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NUR 370 Unit 2 Drugs
NUR 370 Unit 2 Prototype Drugs
| Question | Answer |
|---|---|
| sulfamethoxazole-trimethoprim, sulfisoxazole-erythromycin | Sulfonamide prototypes |
| penicillin V potassium, penicillin G potassium, amoxicillin | Penicillin prototypes |
| cefazolin, cephalexin, keflex, cefoxitin, cefuroxime, ceftriaxone, cefepime | Cephalosporin prototypes |
| imipenm-cilastatin | Carbapenem prototypes |
| aztreonam | Monobactam prototypes |
| doxycycline, aoxycycline | Tetracycline prototypes |
| erythromycin, azithromycin, clarithromycin | Macrolide prototypes |
| gentamicin | Aminoglycoside prototypes |
| ciprofloxacin | Fluoroquinolone prototypes |
| telithromycin | Ketolide prototypes |
| clindamycin, vancomycin | Miscellaneous antibiotic prototypes |
| acyclovir, ganciclovir | Antiviral prototypes |
| zidovudine, nevirapine, indinavir | Antiretroviral prototypes |
| isoniazid | Antitubercular prototypes |
| amphotericin B, fluconazole | Antifungal prototypes |
| chloroquine, hydroxychloroquine, primaquine | Antimalarial prototypes |
| metronidazole | Antiprotozoal prototypes |
| mebendazole | Antihelmintic prototypes |
| Trimethoprim/sulfamethoxazole trade name | co-trimoxazole, Bactrim, Septra |
| Erythromycin/sulfisoxazole trade name | Pediazole |
| Amoxicillin trade name | Amoxil, Trimox, Wymox |
| Cefazolin trade name | Kefzol, Ancef |
| Keflex trade name | Cephalexin |
| Cefoxitin trade name | Mefoxin |
| Cefuroxime trade name | Kefurox, Ceftin |
| Ceftriaxone trade name | Rocephin |
| Cefepime trade name | Maxipime |
| Gentamicin trade name | Garamycin |
| Ciprofloxacin trade name | Cipro |
| Imipenm-cilastatin trade name | Primaxin |
| Erythromycin trade name | E-mycin |
| Azithromycin trade name | Zithromax |
| Clarithromycin trade name | Biaxin |
| Aztreonam trade name | Azactam |
| Doxycycline trade name | Vibramycin, Monodox |
| Telithromycin trade name | Ketek |
| Clindamycin trade name | Cleocin |
| Vancomycin trade name | Vancocin, Vancoled |
| Acyclovir trade name | Zovirax |
| Ganciclovir trade name | Cytovene |
| Zidovudine trade name | Retrovir, AZT |
| Nevirapine trade name | Viramune |
| Indinavir trade name | Crixivan |
| Isoniazid trade name | INH |
| Amphotericin B trade name | Amphocin, Fungizone |
| Fluconazole trade name | Diflucan |
| Chloroquine trade name | Aralen |
| Hydroxychloroquine trade name | Plaquenil |
| Metronidazole trade name | Flagyl |
| Mebendazole trade name | Vermox |
| Fentanyl citrate trade name | Duragesic |
| Meperidine HCl trade name | Demerol |
| Methadone HCl trade name | Dolophine |
| Oxycodone trade name | Oxycontin |
| Hydrocodone trade name | Hycodan |
| Naloxone HCl trade name | Narcan |
| Aspirin trade name | acetylsalicylic acid |
| Acetaminophen trade name | Tylenol |
| Indomethacin trade name | Indocin |
| Ibuprofen trade name | Motrin, Advil |
| Ketorolac trade name | Toradol |
| Celecoxib trade name | Celebrex |
| Azathioprine trade name | Imuran |
| Allopurinol trade name | Zyloprim |
| Sumatriptan trade name | Imitrex |
