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Cogs17 Course Review
Cogs17 Vocab
| Question | Answer |
|---|---|
| Connecting to the SAME side vs. connecting to the OPPOSITE side | Ipsilateral / Contralateral |
| Towards the sides vs. toward the middle | Lateral / Medial |
| Towards the stomach or the bottom of the human head vs. towards the back or the top of the human head | Ventral / Dorsal |
| A structure above another vs. one below another | Superior / Inferior |
| Planes through head as seen from the front vs. the side vs. above | Coronal / Saggital / Horizontal |
| Division of the Forebrain that ultimately becomes the Thalamus, Hypothalamus and the eye | Diencephalon |
| Division of the Forebrain that ultimately becomes the Cerebral Cortex, Basal Ganglia, Limbic System, etc. | Telencephaon |
| Hindbrain structure, controls vital reflexes | Medulla |
| Hindbrain structure, acts as bridge between Hindbrain and higher centers | Pons |
| Hindbrain structure, involved primarily with guided, timed movements | Cerebellum |
| Network of cells moving through hind- and mid-brain, involved in arousal | Reticular Formation |
| Core strip of cells through hind-and mid-brain, involved in sleep | Raphe System |
| Midbrain structure involved in motor processes | Tegmentum |
| Midbrain structure involved in sensory processes, includes Superior (visual) and Inferior (auditory) Colliculi | Tectum |
| Forebrain structure, oversees 4Fs, temperature, clock; communicates with and through the endrocrine system | Hypothalamus |
| Forebrain structure, "Master Gland", stimulated by Hypothalamus | Pituitary Gland |
| Forebrain structure, a principal stop along most sensory pathways | Thalamus |
| A set of forebrain structures involved in motivation and emotional expression | Limbic System |
| Forebrain structure, involved in the formation of new memories | Hippocampus |
| Forebrain structure, associated especially with anger and fear | Amygdala |
| Forebrain structure, layer mediating between cortex and lower systems, especially for socio-emotional evaluation | Cingulate Gyrus |
| Forebrain structure, receives smell info from olfactory receptors | Olfactory Bulb |
| Forebrain structure including Caudate Nucleus, Putamen & Globus Pallidus, involved in control of movement | Basal Ganglia |
| Forebrain structure including Nucleus Basalis, involved in arousal and attention | Basal Forebrain |
| Forebrain structure, outer "bark" of brain, 6-layered, highly convoluted | Cerebral Cortex |
| Set of axons connecting the two cerebral hemispheres | Corpus Callosum |
| Lobe of the cortex, posterior, primarily involved in visual processing, including V1 (Striate Cortex) | Occipital Lobe |
| Lobe of the cortex, lateral, primarily involved in auditory processing (e.g. A1 and Wernicke's) and higher visual (IT) | Temporal Lobe |
| Lobe of the cortex posterior to the Central Sulcus, primarily involved in somatosensory and visio-spatial maps | Parietal Lobe |
| Lobe of the cortex anterior to Central Sulcus, motor control including Broca's Area and, in Prefrontal Area,strategy & self control | Frontal Lobe |
| Part of the CNS other than the brain | Spinal Cord |
| Part of the Spinal Cord through which sensory info enters. vs. through which motor info exits | Dorsal Root / Ventral Root |
| "Law" governing above directions of information flow | Bell-Magendie Law |
| Area of the Spinal Cord (as seen in cross-section) consisting of soma vs. of myelinated axons | Grey / White Matter |
| Tube through core of Spinal Cord containing fluid | Central Canal |
| Four hollow chambers (plus aqueducts) in brain that produce the fluid that feeds, cleans and cushions brain | Ventricles |
| Fluid, produced by ventricles, found within Spinal Cord and in covering surrounding CNS | Cerebral Spinal Fluid (CSF) |
| Three-layered (Dura-, Fluid-filled Arachnoid- and Pia-Mater) protective covering that surrounds CNS | Meninges |
| Semi-permeable barrier, controls what chemicals enter brain, created by closing gaps between capillaries' endothelial cells | Blood Brain Barrier |
| That part of the PNS that is responsible for the body's interaction with the environment | Somatic Nervous System |
| That part of the PNS that is responsible for assessing and maintaining the body's internal environment | Autonomic Nervous System |
| That part of the ANS that produces the "fight or flight" response vs. that which facilitates relaxation and replenishment | Sympathetic / Parasympathetic NS |
| Extreme compensatory response of one system to extreme activation of the other - can lead to fainting, ulcers, voodoo death | Parasympathetic Rebound |
| Cells in the Nervous System responsible for information transmission | Neurons |
| Cells in the Nervous System responsible for support, feeding, recycling, development, etc | Glial cells |
| Organelles in a cell that are the site of protein production, crucial to much neural functioning | Ribosomes |
| Organelles in a cell that are the source of energy (ATP) to power active (vs. passive) funcitons in cell | Mitochondria |
| Processes (branches) of a neuron that receive the incoming message vs. the one that releases the outgoing message | Dendrites / Axon |
