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BPH
All about BPH
| Question | Answer |
|---|---|
| What is the Pathophysiology of BPH | Enlargement of prostate that compresses urethra constriction and interfers with urination |
| What do Alpha blocking agents do? | Promote relaxation in the prostate, and relax smooth muscle. BUT DO NOT reduce prostate size. |
| Side effects of Alpha blocking agents | orthostatic hypotension, dizziness |
| What do 5-a-reductase inhibitors do? | Reduce size of prostate Blocks DHT (dihydrotestosterone) |
| Side effects of 5-a-reductase inhibitors | Impotence, and decreased libido |
| types of Alpha blocking agents | doxazosin (Cardura), Terazosin( Hytrin), Tamsulosin(FLomax), Alfuzosin (uroxatral) |
| Clinical ManifestationsBPH: Obstructive | decreased caliber or force of stream, terminal dribbling, retention, difficulty initiating voiding |
| CLinical Manifestations of BPH: Irritative | urgency, dysuria, frequency, incontinence, nocturia |
| Etiology and Risk factors of BPH | Family history, environment, Diet: increased sat. fats (butter, beef), Obesity (increased waist circumference) |
| Complications of BPH | Acute urinary retention, UTI, Septicemia secondary to UTI, bladder calculi, Pyelonephritis, hydronephrosis leading to renal failure. |
| Surgical treatment for BPH | TURP |