directional?) in direction-senstive motion circuit
Lateral Geniculate Nuc or LGN Nucleus in Thalamus that processes most visual information from eye
Column In cortex, set of cells, in 6 layers, that all respond to the same preferred stimulus
Hyper-Column In cortex, set of cells that all have same RF and include set of orientation cols & blobs
Retinotopic Map Topological map that preserves spatial relationships found on Retina
A1 or Striate Cortex Primary Projection area for vision in Occipital Lobe of cortex
Parvocellular Pathway Visual pathway specialized for color and detail, that "flows" along bottom of cortex
Temporal Pathway Above also called...because it terminates in this lobe of the cortex
What/Who Pathway Above also called…because it conveys info that helps you to identify a stimulus or individual
Parvocellular or X Ganglions Small ganglion cells that begin this pathway, with small RFs & sustained response
Magnocellular Pathway Visual pathway specialized for motion and localization,"flows" along top part of cortex
Parietal Pathway Above also called …because it terminates in this lobe of the cortex
Where/How Pathway Above also called…because it conveys info that helps locate & interact w/stimuli
Magnocellular or Y Ganglions Large ganglion cells that begin this pathway, with large RFs & transient response
Superior Colliculus Nucleus in Midbrain in this path, processes some visual (esp motion) info from eye
Blindsight Tho vis cortex damaged & no visual experience, midbrain enables some vis localization
Trichromatic Color Vision Color coding per ratio of activity of 3 cone types reponding to 3 overlapping ranges of freqs
Color Opponency Recoding of above, via lateral inhibition from Horizontal cells, into Red/Green & Blue/Yellow
Opponent Cells LGN or Ganglions with R+G-, G+R-, B+Y- or Y+B- receptive fields
Color Constancy V4-mediated process that enables ID of color under diff light conditions (AKA "Retinex Theo")
Simple Cells Cells in V1 that respond to line, or gradient, oriented in particular direction
Complex Cells Cells in V2 that give best response to moving lines of particular orientation
Spatial Frequencies Number of dark/light changes per degree of visual angle
High Frequency Frequency gradients (high vs. low?) that V1 cells in Parvo path are most sensitive to
Low Frequency Frequency gradients (high vs. low?) that V1 cells in Magno path are most sensitive to
Inferior Temporal or IT End of Parvo pathway, includes cells that prefer hand, face, other complex stim
Prosopagnosia Deficit from damage to Fusiform Gyrus, patient cannot recognize familiar faces
MT Cortex with direction-sensitive cells, responds best to stimulus moving across retina
MST Cort4x with optic-flow detectors that repond best to contraction/expansion of whole scene
Disparity Detectors In V2 or MT, cells that respond to degrees of diff between location of an image on 2 retina
Tympanic Membrane Membrane vibrated by air molecules moving down Auditory Canal
Ossicles Three tiny bones linked into lever system, amplify vibrations of above
Oval Window Membrane vibrated by third bone above, initiating vibration of…
Cochlear Fluid Thick, incompressible, potassium-rich fluid that fills…
Cochlea Coiled, three-chambered tube in Inner Ear which contains…
Organ of Corti Section of central chamber where Receptor Cells are found
Basilar Mambrane Membrane that runs along floor of above structure, moves up and down
Tectorial Membrane Membrane that runs along roof of above structure, moves forward & back
Hair Cells Auditory receptor cells that are deformed between the above two membranes
Cillia Tiny "hairs" extending from above cells whose deformation initiates transduction
K+ Ion that enters receptor, descreasing its polarity
Ca++ Ion that enters receptor, causing chain reaction that results in release of NT
Glutamate NT released by auditory receptors
Graded Potential Type of change in polarity in receptors (graded vs. action potential?)
Spiral Ganglions or ANFs Cells to which Receptors communicate, whose axons exit to brain
Action Potential Type of change in polarity in these cells (graded vs. action potential?)