| Difference in the amount of a given chemical inside/outside a cell vs. a difference in charge inside/outside a cell | Concentration / Electical Gradient |
| Symbols for 4 key chemical elements in neural functioning - including 3 positive ions, 1 negative ion | Na+, K+, Ca++, Cl- |
| Name for and amount of difference in charge inside/outside cell, in millivolts (mV), in a polarized cell ready to fire | Resting Potential (-70mV) |
| Energy-requiring pump that helps restore membrane potential after cell fires | Sodium-Potassium Pump |
| A sequence of depolarization that moves along an axon, resulting in the all-or-nothing release of NT | Action Potential |
| Section of axon where depolarization sequence begins | Axon Hillock |
| A greater or lesser change in the polarity of a neuron that results in a greater or lesser release of NT | Graded Potential |
| Propagation of info down an axon by way of chemical gates opening/closing vs. by flow of electrons | Ionic / Electrical Conduction |
| "Jumping" electrical conduction that occurs in myelinated axons | Saltatory Conduction |
| Glia cells wrapping around sections of an axon to insulate it and speed its information transmission | Myelination |
| Gaps between myelin sheaths on an axon | Nodes of Ranvier |
| Disease that destroys myelin; no ion gates under sheath so neuron cannot fire | Multiple Sclerosis (MS) |
| Period following an Action Potential during which the cell cannot (or is more difficult to) fire | Refractory Period |
| The event in which one cell releases NT and that NT affects another cell | Synapse |
| The gap between cells across which NT passively floats | Synaptic Cleft |
| The cell that releases the NT vs. the cell that receives the NT | Pre- / Post Synaptic Cell |
| The end of the axon from which NT is released, also called "button" or "end bulb" | Pre-Synaptic Terminal |
| Packets of NT released by a neuron | Vesicles |
| The release of NT into cleft via its packet opening at a Fusion Pore in the cell's membrane | Exocytosis |
| Area, usually on a dendrite, that is specialized for the attachment of NT | Receptor Site |
| An increase vs. a decrease in a cell's likelihood of releasing neurotransmitter | EPSP / IPSP |
| Less polarized, less difference between inside of cell and outside of cell vs. more difference | Hyper / Hypo-Polarization |
| Cumulative effect of the activity of multiple Presynaptic cells; Can be temporal or spatial | Summation |
| When NT has direct effect on ion channels in Postsynaptic cell vs. indirect effects via internal metabolic processes | Ionotropic / Metabotropic |
| Chemical in Postsynaptic cell involved in energy-requiring processes (including altering ion channels) triggered by NT | Second Messenger |
| Chemicals released by Presynaptic cells that directly affect local Postsynaptic cells vs. ones that widely influence neural activity | Neuro-transmitters / -modulators |
| Chemical (endogenous or man-made) that acts to facilitate (via imitation or enhancement) vs. to block the effects of specific NTs | Agonist / Antagonist |
| Process by which NTs or their components re-enter the Presynaptic cell for re-use. | Reuptake |
| Enzyme in cleft that breaks down Acetylcholine | Acetylcholinesterase |
| Site on Presynaptic terminal that reacts to that cell's own NT, usually acting to turn off/down that cell's further NT release | Auto-Receptors |
| Synapses at Presynaptic terminal that reacts to NT from other cell, excitatory or inhibitory | Axoaxonic Synapses |
| Epinepherine (Adrenalin), Testosterone, Estrogen, Oxytocin, Insulin, Cortisol | 6 Hormones |
| Acetylcholine | ACh Acetylcholine |
| Dopamine | DA Dopamine |
| Serotonin | 5-HT Serotonin |
| Norepinepherin | NE Norepinepherin |
| Adrenalin | Epinepherine |
| Glutamate | Glutamate |
| GABA | GABA |
| Substance P | Substance P |
| Endorphins | Endorphins |
| In the new embryo, the outermost layer of cells - becomes the nervous system and skin | Ectoderm |
| In the growing (wormlike) embryo, the surface along the back that thickens and hardens | Neural Plate |
| A pair of ridges all along the above that begin to curl towards each other | Neural Folds |
| The long hollow chamber that is formed when the above meet and fuse, inner surface becomes the CNS | Neural Tube |
| Outer surface of the above ridges that separate off and become the PNS | Neural Crest |
| A pathological condition involving a failure of the edges above to completely fuse, leading to birth defects or death | Spina Bifida |
| The original type of cells in this area that undergo division to populate nervous system | Stem Cells |
| Cell division that produces two identical offspring vs. produces one identical and one new (neuron or glial) cell | Symmetrical / Asymmetrical Division |
| An early type of glial cell that extends its processes out like wheel spokes for the developing neurons to migrate along | Radial Glia |
| Glia cells that are positioned to direct growing axons towards their target cells | Guidepost cells |
| Cell Death as determined by "suicide genes" that cause developing neurons to package their contents & destroy themselves | Apotosis |