| Sulfonamides: half-life, onset, peak, duration | half-life= 7-12 hr, onset= variable, peak= 2-4 hr (plasma), duration= up to 12 hr |
| Beta-Lactam antibiotics | penicillins, caphalosporins, carbapenems, monobactams |
| Natural penicillins: half-life, onset, peak, duration | half-life= 30 min, onset= variable, peak= 30-60 min, duration= 4-6 hr |
| Aminopenicillins: half-life, onset, peak, duration | half-life= 1-1.3 hr, onset= 0.5-1 hr, peak= 1-2 hr, duration= 6-8 hr |
| Cefazolin: half-life, onset, peak, duration | half-life= 1.2-2.2 hr, onset= variable, peak= 1-2 hr, duration= variable |
| Keflex: half-life, onset, peak, duration | half-life= .05-1.2 hr, onset= variable, peak= 1 hr, duration= 6-12 hr |
| Cefoxitin: half-life, onset, peak, duration | half-life= 30-60 min, onset= variable, peak= 20-30 min, duration= variable |
| Ceftriaxone: half-life, onset, peak, duration | half-life= 4.3-8.7 hr, onset= variable, peak= 2-4 hr, duration= 24 hr |
| Cefepime: half-life, onset, peak, duration | half-life= 2 hr, onset= 0.5 hr, peak= 0.5-1.5 hr, duration= 8-12 hr |
| Imipenem-cilastatin: half-life, onset, peak, duration | half-life= 2-3 hr, onset= variable, peak= 2 hr, duration= 6-8 hr |
| Aztreonam: half-life, onset, peak, duration | half-life= 1.5-2 hr, onset= variable, peak= 1 hr, duration= 6-12 hr |
| Azithromycin: half-life, onset, peak, duration | half-life= 6-8 hr, onset= variable, peak= 2.5 hr, duration= up to 24 hr |
| Clarithromycin: half-life, onset, peak, duration | half-life= 3-7 hr, onset= variable, peak= 2 hr, duration= up to 12 hr |
| Telithromycin: half-life, onset, peak, duration | half-life= 9-10 hr, onset= unknown, peak= 1 hr, duration= unknown |
| Doxycycline: half-life, onset, peak, duration | half-life= 12-24 hr, onset= variable, peak= 1.5-4 hr, duration= up to 12 hr |
| Gentamycin: half-life, onset, peak, duration | half-life= IV 2 hr, onset= vaiable, peak= IV 0.5-2 hr, duration= IV 8-12 hr |
| Ciprofloxin: half-life, onset, peak, duration | half-life= 3-4.8 hr, onset= variable, peak= 1-2.3 hr, duration= up to 12 hr |
| Clindamycin: half-life, onset, peak, duration | half-life= 2.4 hr, onset= variable, peak= 45 min, duration= up to 6 hr |
| Metronidazole: half-life, onset, peak, duration | half-life= 8 hr, onset= unknown, peak= 1-2 hr, duration= unknown |
| Ganciclovir: half-life, onset, peak, duration | half-life= 4-8 hr, onset= unknown, peak= 24 hr, duration= variable |
| Zidovudine: half-life, onset, peak, duration | half-life= 0.78-1.93 hr, onset= unknown, peak= 0.4-1.5 hr, duration= 3-5 hr |
| Nevirapine: half-life, onset, peak, duration | half-life= 25-30 hr, onset= 2 hr, peak= 2-4 hr, duration= 24 hr |
| Indinavir: half-life, onset, peak, duration | half-life= 1.5-2.5 hr, onset= 2 weeks, peak= 0.5-1 hr, duration= 6 months |
| Chloroquine: half-life, onset, peak, duration | half-life= 8-10 days, onset= 8-10 hr, peak= 2 hr, duration= variable |
| Hydroxychloroquine: half-life, onset, peak, duration | half-life= 32-50 days, onset= several hrs, peak= few hr, duration= variable |
| Primaquine: half-life, onset, peak, duration | half-life= >4-6 hr, onset= <2 hr, peak= 1-3 hr, duration= 24 hr |