Place Coding Relative levels of activity across differentially-resonating Bas. Memb. code freq
Temporal Coding Rate of oscillation of Bas. Membrane codes freq per rate of Auditory Nerve Firing
Refractory Period Time during which Auditory Nerve Fibers cannot fire next Action Potential
Volley Principle Since each above can only fire 1/1000sec, must work together at alt. intervals
Phase Locked Ganglions involved in above can all only fire at the same phase (e.g.) peak of input wave.
Amplitude Differences Diffs used for localization, caused by "head shadow" attenuating high freqs
Phase Differences Diffs used for localization, comparing peak & trough of lower frequencies
Timing Differences Diffs used for localization, per race of left vs. right Onset signals to Superior Olive
Inner Hair Cells Receptor Cells that show divergent connectivity, for detail freq discrimination
Outer Hair Cells Receptor Cells that show convergent connectivity, for loudness discrimination
Auditory Nerve Axons of next cells in path form this nerve
8th Cranial Nerve Above is part of (?) Cranial Nerve
Cochlear Nucleus Next synapse in Medulla, beginning of separate information pathways
Primary Like Cell Cell in above nucleus that duplicates the incoming signal
Tonotopic Map Above helps generate what kind of map that reps low>high frequency across cell array
Onset Cell Cell in above nucleus that transforms incoming signal into a transient burst
Build Up Cell Cell in above that transforms incoming signal into one of graded, increasing amp
Monaural When information from only one ear is involved, as in the above
Binaural When info from both ears is combined, good for localization, as in the following…
Superior Olive Next auditory site, also in Medulla, responsible for Orienting Reflex
Inferior Colliculus Next auditory site, in Midbrain, where info integrated with visual at nearby site
Medial Geniculate Nuc or MGN Next auditory site, in Thalamus, site of among other things…
A1 Primary Projection Area for audition, in Temporal Lobe of cortex
A2 Secondary Auditory area in cortex
Wernicke's Area Area with critical role in the comprehension of speech, in left hemisphere
Music Type of complex auditory input processed by higher auditory centers in right hemi.
Hair Cells Type of receptor cells in Vestibular system
K+ Ion, when not/allowed to enter cell, changes receptor's polarity
Spontaneous Firing Rate Changes in velocity & orientation alter this kind of firing rate
Otolith Organ Where receptors respond to head tilt via gravity-induced deformation by crystals
Semi-Circular Canals Three fluid-filled tubes that detect changes in angular acceleration
Motion Sickness Effect when visual and/or motor feedback is inconsistent with vestibular info
8th Cranial Nerve Cranial nerve (?) shared with audition
Free Nerve Endings Class of receptors that respond to temp, pain, itch and hair follicle movement
Nociceptors Receptors in above class that respond to "noxious" (potentially damaging) stimuli
Encapsulated Endings Class of receptors that respond to touch and internal movement
Proprioception Detection of internal movement of muscles and organs
Action Potentials Type of response by above type of receptors (graded or action potentials?)
Selective Adaptation Process by which one type of receptor is fatigued, showing its role in coding
Ventral Posterior Nuc or VPN Nucleus of Thalamus in somatosensory pathway
Spinal Thalamic Pathway Path for pain and temperature info to brain, crossing over in Spinal Cord
Medial Lemniscal Pathway Path for touch and internal motion info to brain, crossing over in Brainstem
MLP Which of above paths tends to be myelinated
Brown-Sequard Sndrome When damage to one side of spine results in diff losses on ipsi- vs. contra-lateral sides
Post-Central Gyrus Location of Primary Projection Area (S1) for somatosensory info
Penfield Map Name of topological map of body surface found there
Hands and Mouth Parts of body that fill disproportionate areas of this map
Substance P Neurotransmitter released by pain receptors and other cells in pain pathway
Gate Theory Theory concerning the top-down blocking of pain info entering brain
Peri-Aquaductal Grey or PAG Midbrain area that is probably the source of this blocking
Endorphins "Endogenous morphines" released by above
Inhibitory Interneuron (SG) Type of inter-neuron in spine that responds to above input
Naloxone Opiate antagonist that reduces analgesic effects of morphine & acupuncture
Striate Muscles Type of muscle, made of parallel fibes, attached by tendons to bones