| Chemicals that attract/repel Axon growth, help prevent cell death, and/or promote Axonal branching | Neurotrophins |
| One type of the above, from muscles & organs, that promotes survival and growth of axons in the brain and Sympathetic NS | Nerve Growth Factor (NGF) |
| Newly formed axonal branch that replaces another (that has died off) at a synapse | Collateral sprout |
| New outgrowths on, or subdividing of, the processes that receive NT, in response to an enriched enviornment, learning, etc. | Dendritic spines / branching |
| The production of new cells | Proliferation |
| The movement of cells from their place of origin to their later position | Migration |
| The formation of new synapses | Synaptogenesis |
| A mnemonic for the rule that co-activated cells tend to be strengthened in their connectivity and out-compete neighboring cells | Fire together > Wire together |
| The production of new cells | Proliferation |
| The movement of cells from their place of origin to their later position | Migration |
| The formation of new synapses | Synaptogenesis |
| A mnemonic for the rule that co-activated cells tend to be strengthened in their connectivity and out-compete neighboring cells | Fire together > Wire together |
| Convergence (or Summation) | When multiple pre-synaptic cells all communicate to one post-synaptic cell |
| Divergence | When one presynaptic cell communicates to many post-synaptic cells |
| Receptive Field | Set of receptors whose actitvity influences the activity of target cell |
| Excitatory Center- Inhibitory Surround | Type of above: stimulating center increases target response, non-center decreases it |
| Topological | Type of map that preserves spatial relaitonships (as along a sensory surface) |
| Magnification | In cortex, disproportionate enlargement of the rep. of a sensory area of low convergence |
| Module | An area of the brain specialized for processing one particular type of information |
| The Binding Problem | The problem posed by having several of the above, and yet perceiving wholes |
| Retina | Rear layers of neurons in the eyeball |
| Receptors (Rods & Cones) | Cells that respond to light; show spontaneous, graded release of inhibitory NT |
| Rods | Above that are convergent, sensitive to motion & low light, mainly in periphery |
| Cones | Above that connect few:1, sensitive to color & detail, dispersed plus conc'd in center |
| Fovea | Central area of above receptor types only, connected 1:1 for highest acuity |
| Bipolars | Next cell in pathway, spontaneous, graded potentials, release excitatory NT |
| Horizontals | Inter-neurons that modify reaction of above, implicated in color opponency |
| Ganglions | Next cell in pathway, action potentials, release excitatory NT |
| Optic Nerve | Formed of axons of the above |
| Optic Disc | Place where above leaves eye for brain, also called "Blind Spot" |
| Amacrines | Inter-neurons that modify reaction of above, implicated in contrast effects |
| Dim | Level of light (bright vs. dim?) that results in greatest release of NT from receptors |
| Bright | Level of light (bright vs. dim?) that results in greatest release of NT from bipolars |
| Acuity | High-detail discrimination, as from low convergence, that retains info on diffs |
| Sensitivity | High likelihood of detection, as from high convergence that crosses next cell's threshold |
| Lateral Inhibition | Cell activity resulting in release of inhibitory NT to cells orthogonal to info pathway |
| Simultaneous Contrast | Illusion created by above that alters perception of central grey depending on its surround |
| Uni-directional | Direction of inhibition (uni- or bi-directional?) in direction-senstive motion circuit |
| Lateral Geniculate Nuc or LGN | Nucleus in Thalamus that processes most visual information from eye |
| Column | In cortex, set of cells, in 6 layers, that all respond to the same preferred stimulus |
| Hyper-Column | In cortex, set of cells that all have same RF and include set of orientation cols & blobs |
| Retinotopic Map | Topological map that preserves spatial relationships found on Retina |
| A1 or Striate Cortex | Primary Projection area for vision in Occipital Lobe of cortex |
| Parvocellular Pathway | Visual pathway specialized for color and detail, that "flows" along bottom of cortex |
| Temporal Pathway | Above also called...because it terminates in this lobe of the cortex |
| What/Who Pathway | Above also called…because it conveys info that helps you to identify a stimulus or individual |
| Parvocellular or X Ganglions | Small ganglion cells that begin this pathway, with small RFs & sustained response |
| Magnocellular Pathway | Visual pathway specialized for motion and localization,"flows" along top part of cortex |
| Parietal Pathway | Above also called …because it terminates in this lobe of the cortex |
| Where/How Pathway | Above also called…because it conveys info that helps locate & interact w/stimuli |
| Magnocellular or Y Ganglions | Large ganglion cells that begin this pathway, with large RFs & transient response |
| Superior Colliculus | Nucleus in Midbrain in this path, processes some visual (esp motion) info from eye |
| Blindsight | Tho vis cortex damaged & no visual experience, midbrain enables some vis localization |
