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Medications
Meds for complications of pregnancy
| Question | Answer |
|---|---|
| Terbutaline (aka Brethine) | Beta adrenergic used for pre term labor |
| Terbutaline is administered how? | Oral IV Sub Q injection |
| Side effects of Terbutaline | Nervousness restlessness insomnia headache tachycardia Nausea hyperglycemia |
| Rare but serious side effect of Terbutaline | Pulmonary edema |
| Fetal effects of Terbutaline | tachycardia |
| What med can reverse severe adverse effects? | Propranolol |
| Nursing care for Terbutaline | Assess: apical HR and lung sounds before administering fetal HR Notify doc if maternal HR >120 , fetal HR >160bpm or wet lung sounds |
| Magnesium sulfate | Decreases frequency and duration of contractions |
| Magnesium sulfate is administered how? | IV loading dose 4-6gms Maintenance dose 1-4 g/hr to stop ctx |
| Magnesium sulfate protocol | presence of DTR (knee jerk) Urine output of at least 30ml/hr Respirations at least 12/ min |
| Maternal Side effects of Magnesium sulfate | extreme warmth perspiration flushing N/V blurred vision lightheadedness lethargy constipation muscle weakness |
| Maternal Severe side effects of Magnesium sulfate | Chest pain SOB fluid build up in lungs low B/P and fast pulse |
| Fetal side effects of Magnesium sulfate | Decreased variability of FHR Lethargic and may experience difficulty breathing after birth Infants of moms treated w/ drug more often admitted to ICN |
| Nursing management of Magnesium sulfate | follow protocol: DTR's (knee jerk) output RR monitor heart and lung sounds serum magnesium levels FHR monitoring Calcium gluconate antidote Monitor I&O b/c it is excreted by kidney |
| Nifedipine | Prevents preterm ctx Does not stop labor if it is truly labor |
| Nifedipine is administered how? | orally |
| How does Nifedipine work? | blocks passage calcium into tissues, relaxing uterine muscles and blood vessels throughout body |
| Side effects of Nifedipine | dizziness, lightheadedness, skin flushin/ redness, headache, nausea, muscle cramps or tremors, hypotension |
| Nursing Implications for Nifedipine | Check B/P report pulse >110 DO NOT USE WITH MAGNESIUM SULFATE Monitor for fetal effects: fetal bradycardia, transient fetal tachycardia |
| Antibiotics | Used for infection both systemic and local strong association w/ PTL and PROM Lab work (cultures may take 24-48 hours) Amniocentesis for chorioamnionitis |
| Broad spectrum antibiotics used | Ampicillin or Penicillin Erythromycin or Clindamycin Metronidazole |
| Ampicillin or Penicillin dosage | 2Gm IV q 6 hrs x 2 days then 250mg po q8 hrs x 1 day |
| Erythromycin or Clindamycin | 250mg IV q6 hrs x 2 days then 333 mg po 8hrs x 1 day |
| Corticosteroids | ACOG recommended for infants delivering prior to 34 wks Given to speed lung maturation if <34 wks Delay birth for 24 hrs to give benefit |
| Teaching for Corticosteroids | teach patient signs of pulmonary edema |
| Corticosteroids Dose and Route | Betamethasone: 12mg 2 doses IM (mom) 24 hrs apart Dexamethasone: 6 mg 4 doses IM (mom) 12 hrs apart |
| Progesterone | Give to those who are high risk for preterm delivery and have prior hx of PTB It is Preventative, not treatment once PTL has started |
| Progesterone Dose and Route | Given IM q week beginning around 16-20 weeks and continuing through 36 wks |