Flexors One type of above, that moves bone toward body, in antagonistic pair with…
Extensors …other type, that moves bone away from body
Neuro-Muscular Junction Where neuron releases NT that depolarizes muscle fiber cells > contraction
Acetylcholine ACh Neurotransmitter released by effector neurons to contract muscles
Sarcomere The contractile unit of a muscle fiber, consisting of…
Myosin Thick protein filament with knobby bead-like Cross Bridges along it, and…
Actin Thin braided protein filament, anchored to muscle, that above hook into & tighten
Spindle A proprioceptor that detects passive stretch of a muscle, triggering…
Stretch Reflex A mono-synaptic reflex that contracts muscle to counter passive stretch
Golgi Reflex A reflex triggered by Tendon Organs detecting excessive contraction in muscle
Pain Withdrawal Reflex A reflex triggered by pain detectors, rapidly removing skin from source of pain
Scratch Reflex A reflex involving an Oscillator Circuit producing a fixed-rate rhythm
Infant Reflexes Reflexes, such as "rooting" or "grasping", found in newborns
Primary Motor Cortex Area of cortex that includes body map, sends movement commands to Stem and Cord
Pre-Central Gyrus Location of above
Premotor Cortex Anterior to above, active during preparation to move, receives esp from Visua-Spatial areas
Mirror Cells Above includes cells that respond to image of self, or other, performing familiar manual task
Broca's Area Lateral area that plans articulation, helps generate gramatical sentences (esp in left hemi)
Supplementary Motor Cortex Dorsal to above, also active during prep, esp for rapid moves, receives from Parietal
Cortico-Spinal Pathway Fast, crossing paths from Pyramids in cortex, esp. for precise control of peripheral moves
Red Nucleus (of Tegmentum) Above stops at this Midbrain structure on way from Cortex to Medulla & Cord
Ventro-Medial Pathway Mainly ipsilateral pathways for posture & gross movement of neck, shoulders & trunk
Cerebellum "Little brain" involved esp in coordinated movement requiring aiming and timing
Ballistic Movements that occur very rapidly & generally cannot be altered once begun
Purkinje Cells "Telephone poles" in cerebellar cortex that help code time as distance
Parallel Fibers "Wires" in above whose action potentials release excitatory NT
Deep Nuclei Central areas that receive from "telephone poles" and send output to Brain/Cord
Basal Ganglia Set of forebrain structures controlling posture, muscle tone, & smooth movement
Parkinson's Disease Movement impairment, marked by rigidity, tremors etc, from degeneration of…
Substantia Nigra Midbrain structure whose dopaminergic axons synapse in Basal Ganglia
L-Dopa Precursor of dopamine, crosses barrier, converted by neurons into dopamine
Beta Activity EEG while awake/active, 18-24 Hz, Very high freq, very desynchronized
Alpha Activity EEG while awake/relaxed, 8-12 Hz, Like above, somewhat more sync’d
Theta Activity EEG during Sleep I, 4-7 Hz, Lower freq, still quite irregular, more sync'd
Delta Activity EEG during Sleep 3(&4), <4 Hz in less (&more) than 50% , Very low freq, very high voltage, very sync’d
Spindle and K Complex During Sleep 2, 2 types of intermittent bursts of high freq or voltage, as brain settles into deeper sleep
Slow Wave Sleep Another term for Sleep 3 & 4, re: its low frequency EEG and highly synchronized activity
REM (Rapid Eye Movement) Stage of Sleep associated with dreams
Paradoxical Sleep Another name for above due to its contradictory nature (active, desynch'd brain, but paralyzed body)
Atonia Condition in which Pons suppresses motor signals sent to Cord, so muscle action prohibited
PGO Wave Sequence of activation in Pons => (Lateral) Geniculate => Occipital Cortex that initiates dream sleep
ACh Excitatory neurotransmitter released by above to desychronize brain
90 Minutes Duration ( minutes) of one sleep cycle through Stages 1, 2, 3, 4, 3, 2, “Dream” sleep
REM Rebound Condition after sleep deprivation in which system attempts to enter “Dream” sleep more frequently
Suprachiasmatic Nuc (SCN) Location in Hypothalamus of Circadian Clock
Zeitgeber “Time Giver”, a stimulus, such a bright sunlight, that can reset Circadian Clock
Retino-Hypothalamic Path Path of Optic Nerve collateral that connects special visual receptors in eye directly to clock
Pineal Gland Gland that produces a hormone that impacts on Hypothalamus to increase sleepiness
Melatonin The hormone mentioned above, which can also be taken as a sleep aid.