| Trichromatic Color Vision | Color coding per ratio of activity of 3 cone types reponding to 3 overlapping ranges of freqs |
| Color Opponency | Recoding of above, via lateral inhibition from Horizontal cells, into Red/Green & Blue/Yellow |
| Opponent Cells | LGN or Ganglions with R+G-, G+R-, B+Y- or Y+B- receptive fields |
| Color Constancy | V4-mediated process that enables ID of color under diff light conditions (AKA "Retinex Theo") |
| Simple Cells | Cells in V1 that respond to line, or gradient, oriented in particular direction |
| Complex Cells | Cells in V2 that give best response to moving lines of particular orientation |
| Spatial Frequencies | Number of dark/light changes per degree of visual angle |
| High Frequency | Frequency gradients (high vs. low?) that V1 cells in Parvo path are most sensitive to |
| Low Frequency | Frequency gradients (high vs. low?) that V1 cells in Magno path are most sensitive to |
| Inferior Temporal or IT | End of Parvo pathway, includes cells that prefer hand, face, other complex stim |
| Prosopagnosia | Deficit from damage to Fusiform Gyrus, patient cannot recognize familiar faces |
| MT | Cortex with direction-sensitive cells, responds best to stimulus moving across retina |
| MST | Cort4x with optic-flow detectors that repond best to contraction/expansion of whole scene |
| Disparity Detectors | In V2 or MT, cells that respond to degrees of diff between location of an image on 2 retina |
| Tympanic Membrane | Membrane vibrated by air molecules moving down Auditory Canal |
| Ossicles | Three tiny bones linked into lever system, amplify vibrations of above |
| Oval Window | Membrane vibrated by third bone above, initiating vibration of… |
| Cochlear Fluid | Thick, incompressible, potassium-rich fluid that fills… |
| Cochlea | Coiled, three-chambered tube in Inner Ear which contains… |
| Organ of Corti | Section of central chamber where Receptor Cells are found |
| Basilar Mambrane | Membrane that runs along floor of above structure, moves up and down |
| Tectorial Membrane | Membrane that runs along roof of above structure, moves forward & back |
| Hair Cells | Auditory receptor cells that are deformed between the above two membranes |
| Cillia | Tiny "hairs" extending from above cells whose deformation initiates transduction |
| K+ | Ion that enters receptor, descreasing its polarity |
| Ca++ | Ion that enters receptor, causing chain reaction that results in release of NT |
| Glutamate | NT released by auditory receptors |
| Graded Potential | Type of change in polarity in receptors (graded vs. action potential?) |
| Spiral Ganglions or ANFs | Cells to which Receptors communicate, whose axons exit to brain |
| Action Potential | Type of change in polarity in these cells (graded vs. action potential?) |
| Place Coding | Relative levels of activity across differentially-resonating Bas. Memb. code freq |
| Temporal Coding | Rate of oscillation of Bas. Membrane codes freq per rate of Auditory Nerve Firing |
| Refractory Period | Time during which Auditory Nerve Fibers cannot fire next Action Potential |
| Volley Principle | Since each above can only fire 1/1000sec, must work together at alt. intervals |
| Phase Locked | Ganglions involved in above can all only fire at the same phase (e.g.) peak of input wave. |
| Amplitude Differences | Diffs used for localization, caused by "head shadow" attenuating high freqs |
| Phase Differences | Diffs used for localization, comparing peak & trough of lower frequencies |
| Timing Differences | Diffs used for localization, per race of left vs. right Onset signals to Superior Olive |
| Inner Hair Cells | Receptor Cells that show divergent connectivity, for detail freq discrimination |
| Outer Hair Cells | Receptor Cells that show convergent connectivity, for loudness discrimination |
| Auditory Nerve | Axons of next cells in path form this nerve |
| 8th Cranial Nerve | Above is part of (?) Cranial Nerve |
| Cochlear Nucleus | Next synapse in Medulla, beginning of separate information pathways |
| Primary Like Cell | Cell in above nucleus that duplicates the incoming signal |
| Tonotopic Map | Above helps generate what kind of map that reps low>high frequency across cell array |
| Onset Cell | Cell in above nucleus that transforms incoming signal into a transient burst |
| Build Up Cell | Cell in above that transforms incoming signal into one of graded, increasing amp |
| Monaural | When information from only one ear is involved, as in the above |
| Binaural | When info from both ears is combined, good for localization, as in the following… |
| Superior Olive | Next auditory site, also in Medulla, responsible for Orienting Reflex |
| Inferior Colliculus | Next auditory site, in Midbrain, where info integrated with visual at nearby site |
| Medial Geniculate Nuc or MGN | Next auditory site, in Thalamus, site of among other things… |
| A1 | Primary Projection Area for audition, in Temporal Lobe of cortex |
| A2 | Secondary Auditory area in cortex |
| Wernicke's Area | Area with critical role in the comprehension of speech, in left hemisphere |
| Music | Type of complex auditory input processed by higher auditory centers in right hemi. |
