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RNSG 1343 Lymphoma
Chapter 29 White blood cell disorders Lymphomas
Question | Answer |
---|---|
Malignant Lymphoma | • Proliferation of lymphocytes, histocytes, and precursors or derivatives • Hodgkin and non-Hodgkin • Malignancies of lymphoid tissue |
• Hodgkin lymphoma | – Develops in a single lymph node or chain of nodes, spreads to adjoining cells – Reed–Steinberg cells – Immune system impairment - Reed-Sternberg Cells |
• Pathophysiology of Hodgkin lymphoma | – Etiology unknown – Contributing factors • Epstein–Barr virus • Genetic factors |
– Manifestations of Hodgkin lymphoma | • Painlessly enlarged lymph nodes in cervical or subclavicular region • Persistent fever • Night sweats |
– Classic “B” Symptoms of Hodgkin lymphoma | • Fatigue, malaise • Weight loss (>10% of normal body weight) • Pruritus • Anemia • Enlarged spleen |
• Non-Hodgkin lymphoma | – Does not contain Reed–Steinberg cells – Etiology unknown – Viral infections can play a role |
Manifestations of Non-Hodgkin lymphoma | • Early, similar to Hodgkin disease – Classic “B” symptoms • Fever, night sweats, fatigue, and weight loss are less common |
• Prognosis of Non-Hodgkin lymphoma determined by | – Stage of disease – Presence of systemic manifestations – Factors such as age - Prognosis good when localized to one or two node regions |
– Diagnostic tests for Lymphoma | – CBC – Erythrocyte sedimentation rate (ESR) – Chemistry studies of major organ function – Chest x-ray– CT scans of chest, abdomen, and pelvis – PET or gallium scans – Biopsy of lymph node and bone marrow |
• Staging of Lymphoma | – Ann Arbor Staging System (Stage I, II, III, IV) |
Stage I of Lymphoma | • Involvement of a single lymph node region or lymphoid structure |
Stage II of Lymphoma | • Involvement of two or more lymph node regions on the same side of the diaphragm |
Stage III of Lymphoma | • Involvement of lymph node regions or structures on both sides of the diaphragm • III1: limited to upper abdomen • III2: involvement of lower abdominal nodes |
Stage IV of Lymphoma | • Involvement of an extranodal site |
Nursing Diagnoses for Lymphoma | • Fatigue • Nausea • Disturbed Body Image • Sexual Dysfunction • Risk for Impaired Skin Integrity |