Basal Forebrain Forebrain structure (anterior & dorsal to Hypothal) that modifies arousal in cortex
ACh Neurotransmitter released by above that increases cortical arousal
GABA Neurotransmitter released by above that decreases cortical arousal
Adenosine Chemical that builds up in cells, released as NT, inhibits release of above excitatory NT, promotes sleep
Caffeine Stimulant that blocks receptors for above, allowing continued cortical arousal
PreOptic Area Nucleus of Hypothalamus critical in initiating sleep (also assesses & regulates body temperature)
Raphe Nuclei Structure in Pons whose functions include shutting off REM sleep
Serotonin (5HT) Neurotransmitter released by above nuclei; very low in Slow Wave Sleep, very high at the end of REM
Reticular Formation “Net” from Medulla & Pons, for widespread arousal of Forebrain, esp Thalamus and Basal Forebrain
ACh and Glutamate Two neurotransmitters released by above, to alert brain
Locus Coeruleus (“Dark Blue Place”) An arousal center, active during new tasks , vigilance, memory formation
Norepinepherine (NE) Neurotransmitter released by above, absent during dreams; Amphetamines are antagonists for this NT
Organizing vs. Activating Effects of reproductive hormones on anatomy vs. on behavior
Estrogens vs. Androgens Class of reproductive hormones found in greater proportion in Females vs. in Males
XX vs. XY Sex chromosomes typical of Females vs. Males, which help determine gender
Wolffian vs. Muellerian Systems of ducts in fetus that become part of internal reproductive organs of Males vs. Females
Testosterone A Male hormone, produced by testes, responsible for development of Male anatomy and behavior
Anti-Muellerian Hormone Another Male hormone that inhibits development of Female system of internal ducts
Testis-Determining Factor (TDF) Enzyme produced by “switch” on Male chromosome that leads to the development of gender
Androgen-Insensitivity Condition in which genetic-male fetus does not respond to Male hormones and thus develops as Female
Turner’s Syndrome Condition in which fetus lacks Y Chromosome, develops internally & externally as infertile Female
Estradiol A Female hormone, (similar to Testosterone) that, once inside fetal cells, promotes Male development
Apha-Fetoprotein Chemical in fetal bood that prevents mother’s hormones from entering fetal cells and masculinizing fetus
Medial Preoptic Area (MPOA) Area of Hypothalamus w/receptor sites for Male hormones, esp active during Male sexual behavior
Sexually Dimorphic Nuc (SDN) Above includes this nucleus which is 2.5X larger in Males than Females
INAH3 Part of above nucleus that is smaller in both Females and Homosexual Males
Ventro-Medial H. (VMH), Area of Hypothalamus w/receptor sites for Female hormones, esp active during Female sexual behavior
Corpus Callosum Fibers connecting cortical hemispheres which is thicker in Females, who are thus less-lateralized
Gonadotropin-Releasing (GnRH) Hormones released by Hypothalamus causing Anterior Pituitary to release its reproductive hormones
LH and FSH Two Gonadotropic hormones that stimulate development and behavior in both genders
Androstenedione Male hormone released by Female Adrenal Glands, stimulates secondary hair growth & sexual behavior
Nucleus Accumbens Area near Basal Forebrain associated with the sensation of sexual pleasure
Dopamine Neurotransmitter released by above area in response to sexual stimulation
Oxytocin Hormone released by Posterior Pituitary at time of orgasm
Prolactin Hormone released by Anterior Pituitary for refractory period in Males and milk production in Females
Periaqueductal Gray Area Part of Tegmentum active especially in Females during sex
Endorphins Neurotransmitter released by above area, including to supress potential for pain
James-Lange Theory Theory that suggests emotion is an after-the-fact label we give to arousal and assoc'd behavior
Cannon-Bard Theory Theory: Once threat perceived (via Thalamus), emotion is simultaneous ANS activity & subjective experience
Papez Circuit Update of above that includes Limbic Syustem in circuit
Schater-Singer Theory Theory: Emotion is interaction between cognitive appraisal and autonomic/limbic activity
Amygdala Key Limbic structure implicated in interpreting valenced situations and coordinating an emotional response