| Hair Cells | Type of receptor cells in Vestibular system |
| K+ | Ion, when not/allowed to enter cell, changes receptor's polarity |
| Spontaneous Firing Rate | Changes in velocity & orientation alter this kind of firing rate |
| Otolith Organ | Where receptors respond to head tilt via gravity-induced deformation by crystals |
| Semi-Circular Canals | Three fluid-filled tubes that detect changes in angular acceleration |
| Motion Sickness | Effect when visual and/or motor feedback is inconsistent with vestibular info |
| 8th Cranial Nerve | Cranial nerve (?) shared with audition |
| Free Nerve Endings | Class of receptors that respond to temp, pain, itch and hair follicle movement |
| Nociceptors | Receptors in above class that respond to "noxious" (potentially damaging) stimuli |
| Encapsulated Endings | Class of receptors that respond to touch and internal movement |
| Proprioception | Detection of internal movement of muscles and organs |
| Action Potentials | Type of response by above type of receptors (graded or action potentials?) |
| Selective Adaptation | Process by which one type of receptor is fatigued, showing its role in coding |
| Ventral Posterior Nuc or VPN | Nucleus of Thalamus in somatosensory pathway |
| Spinal Thalamic Pathway | Path for pain and temperature info to brain, crossing over in Spinal Cord |
| Medial Lemniscal Pathway | Path for touch and internal motion info to brain, crossing over in Brainstem |
| MLP | Which of above paths tends to be myelinated |
| Brown-Sequard Sndrome | When damage to one side of spine results in diff losses on ipsi- vs. contra-lateral sides |
| Post-Central Gyrus | Location of Primary Projection Area (S1) for somatosensory info |
| Penfield Map | Name of topological map of body surface found there |
| Hands and Mouth | Parts of body that fill disproportionate areas of this map |
| Substance P | Neurotransmitter released by pain receptors and other cells in pain pathway |
| Gate Theory | Theory concerning the top-down blocking of pain info entering brain |
| Peri-Aquaductal Grey or PAG | Midbrain area that is probably the source of this blocking |
| Endorphins | "Endogenous morphines" released by above |
| Inhibitory Interneuron (SG) | Type of inter-neuron in spine that responds to above input |
| Naloxone | Opiate antagonist that reduces analgesic effects of morphine & acupuncture |
| Striate Muscles | Type of muscle, made of parallel fibes, attached by tendons to bones |
| Flexors | One type of above, that moves bone toward body, in antagonistic pair with… |
| Extensors | …other type, that moves bone away from body |
| Neuro-Muscular Junction | Where neuron releases NT that depolarizes muscle fiber cells > contraction |
| Acetylcholine ACh | Neurotransmitter released by effector neurons to contract muscles |
| Sarcomere | The contractile unit of a muscle fiber, consisting of… |
| Myosin | Thick protein filament with knobby bead-like Cross Bridges along it, and… |
| Actin | Thin braided protein filament, anchored to muscle, that above hook into & tighten |
| Spindle | A proprioceptor that detects passive stretch of a muscle, triggering… |
| Stretch Reflex | A mono-synaptic reflex that contracts muscle to counter passive stretch |
| Golgi Reflex | A reflex triggered by Tendon Organs detecting excessive contraction in muscle |
| Pain Withdrawal Reflex | A reflex triggered by pain detectors, rapidly removing skin from source of pain |
| Scratch Reflex | A reflex involving an Oscillator Circuit producing a fixed-rate rhythm |
| Infant Reflexes | Reflexes, such as "rooting" or "grasping", found in newborns |
| Primary Motor Cortex | Area of cortex that includes body map, sends movement commands to Stem and Cord |
| Pre-Central Gyrus | Location of above |
| Premotor Cortex | Anterior to above, active during preparation to move, receives esp from Visua-Spatial areas |
| Mirror Cells | Above includes cells that respond to image of self, or other, performing familiar manual task |
| Broca's Area | Lateral area that plans articulation, helps generate gramatical sentences (esp in left hemi) |
| Supplementary Motor Cortex | Dorsal to above, also active during prep, esp for rapid moves, receives from Parietal |
| Cortico-Spinal Pathway | Fast, crossing paths from Pyramids in cortex, esp. for precise control of peripheral moves |
| Red Nucleus (of Tegmentum) | Above stops at this Midbrain structure on way from Cortex to Medulla & Cord |
| Ventro-Medial Pathway | Mainly ipsilateral pathways for posture & gross movement of neck, shoulders & trunk |
| Cerebellum | "Little brain" involved esp in coordinated movement requiring aiming and timing |
| Ballistic | Movements that occur very rapidly & generally cannot be altered once begun |
| Purkinje Cells | "Telephone poles" in cerebellar cortex that help code time as distance |
| Parallel Fibers | "Wires" in above whose action potentials release excitatory NT |
| Deep Nuclei | Central areas that receive from "telephone poles" and send output to Brain/Cord |
| Basal Ganglia | Set of forebrain structures controlling posture, muscle tone, & smooth movement |
