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M antagonist
| Question | Answer | |
|---|---|---|
| Atropine important notes | Block DUMBBeLS--> except excitation of skeletal m. and CNS(mediated by nicotinic receptors) | Adverse effects: hyperthermia Rapid pulse dry mouth dry and flushed skin cycloplegia constipation disorientation angle closure glaucoma in elderly urinary retention in men with BPH |
| Benztropine, trihexyphenidyl | Muscarinic antagonist--> effects in CNS | Parkinson Dx |
| glycopyrrolate | Muscarinic antagonist--GI, respiratory | Parenteral: peroperative use to reduce airway secretions Oral: drooling, peptic ulcer |
| Hyoscyamine,dicyclomine | Muscarinic antagonist--GI | Antispasmodics for IBS |
| Ipratropium, tiotropium | Muscarinic antagonist--Respiratory | COPD, asthma |
| Oxybutyrnin, solifenacin, tolterodine | Muscarinic antagonist--Genitourinary | Reduce bladder spasms and urge urinary incontinence |
| Scopolamine | Muscarinic antagonist--CNS | Motion sickness |
| Atropine | Muscarinic antagonist | Uses: Treat bradycardia Ophthalmic applications Increase pupil dilation, cycloplegia Decrease airway secretions Decrease gut motility Decrease urgency in cystitis |