Corticomdial Area Area of above, when stimulated, promotes attack
Lateral Nuclei Area of above responsible for coordinating Startle Reflex
Central & Basolateral Nuclei Areas of above involved in Coniditioned Fear and subsequent enhancement of Startle Reflex
Urbach-Weith Disease Degenerative calcium buildup in Amygdala that results in deficits in interpreting facial expressions
Prefrontal Cortex Area of cortex, w/reciprocal connections to Amygdala, involved in expressing, inhibiting & reading emotion
Phineas Gage Famous patient with damage to above area from accident during building railway
Theory of Mind Capacity to attribute mental states to others, prob. mediated by late-developing Prefrontal-Amygdala links
Helplessness Prefrontal assessment of negative situation one is powerless to affect, can lead to Parasym-rebound ulcers
Anterior Insula Vetral, medial area of above cortical region involved in facial expression and (taste) reaction of disgust
Emotional Facial Paresis Result of damage in above area involving deficit in ability to spontaneously smile
Volitional Facial Paresis Result of damage to Motor Cortex for facial region that involves in deficit in voluntarily showing teeth
Gambling Task Common task used in lab to assess risk aversion
Serotonin NT whose low turnover level (per metabolite 5-HIAA levels) assoc'd w/impulsiveness, aggression & depression
CCK Excitatory NT associated with enhanced Startle Reflex
GABA Inhibitory NT, admits Cl- inons into cells, whose agonists (Valium, Xanax) are used to combat anxiety
Law of Effect Rule of Conditioning: Event assoc'd with + (vs. -) reinforcement will (vs. not) be repeated
Classical Conditioning Developed association between stimuli, especially involving an unconditioned response
Operant Conditioning Developed association between stimulus and response
Hebbian Cell Assemblies Co-activated neural circuits presumably involved in learning and retrieval of associations
Long-Term Potentiation (LTP) Physical changes in cells involved in above, associated with learning
Hippocampus Area of brain in which above process has been well studied/described
Glutamate Type NT involved in above
AMPA Type of receptor site for above NT that is ionotropic and easy to stimulate
NMDA Type of receptor site for above NT that is difficult to stimulate, & often requires above to first hypo-polarize cell
Mg++ Type of ion that blocks ion gate of above receptor site
AMPA Type of receptor site that above can change into, after repeated co-activity in a circuit
Dendritic Branching One kind of change to dendrite structure that results in an increase in surface area and thus of available sites
Perforation Act by post-synaptic cell membrane that results in division of "active zone" of pre-synaptic terminal
Genetic changes DNA transcribed to RNS translated to Protein production that increases likelihood of neural activity
Neurogenesis Rare (except in Hippocampus) generation of new neurons associated with learning
Spatial Memory Recall of specific locations, spatial judgments of familiarity
Hippocampus Area of brain in which above process has been well studied/described
Procedural Memory Motor Skill, How to do it (peck a target, ride a bike)
Cerebellum & Striatum Areas of brain in which above process has been well studied/described
Declarative Memory Episodic (personal history) & Semantic/Associative (facts) memory
Hippo. & Mediodorsal Thal Areas of brain in which above process has been well studied/described
Place Cells Types of cells found in Hippocampus whose activity becomes associated with particular parts of a familiar env
Cognitive Map The type of map formed by a subject who gets to know the spatial layout of a particular environment
Lateral Imterpositus (LIP) Subsection of above hindbrain area associated with conditioning of "eye blink" response
Red Nucleus Area of Tegmentum (in midrain) that also plays a role in "eye blink" response
Match to Sample Task requiring application of rule "Pick alternative that is the same as the sample stimulus"
Hippocampus Area leasioned in rats caused impairment on above task
Mediodorsal Thalamus Area that projects to Prefrontal Cortex, implicated in declarative memory