| Parkinson's Disease | Movement impairment, marked by rigidity, tremors etc, from degeneration of… |
| Substantia Nigra | Midbrain structure whose dopaminergic axons synapse in Basal Ganglia |
| L-Dopa | Precursor of dopamine, crosses barrier, converted by neurons into dopamine |
| Beta Activity | EEG while awake/active, 18-24 Hz, Very high freq, very desynchronized |
| Alpha Activity | EEG while awake/relaxed, 8-12 Hz, Like above, somewhat more sync’d |
| Theta Activity | EEG during Sleep I, 4-7 Hz, Lower freq, still quite irregular, more sync'd |
| Delta Activity | EEG during Sleep 3(&4), <4 Hz in less (&more) than 50% , Very low freq, very high voltage, very sync’d |
| Spindle and K Complex | During Sleep 2, 2 types of intermittent bursts of high freq or voltage, as brain settles into deeper sleep |
| Slow Wave Sleep | Another term for Sleep 3 & 4, re: its low frequency EEG and highly synchronized activity |
| REM (Rapid Eye Movement) | Stage of Sleep associated with dreams |
| Paradoxical Sleep | Another name for above due to its contradictory nature (active, desynch'd brain, but paralyzed body) |
| Atonia | Condition in which Pons suppresses motor signals sent to Cord, so muscle action prohibited |
| PGO Wave | Sequence of activation in Pons => (Lateral) Geniculate => Occipital Cortex that initiates dream sleep |
| ACh | Excitatory neurotransmitter released by above to desychronize brain |
| 90 Minutes | Duration ( minutes) of one sleep cycle through Stages 1, 2, 3, 4, 3, 2, “Dream” sleep |
| REM Rebound | Condition after sleep deprivation in which system attempts to enter “Dream” sleep more frequently |
| Suprachiasmatic Nuc (SCN) | Location in Hypothalamus of Circadian Clock |
| Zeitgeber | “Time Giver”, a stimulus, such a bright sunlight, that can reset Circadian Clock |
| Retino-Hypothalamic Path | Path of Optic Nerve collateral that connects special visual receptors in eye directly to clock |
| Pineal Gland | Gland that produces a hormone that impacts on Hypothalamus to increase sleepiness |
| Melatonin | The hormone mentioned above, which can also be taken as a sleep aid. |
| Basal Forebrain | Forebrain structure (anterior & dorsal to Hypothal) that modifies arousal in cortex |
| ACh | Neurotransmitter released by above that increases cortical arousal |
| GABA | Neurotransmitter released by above that decreases cortical arousal |
| Adenosine | Chemical that builds up in cells, released as NT, inhibits release of above excitatory NT, promotes sleep |
| Caffeine | Stimulant that blocks receptors for above, allowing continued cortical arousal |
| PreOptic Area | Nucleus of Hypothalamus critical in initiating sleep (also assesses & regulates body temperature) |
| Raphe Nuclei | Structure in Pons whose functions include shutting off REM sleep |
| Serotonin (5HT) | Neurotransmitter released by above nuclei; very low in Slow Wave Sleep, very high at the end of REM |
| Reticular Formation | “Net” from Medulla & Pons, for widespread arousal of Forebrain, esp Thalamus and Basal Forebrain |
| ACh and Glutamate | Two neurotransmitters released by above, to alert brain |
| Locus Coeruleus | (“Dark Blue Place”) An arousal center, active during new tasks , vigilance, memory formation |
| Norepinepherine (NE) | Neurotransmitter released by above, absent during dreams; Amphetamines are antagonists for this NT |
| Organizing vs. Activating | Effects of reproductive hormones on anatomy vs. on behavior |
| Estrogens vs. Androgens | Class of reproductive hormones found in greater proportion in Females vs. in Males |
| XX vs. XY | Sex chromosomes typical of Females vs. Males, which help determine gender |
| Wolffian vs. Muellerian | Systems of ducts in fetus that become part of internal reproductive organs of Males vs. Females |
| Testosterone | A Male hormone, produced by testes, responsible for development of Male anatomy and behavior |
| Anti-Muellerian Hormone | Another Male hormone that inhibits development of Female system of internal ducts |
| Testis-Determining Factor (TDF) | Enzyme produced by “switch” on Male chromosome that leads to the development of gender |
| Androgen-Insensitivity | Condition in which genetic-male fetus does not respond to Male hormones and thus develops as Female |
| Turner’s Syndrome | Condition in which fetus lacks Y Chromosome, develops internally & externally as infertile Female |
| Estradiol | A Female hormone, (similar to Testosterone) that, once inside fetal cells, promotes Male development |
| Apha-Fetoprotein | Chemical in fetal bood that prevents mother’s hormones from entering fetal cells and masculinizing fetus |
| Medial Preoptic Area (MPOA) | Area of Hypothalamus w/receptor sites for Male hormones, esp active during Male sexual behavior |
| Sexually Dimorphic Nuc (SDN) | Above includes this nucleus which is 2.5X larger in Males than Females |
| INAH3 | Part of above nucleus that is smaller in both Females and Homosexual Males |
| Ventro-Medial H. (VMH), | Area of Hypothalamus w/receptor sites for Female hormones, esp active during Female sexual behavior |
| Corpus Callosum | Fibers connecting cortical hemispheres which is thicker in Females, who are thus less-lateralized |