Prefrontal Cortex Area of Cortex associated with "working memory", especially when response delays are involved
Korsakoff's Syndrome Syndrome, from B1 deficiency via chronic alcoholism, that esp affects cells of above area
Anterograde Amnesia Type of memory deficit most commonly associated with above
Confabulation Symptom of above involving "tale-telling" in which imagination not distinguished from knowledge
H.M. Famous patient with damage to Hippocampus & other temporal areas. Symptoms include…
Anterograde Amnesia Deficit in ability to generate new ("consolidate") memories
Declarative Memory Type of learning/memories above patient unable to form
Procedural Memory Above patient did NOT show deficits in this type of learning/memory
Amygdala Limbic structure that plays a role in learning such as "Conditioned Fear", and in arousal to "taboo"
Prosopagnosia Deficit in ability to recognize (remember) faces
Inferior Temporal Cortex Area of brain associated with above, where presumably relevant data are "stored"
Dorsal Temporal Cortex Area of brain where well-learned voices, words are "stored"
Lateralization Dominance of one cerebral hemisphere over the other for particular functions
Wada Test Test in which one hemisphere is anesthetized to test for capacity/speed of processing of other
Planum Temporale Area in left temporal cortex larger in most humans (& some other primates), assoc'd with language processing
Interference Cognitive principle that like-disrupts-like (e.g. left hemisphere activated by language>>slower rt hand response)
Corpus Callosum Main bundle of axons connecting two hemispheres
Split-Brain Patient Patient in whom above connections have been severed (as in treatment for Epilepsy)
Anterior Commisure Additional inter-hemisphere connection, between anterior cortex, esp of temporal lobes
Left Hemisphere Hemisphere dominant for most language processing
Broca's Area Area associated with language production
Frontal Cortex (Lateral Premotor) Location of this area
Broca's (or Productive) Aphasia Type of aphasia associated with damage to this area
Atriculation One type of difficulty in above, in which speech is slow and halting
Agrammatism Another deficit involving word order and the use of syntax markers
Closed Class Terms The fixed class of terms that organize syntactical relations such as prepositions, articles, conjunctions, etc.
Anomia Deficit involving difficulty in "finding" words, esp of the above class
Sign Language Production Deficit in one aspect of the "language of the deaf" associated with the above
Wernicke's Area Area associated with language comprehension
Temporal Cortex (Dorso-Posterior) Location of this area
Wernicke's (or Receptive) Aphasia Type of aphasia associated with damage to this area
Fluency Unlabored speech, with normal prosody, as seen in above
Anomia Deficit involving difficulty in "finding" words, esp of the class below
Content Terms Open (changeable) class of terms that includes nouns and verbs
Pure Word Deafness Deficit in which patient cannot understand spoken words at all (even if can read or write)
Nonsensical Speech Deficit involving using irrelevant or made-up words
Sign Language Comprehension Aspect of language of the deaf NOT affected by damage to the above area
Parietal Lobe Cortical area in which damage would result in affecting above language of the deaf
Arcuate Fasiculus Fibers that connect the above areas involved in production and comprehension of speech
Conduction Aphasia Type of aphasia associated with damage to this area
Phonemic Paraphasia Deficit in which similar sounding words, but with different meanings, are substituted during attempt to repeat
Phonological Loop Aspect of working memory involving rehearsal that is probably important normal function of these connections
Right Hemisphere The following are specializations of this hemisphere
Global Pattern Recognition Ability to get the "gist", to see the "larger picture", to organize narrative, etc.
Spatial Abilities Abilites involved in learning, remembering and navigating environments
Socio-Emotional Abilites involved in facial and nonverbal expression and interpretation
Music Domain in which above abilites come into play in the aesthetic organization of sound
Created by: willmichaelsen
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