| Gonadotropin-Releasing (GnRH) | Hormones released by Hypothalamus causing Anterior Pituitary to release its reproductive hormones |
| LH and FSH | Two Gonadotropic hormones that stimulate development and behavior in both genders |
| Androstenedione | Male hormone released by Female Adrenal Glands, stimulates secondary hair growth & sexual behavior |
| Nucleus Accumbens | Area near Basal Forebrain associated with the sensation of sexual pleasure |
| Dopamine | Neurotransmitter released by above area in response to sexual stimulation |
| Oxytocin | Hormone released by Posterior Pituitary at time of orgasm |
| Prolactin | Hormone released by Anterior Pituitary for refractory period in Males and milk production in Females |
| Periaqueductal Gray Area | Part of Tegmentum active especially in Females during sex |
| Endorphins | Neurotransmitter released by above area, including to supress potential for pain |
| James-Lange Theory | Theory that suggests emotion is an after-the-fact label we give to arousal and assoc'd behavior |
| Cannon-Bard Theory | Theory: Once threat perceived (via Thalamus), emotion is simultaneous ANS activity & subjective experience |
| Papez Circuit | Update of above that includes Limbic Syustem in circuit |
| Schater-Singer Theory | Theory: Emotion is interaction between cognitive appraisal and autonomic/limbic activity |
| Amygdala | Key Limbic structure implicated in interpreting valenced situations and coordinating an emotional response |
| Corticomdial Area | Area of above, when stimulated, promotes attack |
| Lateral Nuclei | Area of above responsible for coordinating Startle Reflex |
| Central & Basolateral Nuclei | Areas of above involved in Coniditioned Fear and subsequent enhancement of Startle Reflex |
| Urbach-Weith Disease | Degenerative calcium buildup in Amygdala that results in deficits in interpreting facial expressions |
| Prefrontal Cortex | Area of cortex, w/reciprocal connections to Amygdala, involved in expressing, inhibiting & reading emotion |
| Phineas Gage | Famous patient with damage to above area from accident during building railway |
| Theory of Mind | Capacity to attribute mental states to others, prob. mediated by late-developing Prefrontal-Amygdala links |
| Helplessness | Prefrontal assessment of negative situation one is powerless to affect, can lead to Parasym-rebound ulcers |
| Anterior Insula | Vetral, medial area of above cortical region involved in facial expression and (taste) reaction of disgust |
| Emotional Facial Paresis | Result of damage in above area involving deficit in ability to spontaneously smile |
| Volitional Facial Paresis | Result of damage to Motor Cortex for facial region that involves in deficit in voluntarily showing teeth |
| Gambling Task | Common task used in lab to assess risk aversion |
| Serotonin | NT whose low turnover level (per metabolite 5-HIAA levels) assoc'd w/impulsiveness, aggression & depression |
| CCK | Excitatory NT associated with enhanced Startle Reflex |
| GABA | Inhibitory NT, admits Cl- inons into cells, whose agonists (Valium, Xanax) are used to combat anxiety |
| Law of Effect | Rule of Conditioning: Event assoc'd with + (vs. -) reinforcement will (vs. not) be repeated |
| Classical Conditioning | Developed association between stimuli, especially involving an unconditioned response |
| Operant Conditioning | Developed association between stimulus and response |
| Hebbian Cell Assemblies | Co-activated neural circuits presumably involved in learning and retrieval of associations |
| Long-Term Potentiation (LTP) | Physical changes in cells involved in above, associated with learning |
| Hippocampus | Area of brain in which above process has been well studied/described |
| Glutamate | Type NT involved in above |
| AMPA | Type of receptor site for above NT that is ionotropic and easy to stimulate |
| NMDA | Type of receptor site for above NT that is difficult to stimulate, & often requires above to first hypo-polarize cell |
| Mg++ | Type of ion that blocks ion gate of above receptor site |
| AMPA | Type of receptor site that above can change into, after repeated co-activity in a circuit |
| Dendritic Branching | One kind of change to dendrite structure that results in an increase in surface area and thus of available sites |
| Perforation | Act by post-synaptic cell membrane that results in division of "active zone" of pre-synaptic terminal |
| Genetic changes | DNA transcribed to RNS translated to Protein production that increases likelihood of neural activity |
| Neurogenesis | Rare (except in Hippocampus) generation of new neurons associated with learning |
| Spatial Memory | Recall of specific locations, spatial judgments of familiarity |
| Hippocampus | Area of brain in which above process has been well studied/described |
| Procedural Memory | Motor Skill, How to do it (peck a target, ride a bike) |
| Cerebellum & Striatum | Areas of brain in which above process has been well studied/described |
| Declarative Memory | Episodic (personal history) & Semantic/Associative (facts) memory |
| Hippo. & Mediodorsal Thal | Areas of brain in which above process has been well studied/described |
| Place Cells | Types of cells found in Hippocampus whose activity becomes associated with particular parts of a familiar env |
| Cognitive Map | The type of map formed by a subject who gets to know the spatial layout of a particular environment |
| Lateral Imterpositus (LIP) | Subsection of above hindbrain area associated with conditioning of "eye blink" response |
| Red Nucleus | Area of Tegmentum (in midrain) that also plays a role in "eye blink" response |
| Match to Sample | Task requiring application of rule "Pick alternative that is the same as the sample stimulus" |
| Hippocampus | Area leasioned in rats caused impairment on above task |
| Mediodorsal Thalamus | Area that projects to Prefrontal Cortex, implicated in declarative memory |
| Prefrontal Cortex | Area of Cortex associated with "working memory", especially when response delays are involved |
| Korsakoff's Syndrome | Syndrome, from B1 deficiency via chronic alcoholism, that esp affects cells of above area |
| Anterograde Amnesia | Type of memory deficit most commonly associated with above |
| Confabulation | Symptom of above involving "tale-telling" in which imagination not distinguished from knowledge |
| H.M. | Famous patient with damage to Hippocampus & other temporal areas. Symptoms include… |
| Anterograde Amnesia | Deficit in ability to generate new ("consolidate") memories |
| Declarative Memory | Type of learning/memories above patient unable to form |
| Procedural Memory | Above patient did NOT show deficits in this type of learning/memory |
| Amygdala | Limbic structure that plays a role in learning such as "Conditioned Fear", and in arousal to "taboo" |
| Prosopagnosia | Deficit in ability to recognize (remember) faces |
| Inferior Temporal Cortex | Area of brain associated with above, where presumably relevant data are "stored" |
| Dorsal Temporal Cortex | Area of brain where well-learned voices, words are "stored" |
| Lateralization | Dominance of one cerebral hemisphere over the other for particular functions |
| Wada Test | Test in which one hemisphere is anesthetized to test for capacity/speed of processing of other |
| Planum Temporale | Area in left temporal cortex larger in most humans (& some other primates), assoc'd with language processing |
| Interference | Cognitive principle that like-disrupts-like (e.g. left hemisphere activated by language>>slower rt hand response) |
| Corpus Callosum | Main bundle of axons connecting two hemispheres |
| Split-Brain Patient | Patient in whom above connections have been severed (as in treatment for Epilepsy) |
| Anterior Commisure | Additional inter-hemisphere connection, between anterior cortex, esp of temporal lobes |
| Left Hemisphere | Hemisphere dominant for most language processing |
| Broca's Area | Area associated with language production |
| Frontal Cortex (Lateral Premotor) | Location of this area |
| Broca's (or Productive) Aphasia | Type of aphasia associated with damage to this area |
| Atriculation | One type of difficulty in above, in which speech is slow and halting |
| Agrammatism | Another deficit involving word order and the use of syntax markers |
| Closed Class Terms | The fixed class of terms that organize syntactical relations such as prepositions, articles, conjunctions, etc. |
| Anomia | Deficit involving difficulty in "finding" words, esp of the above class |
| Sign Language Production | Deficit in one aspect of the "language of the deaf" associated with the above |
| Wernicke's Area | Area associated with language comprehension |
| Temporal Cortex (Dorso-Posterior) | Location of this area |
| Wernicke's (or Receptive) Aphasia | Type of aphasia associated with damage to this area |
| Fluency | Unlabored speech, with normal prosody, as seen in above |
| Anomia | Deficit involving difficulty in "finding" words, esp of the class below |
| Content Terms | Open (changeable) class of terms that includes nouns and verbs |
| Pure Word Deafness | Deficit in which patient cannot understand spoken words at all (even if can read or write) |
| Nonsensical Speech | Deficit involving using irrelevant or made-up words |
| Sign Language Comprehension | Aspect of language of the deaf NOT affected by damage to the above area |
| Parietal Lobe | Cortical area in which damage would result in affecting above language of the deaf |
| Arcuate Fasiculus | Fibers that connect the above areas involved in production and comprehension of speech |
| Conduction Aphasia | Type of aphasia associated with damage to this area |
| Phonemic Paraphasia | Deficit in which similar sounding words, but with different meanings, are substituted during attempt to repeat |
| Phonological Loop | Aspect of working memory involving rehearsal that is probably important normal function of these connections |
| Right Hemisphere | The following are specializations of this hemisphere |
| Global Pattern Recognition | Ability to get the "gist", to see the "larger picture", to organize narrative, etc. |
| Spatial Abilities | Abilites involved in learning, remembering and navigating environments |
| Socio-Emotional | Abilites involved in facial and nonverbal expression and interpretation |
| Music | Domain in which above abilites come into play in the aesthetic organization of sound |